Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018991 (
hemiplegia
)
3,997
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The hyper-immunoglobulin E (IgE) syndrome (
HIES
), also known as Job's syndrome is a rare primary immunodeficiency characterized by the clinical triad of recurrent staphylococcal abscesses of skin, recurrent cyst-forming pneumonia, and an elevated serum IgE level of > 2000 IU/ml. Although, most cases are sporadic, families with autosomal dominant (AD-
HIES
) and recessive (AR-
HIES
) traits have been reported. Very few articles were published previously on central nervous system abnormalities with definite neurologic manifestations which may vary from partial facial nerve paralysis to
hemiplegia
in children but Acute Disseminated Encephalomyelitis (ADEM) in a child with
HIES
hitherto has not been reported. Here we describe a 5-year-old male child with
HIES
who presented with neurologic manifestations of ADEM.
...
PMID:Acute disseminated encephalomyelitis: an uncommon presentation of hyper IgE syndrome. 2551 94
