Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018991 (
hemiplegia
)
3,997
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Abnormal movements of the body segments due to lowest level gait disorders such as musculoskeletal disorders, peripheral neuropathies and radiculopathies or middle-level disorders such as
hemiplegia
, paraplegia and dystonia influence the motion of the centre of gravity (CG) during walking. The translation of the CG can be studied by the work done by muscles (WExt) with respect to the ground. The efficacy of gait's mechanism can be quantified by the energy transferred between gravitational potential and kinetic energies (recovery). WExt and recovery were investigated in lowest and middle-level gait disorders during level walking. No statistical significant difference was observed between patients with lowest-level gait disorders and normal subjects. However, WExt was increased for the patients with middle-level gait disorders and recovery decreased up to 20%. The measurement of changes in mechanical energy of the CG might be a summary indicator for the mechanics of pathological gait.
Gait
Posture
2000 Dec
PMID:Motion of the body centre of gravity as a summary indicator of the mechanics of human pathological gait. 1115 35
The purpose of this study was to investigate the impact of three different ankle foot orthoses (AFO) configurations on the function and kinematics of stair locomotion in children with spastic
hemiplegia
. Nineteen children were evaluated barefoot and with a hinged, posterior leaf spring (PLS) and solid AFO during stair ascent and descent. Stair specific items from the Pediatric Evaluation of Disability Inventory (PEDI) were used to evaluate function, while a motion measurement system was used to evaluate kinematics. The PEDI revealed no significant differences between AFOs and barefoot, although a greater percentage of children were able to keep up with their peers while wearing a hinged AFO. At the ankle, the hinged AFO provided the greatest amount of dorsiflexion during stance. All AFOs reduced plantarflexion in comparison to barefoot. The results of this study indicate that for children with spastic
hemiplegia
the use of an AFO did not impair stair ambulation.
Gait
Posture
2002 Oct
PMID:Stair locomotion in children with spastic hemiplegia: the impact of three different ankle foot orthosis (AFOs) configurations. 1229 58
Ankle equinus is the most commonly identified impairment of individuals with spastic
hemiplegia
(SH). However, it is not clear how equinus at the ankle may contribute to gait deviations at other joints. The purpose of this study was to determine what compensatory gait deviations may occur as a result of an imposed, unilateral equinus constraint. Gait data were collected on 12 adult subjects with and without one ankle constrained in equinus using a unique taping method. Knee extension at initial contact, knee extension in mid stance, and hip extension at terminal stance were all found to be significantly reduced on the ipsilateral side as a result of the ankle constraint. On the unconstrained or contralateral side, subjects tended to adopt a foot-flat or toe-first initial contact pattern. This study suggests that stance phase limitations in both hip and knee extension in the gait of persons with
hemiplegia
are not necessarily caused by limited length of the involved side hamstrings and/or hip flexors, but rather that they can occur as the result of an ankle plantarflexor contracture alone. Deviations in the contralateral foot contact pattern can also occur secondary to unilateral equinus and should not be assumed to represent bilateral involvement.
Gait
Posture
2004 Dec
PMID:Secondary gait compensations in individuals without neuromuscular involvement following a unilateral imposed equinus constraint. 1553 Nov 70
Several studies indicated that walking with an ankle foot orthosis (AFO) impaired third rocker. The purpose of this study was to evaluate the effects of two types of orthoses, with similar goal settings, on gait, in a homogeneous group of children, using both barefoot and shoe walking as control conditions. Fifteen children with
hemiplegia
, aged between 4 and 10 years, received two types of individually tuned AFOs: common posterior leaf-spring (PLS) and Dual Carbon Fiber Spring AFO (CFO) (with carbon fibre at the dorsal part of the orthosis). Both orthoses were expected to prevent plantar flexion, thus improving first rocker, allowing dorsiflexion to improve second rocker, absorbing energy during second rocker, and returning it during the third rocker. The effect of the AFOs was studied using objective gait analysis, including 3D kinematics, and kinetics in four conditions: barefoot, shoes without AFO, and PLS and CFO combined with shoes. Several gait parameters significantly changed in shoe walking compared to barefoot walking (cadence, ankle ROM and velocity, knee shock absorption, and knee angle in swing). The CFO produced a significantly larger ankle ROM and ankle velocity during push-off, and an increased plantar flexion moment and power generation at pre-swing compared to the PLS (<0.01). The results of this study further support the findings of previous studies indicating that orthoses improve specific gait parameters compared to barefoot walking (velocity, step length, first and second ankle rocker, sagittal knee and hip ROM). However, compared to shoes, not all improvements were statistically significant.
