Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report the case of a 64-year-old woman who presented with massive hemoptysis. She was found to be bleeding from a pulmonary arteriovenous malformation in the right middle lobe, which had a peculiar blood supply from the right internal mammary artery. Video-assisted thoracic surgery lobectomy was successfully performed for this condition. Limitations of embolization as a treatment modality for this condition are discussed.
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PMID:Hemoptysis from an unusual pulmonary arteriovenous malformation. 1460 28

A 33 years old woman was admitted to the hospital after four days with cough, dyspnea, orthopnea and hemoptysis. Blood pressure was 170/90 mmHg, pulse was 112 and temperature was normal. She had cyanosis and a left ventricular gallop, without heart murmurs. A chest radiograph revealed pulmonary edema and echocardiogram showed a global left ventricular systolic disfunction. Oxygen and furosemide were started, but cardiopulmonary collapse ensued. The patient was supported with mechanical ventilation and treated with inotropic drugs. A right sided cardiac catheterization showed pulmonary wedge pressure of 18 mmHg and a cardiac index of 3 l/min/m2. The levels of creatinine and urea nitrogen were elevated and a urine protein was 97 mg/dl. Coagulation tests were normal except by a positive lupic anticoagulant. Markers of connective tissue diseases or vasculitis were negatives. The clinical evolution suggested that a catastrophic antiphospholipid syndrome was ongoing. Intravenous corticoids, gammaglobulin and cyclophosphamide were administered with transient improvement. On her fourth day of treatment, the patient presented sudden pulmonary bleeding and embolism. A plasmapheresis was performed with improvement of renal, cardiac and pulmonary function. After this episode, the patient has been treated with prednisone and oral anticoagulants treatment for the last two years, without further clinical events.
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PMID:[Catastrophic antiphospholipid syndrome and acute heart failure. Report of a case]. 1463 91

Glomus tumor of the trachea is extremely rare. There were approximately 15 reported cases before. Herein, we report another case of glomus tumor of the trachea in a 50-year-old woman presenting with cough and dyspnea for 8 years. She suffered from hemoptysis for 1 day before this admission. Bronchoscopy and CT scan showed a polypoid tumor protruding into the tracheal lumen and with extraluminal extension. The tumor was located at 9 cm below the vocal cord and 1.5 cm above the carina. It measured 2.5 x 2.5 x 2.0 cm and arose from the posterior wall of the trachea. Microscopically, the tumor consisted of a sheet of uniform cells surrounding the vascular spaces. Only few scattered tumor cells showed weak positive staining for muscle actin (HHF-35) by immunohistochemical stain. Ultrastructural study confirmed the presence of small amount of myofibrillar bundles with focal densities in some of the tumor cells. Other cells exhibited only rare or very sparse myofilaments. Characteristic feature of fine pinocytotic vesicles along the plasma membrance of the tumor cells was also noted.
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PMID:Glomus tumor of the trachea. 1464 80

A 65 year old female patient presented with one episode of massive haemoptysis requiring transfusion and subsequently cough with streaky haemoptysis. Computerized tomographic scan and angiogram revealed aneurysm of the distal aortic arch. She underwent elective repair of the pseudoaneurysm through median sternotomy and the bronchial communication was closed through left thoracotomy. Tubercle bacilli were identified in the contents and excised wall of aortic tissue.
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PMID:Repair of tuberculous aneurysm of distal aortic arch. 1468 Oct 99

A 51-year-old woman was admitted to our hospital with a diagnosis of acute myeloid leukemia (M1) in January 2002. During the course of induction therapy, she developed a fever and chest radiography revealed bilateral infiltrates. She was treated with broad-spectrum intravenous antibiotics and fluconazole, but her condition continued to worsen. She then began receiving amphotericin B, although there was no evidence of a fungal infection from the sputum culture and serologic testing. The patient soon became afebrile and improved clinically. On the 87th hospital day, however, she had a bout of abrupt massive hemoptysis and died of exsanguination. The diagnosis of aortobronchial fistula due to pulmonary mucormycosis was obtained at autopsy. Because of the angioinvasive tendency of mucormycosis, fatal hemoptysis in some patients with pulmonary mucormycosis has been reported, but most cases involve hemoptysis resulting from mucor invasion of the pulmonary artery. To our knowledge, this case represents the fourth description of pulmonary mucormycosis with fatal bleeding from the aorta.
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PMID:[Aortobronchial fistula induced by pulmonary mucormycosis in acute myeloid leukemia]. 1519 48

