Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 64-year-old man complained of irritable cough of 3 months' duration and 1 episode of hemoptysis and dyspnea related to effort. The radiograph revealed a mass in the upper right lobe. Adenocarcinoma of the lung was diagnosed by mediastinoscopy. After removal of the right lung, the patient was admitted to the recovery unit for 36 hours and transferred out without complications. The clinical course in 48 hours on the ward included increasing dyspnea, tachypnea and greater respiratory effort with hypoxemia in spite of increased FiO2. A radiograph showed pulmonary edema and the patient was readmitted to the recovery unit. We describe this case of postpneumonectomy edema and discuss the possible origins of the clinical picture, differential diagnosis, preventive measures and possible treatments.
 ...
PMID:[Post-pneumonectomy edema]. 1270 11

Sputum cytology is an important diagnostic tool in pulmonary medicine, but it can yield a false-positive diagnosis of malignancy. We describe such a case, which involved a 70-year-old man who presented with chest pain, hemoptysis, and bilateral pulmonary infiltrates. In the initial evaluation of hemoptysis, multiple sputum samples demonstrated cytological abnormalities consistent with adenocarcinoma, but bronchoscopy found no evidence of malignancy. He was ultimately found to have pulmonary thromboembolic disease with infarction. Follow-up radiographs showed resolution of the pulmonary infarcts, and the absence of malignancy was proven during postmortem examination. Pulmonary infarction is one of many diseases that can produce sputum cytological findings falsely indicative of malignancy.
 ...
PMID:False-positive sputum cytology in a case of pulmonary infarction. 1474 68

A giant bulla of the lung is suggested as a risk factor for lung cancer. Here we report a case with lung cancer in a giant bulla, which showed rapid progression. A 57-year-old man, who had a history of heavy smoking, was admitted to our hospital due to hemoptysis. A chest X-ray revealed a giant bulla with a ground glass shadow and a high fluid level in the right upper lung. Sputum cytology was negative for malignant cells. A chest X-ray a month later showed increases of the size of the radio-opaque shadow and of the air-fluid retention, suggesting pulmonary hemorrhage from the giant bulla. Limited resection or lobectomy was indicated, but pneumonectomy was performed due to the severe air-leak. Macroscopically, a multiple nodular tumor arose from the bulla wall, which might be related to blood flow and necrotic tissue. The postoperative pathological diagnosis was papillary adenocarcinoma. Unfortunately, the patient developed a recurrence of carcinoma in the pleuroperitoneal cavity and died at 2.5 months after the operation. Based on this report and review of other cases in the literature, we should keep in mind the rapid progression of lung cancer in association with an emphysematous bulla.
 ...
PMID:Rapid-growth lung cancer associated with a pulmonary giant bulla: a case report. 1476 78

A retrospective study of clinical manifestations and survival of patients with non-small cell lung cancer (NSCLC) in Sonklanagarind Hospital between 1995-98 was undertaken. There were 209 evaluable NSCLC patients enrolled in the study. NSCLC was common in elderly men who smoked. Major symptoms were cough 74.9%, weight loss 61.6% and dyspnea 54.6%. Chest pain and hemoptysis were presented in only 31.3% and 29.2% respectively. Adenocarcinoma was found in 109 patients (52.1%) , squamous cell carcinoma in 71 patients (34.0%), and large cell carcinoma in 8 patients (3.8%). Only 28 patients (13.4%) were in stage I or II. Surgery was performed in 18 cases (8.6%). Radiation for palliative treatment was used in 74 cases (35.4%). Fifty-four patients (25.8%) received chemotherapy. Forty-two patients received mitomycin, vinblastine and cisplatin regimen (MVP). The response to treatment comprised 3 cases (7.1%) with complete response, and 9 cases (21.4%) with partial response. The survival of the patients in stages I and II was lower than reported from Western countries but in stages III and IV the survival was comparable. Chemotherapy tended to improve survival in advanced stage NSCLC.
 ...
PMID:Clinical manifestation and survival of patients with non-small cell lung cancer. 1522 19

We reviewed our experience on postoperative lobar torsion. From January 1994 to December 2003, 1002 patients underwent lobectomy for lung cancer. Two (0.2%) patients with postoperative lobar torsion required surgical reintervention. The first case was that of a 79-year-old man who underwent left lower lobectomy for pulmonary adenocarcinoma. Based on the postoperative course, lobar torsion was highly suspected with progressive respiratory dysfunction and the chest X-ray showed complete opacification of the residual lobe. Rethoracotomy was performed on postoperative day 4. The left upper lobe was rotated clockwise, and completion pneumonectomy was carried out. The patient died 16 days after the second surgery because of respiratory failure due to severe pneumonia. The second case was that of a 24-year-old man with a diagnosis of metastatic lung cancer in the right upper lobe arising from pharyngeal cancer. The patient underwent right upper lobectomy and developed hemoptysis and persistent high fever. A chest computed tomography (CT) and bronchoscopy findings revealed lobar torsion of the middle lobe, and a reoperation was performed. The middle lobe was resected and the patient was discharged 8 days after the rethoracotomy. Pulmonary lobar torsion poses a difficult diagnostic dilemma in the early postoperative period after the pulmonary resection. Since late reoperation for postoperative lobar torsion sometimes results in poor prognosis, careful observation with bronchial fiberscopy as well as chest radiography is necessary for accurate diagnosis. Rethoracotomy should be carried out without any delay in cases of lobar torsion following pulmonary resection.
 ...
PMID:[Lobar torsion after pulmonary resection for lung cancer]. 1635 16

