Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019045 (hemoglobinopathies)
 2,704 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It is estimated that approximately 2 percent of African-Americans possess one gene for C hemoglobin. This is usually demonstrated on hemoglobin electrophoresis. Hemoglobin C trait (AC hemoglobinopathy) is considered a clinically benign condition; there are no characteristic physical abnormalities. Angioid streaks in the ocular fundus represent a progressive, bilateral, degenerative disorder characterized by breaks in Bruch's membrane. The pathogenesis of angioid streaks in the hemoglobinopathies is thought to be linked to iron deposition in Bruch's membrane. This report describes what is believed to be the first reported case of angioid streaks associated with hemoglobin C trait.
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PMID:Angioid streaks and AC hemoglobinopathy--a newly discovered association. 831