Gait
Posture
2006 Oct
PMID:How can push-off be preserved during use of an ankle foot orthosis in children with hemiplegia? A prospective controlled study. 1693 70
The purpose of this study was to investigate the changes in electromyographic (EMG) patterns after multilevel surgical treatment in children with spastic cerebral palsy. Children with diplegia (n=18) and
hemiplegia
(n=16) aging from 6 to 16 years participated in the study. Twenty healthy children within the same age span are presented as reference. Gait analysis and surface electromyograms of seven major lower limb muscles were assessed before and 1-5 years after the multilevel surgery. The most frequent procedures were equinus correction, distal rectus femoris transfer, femoral derotation osteotomy and hamstrings lengthening. The results showed that the EMG pattern of the soleus, lateral gastrocnemius and tibialis anterior muscles became closer to normal after the surgery, while no differences were detected between diplegic and hemiplegic patients. Furthermore, a subgroup of 10 patients showed an increase in medial hamstrings activation during preswing that decreased postoperatively. These findings indicate that changes in EMG patterns should not be ruled out after surgical treatment, although the extent of these changes is limited compared to changes in the kinematics. Abnormal muscle activation before the operation can be related to a compensatory response in some patients and this can be manipulated after surgery.
Gait
Posture
2007 Sep
PMID:Electromyographic patterns in children with cerebral palsy: do they change after surgery? 1714 Jul 96
Surface electromyography (sEMG) is part of an instrumented gait assessment, however, the interpretation of the data in a clinically meaningful manner is often limited to the extraction of individual sEMG characteristics. The purpose of this study was to develop an assessment methodology using sEMG time and frequency characteristics extracted using wavelet analyses to provide clinically relevant information in children with cerebral palsy (CP). A retrospective study was conducted with 37 children (16 children with typical development (TD) and 21 children with spastic CP). sEMG signals were examined from selected musculature of the lower extremities during level ground walking. Wavelet analysis techniques, along with functional principal component analyses, were employed to calculate a sEMG index. The data indicated a grouping in the EMG index based on the level of motor impairment and the clinical diagnosis of spastic
hemiplegia
or diplegia. Further analyses of the index exhibited moderate to high (r=-0.43 to -0.74 and r=0.62-0.65) correlations with the existing gait kinetics, kinematics, and clinical measures of motor impairment, and was sensitive to walking ability according to the Gross Motor Functional Classification Scale (GMFCS). Overall, this methodology may have the potential to provide additional insight into the outcome of a clinical intervention that was not available previously, and may find use as a predictive tool that can be utilized for clinical decision making.
Gait
Posture
2007 Sep
PMID:A time-frequency based electromyographic analysis technique for use in cerebral palsy. 1716 3
The purpose of this study was to investigate gait asymmetry in chronic stroke patients in comparison with subjects with no known asymmetries. Further, we wanted to decide which gait symmetry parameter has the best ability to discriminate between the two groups. Twenty subjects with
hemiplegia
(mean age 58 years, S.D.=8 years) and 57 subjects with no known gait asymmetry (mean age 77 years, S.D.=5 years) walked six times along a 7-m walkway at slow, preferred and fast speed. Measures of vertical, anteroposterior, and mediolateral trunk asymmetry were assessed from triaxial accelerometry data. The footfall parameters of single support (% of stride time) and step length (m) asymmetry were assessed from data obtained using an electronic walkway. Vertical (p<0.001), anteroposterior (p=0.01), mediolateral (p=0.01) trunk movement and single support (p=0.03) showed significant differences in asymmetry between the two groups. No difference in step length asymmetry was found between the two groups. Neither single support asymmetry nor step length asymmetry showed the ability to discriminate subjects with hemiplegic gait from subjects in the comparison group. Measures of trunk movement asymmetry, however, were able to discriminate between the two groups (p<or=0.001). The results indicate that trunk movement should be included in the assessment of gait asymmetry in chronic stroke patients.