Endobronchial metastases (EBM) from extrapulmonary malignant tumors are rare. The most common extrathoracic malignancies associated with EBM are breast, renal and colorectal carcinomas. In this study, we aimed to evaluate the clinical, radiographic and bronchoscopic aspects of patients with EBM who were diagnosed between 1992 and 2002. Data about patients' clinical conditions, symptoms, radiographic and endoscopic findings, and histopathological examination results were investigated. EBM was defined as bronchoscopically visible lesions histopathologically identical to the primary tumor in patients with extrapulmonary malignancies. We found 15 cases with EBM. Primary tumors included breast (3), colorectal (3), and renal (2) carcinomas; Malignant Melanoma (2); synovial sarcoma (1), ampulla of Vater adenocarcinoma (1), pheochromocytoma (1), hypernephroma (1), and Hodgkin's Disease (1). The most common symptoms were dyspnea (80%), cough (66.6%) and hemoptysis (33.3%). Multiple (40%) or single (13.3%) pulmonary nodules, mediastinal or hilar lymphadenopathy (40%), and effusion (40%) were the most common radiographic findings. The mean interval from initial diagnosis to diagnosis of EBM was 32.8 months (range, 0-96 months) and median survival time was 18 months (range, 4-84). As a conclusion, various extrapulmonary tumors can metastasize to the bronchus. Symptoms and radiographic findings are similar with those in primary lung cancer. Therefore, EBM should be discriminated from primary lung cancer histopathologically. Although mean survival time is usually short, long-term survivors were reported. Consequently, treatment must be planned according to the histology of the primary tumor, evidence of metastasis to other sites and medical status of the patient.
 ...
PMID:Endobronchial metastases from extrathoracic malignancies. 1647 29

A 47-year-old man was admitted to our hospital for treatment of massive hemoptysis. He was intubated and underwent bronchial arterial embolization because of this deteriorating respiratory state and uncontrollable hemoptysis. Computed tomography (CT) of the chest showed a 1-cm nodular shadow in the peripheral apical lobe (S1) of the right lung. He underwent right upper lobectomy for the purpose of preventing re-hemorrhage as well as making the definitive diagnosis of nodular shadow in S1 of the right lung. Intraoperative pathological examination revealed the nodule as adenocarcinoma, and mediastinal lymphadenectomy was added to the right upper lobectomy. The patient recovered uneventfully, and there has been no sign of recurrence for 15 months after the operation.
 ...
PMID:[Small peripheral lung cancer incidentally detected by massive hemoptysis]. 1671 91

A 55-year-old male presented with asymptomatic nodules and plaques on his scalp and pubic region of 2 months' duration. He was having productive cough, haemoptysis, chest pain, anorexia and weight loss and receiving antitubercular treatment for these symptoms for last 3 months. Clinical diagnosis of cutaneous metastatic disease was made. Chest x-ray revealed multiple coin shaped shadows on both sides with pleural effusion. Routine investigations were normal except for anemia and hyperuricemia. Biopsy of skin nodules showed features of metastatic adenocarcinoma. Features and significance of cutaneous metastases are discussed.
 ...
PMID:Cutaneous metastatic adenocarcinoma. 1766 46

Endotracheal metastases (ETM) from non-lung cancer are seldom seen. Their main clinical symptoms are cough, haemoptysis and dyspnoea, although occasionally an incidental finding is made during a bronchoscopy. Breast, colon and kidney adenocarcinoma might be associated with ETM, lung cancer being the most frequent cause. Its finding is associated with advanced disease but survival will depend on the primary origin, patient status and comorbidity. Therefore, treatment should be individual for each patient. In our centre we recommend pre-surgery bronchoscopy to exclude metastatic endotracheal lesions in patients with metastatic colon adenocarcinoma disease, as this might affect the final outcome and therefore management of the disease.
 ...
PMID:Endotracheal metastases from colon adenocarcinoma. 1894 Jul 51

The aim of this study was to retrospectively review the indications, results and complications of flexible fiberoptic bronchoscopy (FFB) in an University teaching Hospital. Also, we present the radiological findings for the major causes according to computed tomography of the chest performed within 48 h of fiberoptic bronchoscopy. A total of 4,098 FFBs were performed from January 1, 2003 to December 30, 2007. For diagnostic purposes, 3769 FFBs performed (92%) and for therapeutic purposes 329 FFBs (8%) performed. Haemoptysis was the most common indication for FFB (21%), followed by fever/suspected infection (19%) and chronic cough (18%). The most common results of the diagnostic workup was nonspecific inflammation of the tracheobronchial tree (31% for haemoptysis, 38.7% for fever and 48.5% for chronic cough), with malignancy ranking second (17%, 26.1% and 26% respectively). The cytological results showed adenocarcinoma to be the most common lung cancer in both sexes (37.3% for men and 39.7% for women). The mortality rate was 0.04% and the frequency for major and minor complications was 0.56% and 0.33%, respectively. In conclusion, flexible fiberoptic bronchoscopy is a safe procedure and can play a major role in both diagnosis and treatment, as long as the requisites of preparation and supervision are followed.
 ...
PMID:Indications, results and complications of flexible fiberoptic bronchoscopy: a 5-year experience in a referral population in Greece. 1914 97


<< Previous 1 2 3 4 5 6 7 8 9 Next >>