An aneurysm of the descending thoracic aorta was found in a 55-year-old woman. She had hemoptysis, fever, and weight loss beginning 1 month before hospitalization. A miliary tuberculosis developed after angiography. The patient underwent surgical resection of the aneurysm, which proved to be tuberculous. The aortic wall was reconstructed with a Dacron patch. Antituberculosis pharmacotherapy, started before operation, was discontinued after 16 months of administration. The patient is doing well 19 months after operation. The English literature reports only 7 other cases of surgical treatment of tuberculous aneurysm of the thoracic aorta. According to previous reports, early surgical intervention, combined with preoperative and prolonged postoperative antituberculosis therapy and close postoperative follow-up, is mandatory in this group of patients.
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PMID:Successful resection of a tuberculous pseudoaneurysm of the descending thoracic aorta: case report and review of the literature. 1522 27

Eisenmenger syndrome is the most common consequence of congenital cyanotic heart disease seen in adults; survival to the fifth decade of life is rare. Death is very difficult to predict: it is related to sudden cardiac ventricular arrhythmia, massive hemoptysis and right heart failure. In this paper, a patient with ventricular septal defect and Eisenmenger reaction is described. The patient was relatively well until 48 years of age, when she underwent surgery because of a cerebral abscess without cerebral complications but with some deterioration of her cardiac function. After discharge, the patient was readmitted to the hospital because the electrocardiogram showed persistent ST inferior elevation. Echocardiography demonstrated poor contractility and inferior akinesia. Sudden ventricular tachycardia occurred and the patient became unconscious. She was successfully resuscitated and, following a period of ventilation, the hemodynamics stabilized and she was discharged 17 days later. She remained well two years later.
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PMID:Eisenmenger syndrome: a case of survival after ventricular tachycardia due to inferior myocardial infarction in a 48-year-old patient with congenital large ventricular septal defect. 1522 66

A 56-year-old Jewish woman of Ashkenazi origin had a history of tuberculosis since the age of 1 year, contracted while she was in hiding in Poland during the Holocaust. She developed bronchiectasis in 1972 for which she was being treated 4 times a year for 1-month periods with 600 mg/d rifampin. During the Persian Gulf War in February 1991, a month after a rifampin treatment, she was admitted to the dermatology department with cutaneous and oral mucous eruptions. Physical examination revealed crusting bullae and erosions on the trunk and lower limbs. The mucous membranes were affected in the vagina, oral cavity, and pharynx. Histologic and immunofluorescence studies on a biopsy specimen confirmed the diagnosis of pemphigus vulgaris. There was no family history of the disease. Systemic treatment with prednisone,100 mg/d, resulted in regression of the eruption within a month, and the dose was tapered to 10 mg every second day. Although she received anti-tuberculosis treatment, the steroids caused an exacerbation of the tuberculosis, and after a massive hemoptysis in 1993, a right upper and middle lobectomy was performed. The operation put an end to the vicious cycle of drug-induced pemphigus outbreaks by eliminating the need for rifampin, but the patient reported the appearance of new lesions during periods of emotional stress.
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PMID:Pemphigus vulgaris triggered by rifampin and emotional stress. 1536 72

A 29-year-old woman was admitted to our hospital with a 7-day history of elevated temperature to 39.5 degrees C associated with headache and nausea. She had been diagnosed with tuberous sclerosis complex 10 years earlier. Her unconsciousness progressed, and she was diagnosed as having aseptic meningoencephalitis. The next day, she had a generalized seizure with severe hemoptysis, and she suddenly fell into severe respiratory failure (PaO2/FiO2 = 76.9). Transbronchial lung biopsy revealed the findings of lymphangioleiomyomatosis. It was suggested that neurogenic pulmonary edema accompanied with venous flow obstruction by lymphangioleiomyomatosis lesions resulted in diffuse pulmonary hemorrhage with resultant gross hemoptysis accelerating to severe hypoxemia.
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PMID:Acute respiratory failure with gross hemoptysis in a patient with lymphangioleiomyomatosis as part of tuberous sclerosis complex. 1546 81

A 66-year-old woman was transferred to our hospital for emergency treatment of a ruptured abdominal aortic aneurysm (AAA) and impending rupture of a descending thoracic aortic aneurysm (TAA) caused by a Stanford type-B dissection. She had severe coronary artery disease and a highly calcified aorta, and had been taking long-term steroids for rheumatoid arthritis. Endovascular repair of the TAA failed because the femoral artery was too small, so we performed simultaneous repair of the TAA and the AAA. A temporary axillofemoral bypass was constructed and the AAA was replaced with a bifurcated prosthetic graft. A thoracic stent graft was delivered successfully through a chimney graft of the abdominal graft. About 4 months later, the TAA extended proximally, causing hemoptysis, which was stopped by placing a new stent graft proximal to the previous one. This case report shows that a combination of open and endovascular repair is useful for treating a TAA with an AAA, especially in a small or frail patient.
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PMID:Simultaneous open and endoluminal repair of ruptured abdominal and thoracic aortic aneurysms: report of a case. 1552 34


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