Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019045 (hemoglobinopathies)
 2,704 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hemoglobin 1061
erythroid 198
beta-globin 166
Sep 153
Mol 128
methemoglobin 94
HBB 80
ferritin 63
gamma-globin 56
BCL11A 48
HLA 48
erythropoietin 36
CD34 29
She 24
HBA2 23
transferrin 22
beta globin 21
AAG 19
alpha globin 19
gamma globin 17
more...
Disease
hemoglobinopathies 2704
thalassemia 948
sickle cell disease 809
anemia 350
thalassemia major 121
hemolytic anemia 114
malaria 103
beta thalassemia 95
cancer 95
iron deficiency 91
HBB 80
HBB 80
HBB 80
diabetes 77
iron overload 72
thalassemia trait 66
graft-versus-host disease 47
stroke 42
tumor 41
leukemia 40
more...
Symptom
pain 67
splenomegaly 46
cyanosis 18
anesthesia 16
abdominal pain 12
hepatosplenomegaly 11
headache 9
weakness 9
chest pain 7
collapse 7
seizures 7
fatigue 6
dyspnea 6
pallor 5
flank pain 5
shortness of breath 4
cough 4
back pain 4
hypothermia 4
diarrhea 4
more...
Drug
Asn 11
VCR 8
lysine 7
ascorbate 6
Leaf 6
TAT 6
Deferasirox 5
Dermatol 5
Fluorescein 5
Fluorescein 5
Dakar 5
Cellulose acetate 4
ROS 4
Heme 4
FAD 3
Bayer 3
G-CSF 3
Nephron 3
MDS 3
Prednisone 2
more...
Enzyme
ERK 23
glucose-6-phosphate dehydrogenase 19
endonuclease 8
lactate dehydrogenase 7
TAT 6
APC 5
superoxide dismutase 5
pyruvate kinase 5
aspartate aminotransferase 5
mitogen-activated protein kinase 5
catalase 5
peroxidase 5
RNA polymerase 4
biotinidase 4
thrombin 4
trypsin 4
aldehyde dehydrogenase 4
arginase 4
alkaline phosphatase 4
GCA 3
more...
Compound
Hemoglobin 355
Clin 272
DNA 263
iron 193
Dec 152
oxygen 139
HBB 80
glucose 35
lysine 34
acetate 33
Asp 26
His 25
Hydroxyurea 21
urea 20
arginine 20
zinc 19
MCH 17
alanine 16
sodium 16
leucine 15
more...