Gait
Posture
2008 May
PMID:Should trunk movement or footfall parameters quantify gait asymmetry in chronic stroke patients? 1789 30
Modelling the effect of soleus and gastrocnemius contractions against the floor resistance in a forward dynamics simulation revealed that hip flexion, internal rotation and adduction together with external pelvic rotation could be attributed to a direct, but distant effect of triceps surae contraction. Knee flexion smoothed out the effect. To validate this clinically relevant biomechanical observation, ankle plantar flexion was correlated with hip and pelvic rotation retrospectively in children with spastic cerebral palsy. In 49 children with spastic
hemiplegia
, plantar flexion showed a significant correlation with increased pelvic retraction and hip internal rotation. In contrast, in 47 children with spastic diplegia no significant effect of the triceps surae on hip and pelvis kinematics was found. Bilateral hip and knee flexion in diplegia appeared to prevent the proximal effect of the triceps surae seen in the hemiplegics. In diplegia triceps surae overactivity did not appear to be a significant cause of internal rotation gait.
Gait
Posture
2008 Jul
PMID:Effects of plantarflexion on pelvis and lower limb kinematics. 1825 30
This article describes a new multivariate measure of overall gait pathology called the Gait Deviation Index (GDI). The first step in developing the GDI was to use kinematic data from a large number of walking strides to derive a set of mutually independent joint rotation patterns that efficiently describe gait. These patterns are called gait features. Linear combinations of the first 15 gait features produced a 98% faithful reconstruction of both the data from which they were derived and 1000 validation strides not used in the derivation. The GDI was then defined as a scaled distance between the 15 gait feature scores for a subject and the average of the same 15 gait feature scores for a control group of typically developing (TD) children. Concurrent and face validity data for the GDI are presented through comparisons with the Gillette Gait Index (GGI), Gillette Functional Assessment Questionnaire Walking Scale (FAQ), and topographic classifications within the diagnosis of Cerebral Palsy (CP). The GDI and GGI are strongly correlated (r(2)=0.56). The GDI scales with FAQ level, distinguishes levels from one another, and is normally distributed across FAQ levels six to ten and among TD children. The GDI also scales with respect to clinical involvement based on topographic CP classification in
Hemiplegia
Types I-IV, Diplegia, Triplegia and Quadriplegia. The GDI offers an alternative to the GGI as a comprehensive quantitative gait pathology index, and can be readily computed using the electronic addendum provided with this article.
Gait
Posture
2008 Oct
PMID:The Gait Deviation Index: a new comprehensive index of gait pathology. 1856 53
Rising from a chair or sit to stand (STS) is a movement with a great clinical interest: it is meaningful in order to evaluate motor control and stability in patients with functional limitations. STS requires some skills, as coordination between trunk and lower limbs movements, correction of muscles strength, control of equilibrium and stability and it is often considered into clinical evaluation scales of different pathologies. In literature, although some studies are focused on STS, the essential functions of standing up are not well standardized and uniformly defined: for this reason its application in clinical centres is difficult. In this study an experimental set-up for acquisition of STS movement which is suitable for clinical applications has been proposed: first, it was studied in healthy subjects, to define a normative database of this specific motor task, then in pathological subjects (adults with
hemiplegia
), to quantify their functional limitation, using quantitative kinematic and kinetic parameters. The results showed that this experimental set-up is effective both in healthy and in pathological subjects; some significant parameters were identified and calculated in order to characterise and quantify the functional limitation of patients.
Gait
Posture
2008 Jul
PMID:Quantitative analysis of sit to stand movement: experimental set-up definition and application to healthy and hemiplegic adults. 1861 56
1
2
3
Next >>