Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018991 (hemiplegia)
 3,997 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Case 1. A seven-year-old boy was admitted to our hospital shortly after developing right hemiplegia and motor aphasia during rope-jumping play. Neither cervical trauma nor signs of cervical and pharyngeal inflammation were present. The physical examination was negative. The carotid angiogram on the day of admission gave poor visualization of the middle cerebral artery group, although the computerized tomographic finding was not remarkable. His neurological status gradually got better, while the routine laboratory studies gave only a slight increase of ESR (26 mm/hour) and positive CRP(I+). There were no particular findings of CSF from lumbar tap or of serological studies. The second computerized tomographic scan 42 hours after clinical onset showed a wide low dense area with obscure margin in the left parieto-temporal region, which was enhanced variously with intravenous contrast media. In about ten days his clinical state was remarkably improved. The second carotid angiogram one month after admission showed a poor filling of the middle cerebral artery territory and beaded appearance of the artery. The patient was discharged on the 46th day with a minimum right hemiparesis. Case 2. A ten-year-old boy was admitted with complaint of right hemiparesis and motor aphasia developing at night. The physical examination was negative. The laboratory studies were also negative. The computerized tomographic scan five days after onset showed a low dense area in size of 2 x 1.5 x 2 cm in the region of the left Nucleus lentiformis. No enhancement effect was seen. The left carotid angiogram on the same day revealed stenotic lesions at the M1 and the posterior temporal artery.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Cerebral ischemic lesions in children and primary cerebral angiitis: report of two cases]. 380 15

Spinal subdural hematoma following lumbar puncture occurred in a patient with embolic hemiplegia. The authors discuss the possible responsibility of heparin administered immediately after the tap. Physiological mechanisms of spinal subdural hematoma are reviewed. The authors emphasize the poor prognosis associated with this rare complication. They suggest that anticoagulant therapy be discontinued during and after a spinal tap. The first signs of medullary and radicular compression should be promptly recognized and an emergency neurosurgical procedure undertaken in order to forestall definitive paraplegia.
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PMID:[Spinal subdural hematoma. An unusual complication of lumbar puncture (author's transl)]. 628 1

The glabellar reflex (GR) was investigated in 15 patients with hemiplegia and in 10 control subjects. The reflex was elicited mechanically by a light tap on the glabella. The EMG-responses were recorded bilaterally from the orbicularis oculi muscles by pairs of surface electrodes. The EMG activities were averaged and integrated off-line. In addition, the latencies of the early and late components were determined. Two major types of the GR alterations could be distinguished. These two patterns probably indicate a lowered excitability of the brainstem trigeminal systems or brainstem facial systems respectively. A loss of facilitatory influences associated with the hemispheral lesion seems probable. The alterations of the early component showed essential linkage to those of the late component. The latencies of GR responses on both sides were frequently prolonged. This fact and the decrease of the GR responses on the unaffected side as well as on the affected side indicates that the glabellar reflex can be altered bilaterally in hemiplegic patients.
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PMID:Quantitative analysis of the glabellar reflex in patients with hemiplegic disorders. 662 89

A 57-year-old woman complained of severe headache and vomiting of a week's duration. Spinal tap showed bloody CSF and cerebral angiography revealed the "true" posterior communicating artery aneurysm. Left frontotemporal osteoplastic craniotomy and trapping of the aneurysm were performed on August 28, 1979. After operation right hemiplegia, left oculomotor palsy and the disturbance of consciousness developed. Postoperative CT scan showed a hemorrhagic infarction at the left basal ganglia. Since then she has been getting better and was discharged, able to walk, from our hospital 6 months after operation. We considered the anatomical importance of perforating arteries from posterior communicating artery and propose that true posterior communicating artery aneurysm should be classified separately from our experiences and literature.
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PMID:[A case of "true" posterior communicating artery aneurysm (author's transl)]. 729 Mar 21

