Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018991 (
hemiplegia
)
3,997
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Two cases of promyelocytic leukemia (
APL
) with central nervous system leukemia (CNS-L) are reported. The first case displayed some symptoms similar to meningitis at onset, and the second case, during induction therapy suddenly developed left
hemiplegia
and was found to have CNS-L. There have been only a few case reports of
APL
associated with CNS-L and each has said that
APL
was rarely accompanied by CNS-L. Yet, of the reports registered with the Joint Committee for Hematologic neoplasm in Japan, the incidence of
APL
with CNS-L is not much lower than any of the other types of acute non-lymphocytic leukemia that can accompany a CNS-L. There fore, we feel that CNS-L should not be overlooked as an important prognostic consideration in
APL
cases.
...
PMID:[Acute promyelocytic leukemia with central nervous system leukemia--a report of two cases]. 317 21