The purpose of this research was to verify in a group of hemiplegic subjects the usefulness of potentials obtained with tendon tap by evaluating the integrity of the proprioceptive area in relation to lesions in the middle cerebral artery territory. The healthy and paretic sides in 10 subjects affected by hemiplegia have been studied using the cerebral potential evoked by tendon tap. Two sets of 150 stimuli for each lower limb were applied at a standard repetition rate of 1 stimulus per 16 seconds. Data obtained shows a reduction of the amplitude of the P1-N1 cortical complex derived from the paretic side. This effect appears to be related to the entity of the kinaesthetic sensitivity impairment.
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PMID:Evoked potentials obtained with tendon percussion in hemiplegic patients. 849 56

Effects of NBP on liability of stroke, life span and neurological deficits following stroke were studied in stroke prone spontaneously hypertensive rats (SHRsp). The SHRsp rat was kept on 1% NaCl solution as drinking water and was fed 15 g soft food containing 0.6-0.8 g NaCl per day. Total NaCl intake for one rat was 1.1-1.3 g per day. After the onset of stroke, tap water and normal food was given instead of that containing NaCl. The neurological deficits were evaluated by a specially designed scoring system. These symptoms were divided into 4 degrees (1-4). Grade 1. stress (mild). Grade 2. forelimb or head twitch or with stress (severe). Grade 3. hemiparalysis, body inclined or disabled. Grade 4. paralysis, tremor or convulsion. Blood pressure, heart rate and body weight were measured once every 2 weeks. The weights of heart, brain and kidneys were also measured. The results show that NBP pre-treatment at the dose of 100 mg.kg-1.d-1 po delayed the onset of stroke. So, like nimodipine, NBP showed a stroke preventive action in SHRsp rats. In addition, treatment with NBP 100 mg.kg-1.d-1 po after the onset of stroke, the life span was prolonged and the score of neurological deficit decreased significantly. Because high blood pressure can not be lowered by NBP treatment, therefore, the protective effect against stroke can not be explained by the effect of hypotension. No change was found in BP, HR and the organ weight. The results indicate that NBP is expected to be useful in the treatment of stroke.
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PMID:[Effect of dl-3-n-butylphthalide (NBP) on life span and neurological deficit in SHRsp rats]. 876 59

A 10-year-old neutered male Persian cat and a 4-year-old spayed female domestic shorthair (DSH) cat were evaluated for acute-onset severe lateralising tetraparesis and hemiplegia, respectively. Both cats also had left-sided Horner's syndrome. Neurological examination of the cats localised the lesion to cranial to C5 in the Persian and the left cervical intumescence (C6-T2) in the DSH. Physical examinations were otherwise generally unremarkable. Routine laboratory tests and spinal radiography were normal for the Persian cat and were not performed for the DSH cat. A cerebrospinal fluid (CSF) tap was attempted for the Persian cat but aborted because of gross blood contamination, and was not performed for the DSH cat. Magnetic resonance imaging (MRI) of the Persian cat revealed a lesion within the spinal parenchyma at segments C1 to C3 (slightly more left-sided) which was iso- to hypointense on T1-weighted scans and hyperintense on T2-weighted scans, and which enhanced slightly with gadolinium. MRI of the DSH cat revealed a lesion within the spinal parenchyma at segment C7 (predominantly left-sided) which was hypointense on T1-weighted scans and hyperintense on T2-weighted gradient echo scans. Contrast was not administered. The MRI findings in both cases were highly suggestive of acute spinal cord infarction, based upon comparison to human cases. Both cats made full neurological recoveries with supportive treatment only. This paper describes two cases of suspected acute spinal cord infarction in the cat, demonstrates the potential diagnostic value of MRI, and discusses the clinical syndrome of this condition with a brief review of published cases.
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PMID:MRI characteristics of suspected acute spinal cord infarction in two cats, and a review of the literature. 1577 46