Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018991 (hemiplegia)
 3,997 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The frequency of upper respiratory tract abnormalities was determined in a selected population of racing Thoroughbreds. The prevalence of pharyngeal lymphoid hyperplasia was 34.2%; left laryngeal hemiplegia was 1.8%; and epiglottic entrapment was 0.74%. Excluding pharyngeal lymphoid hyperplasia and tracheal exudate, 3.7% of the population examined had upper respiratory tract abnormalities.
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PMID:Endoscopic findings in the upper respiratory tract of 678 Thoroughbred racehorses. 203 10

Upper airway pressure was measured during maximal exercise in 10 Thoroughbred racehorses with naturally occurring upper airway obstruction. Left laryngeal hemiplegia and arytenoid chondropathy resulted in substantial increases (30-40 cm H2O) in inspiratory upper airway pressure (Pl), whereas complicated aryepiglottic entrapment and subepiglottic cysts produced only modest increases (15 cm H2O) in Pl. Uncomplicated aryepiglottic entrapment and grade IV pharyngeal lymphoid hyperplasia produced only slight increases (3-5 cm H2O). In general, surgical procedures restored airway pressures to within normal limits. Subtotal arytenoidectomy improved but did not normalize airway pressures in horses with arytenoid chondropathy. Pharyngeal lymphoid hyperplasia appeared to have little effect on upper airway function.
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PMID:Upper airway function during maximal exercise in horses with obstructive upper airway lesions. Effect of surgical treatment. 233 86

The authors report the brain findings in six cases of familial erythrophagocytic lymphohistiocytosis (FEL) and review the literature, focusing primarily on the neurologic and neuropathologic aspects. Clinically, the most common neurologic abnormalities in the six patients were stupor or coma and seizures, with hemiplegia and cranial nerve palsies. Neuropathologic changes were characterized by infiltration of the meninges by lymphocytes and histiocytes and perivascular lymphocytic cuffing and diffuse proliferation of histiocytes in the brain parenchyma. The severity of the brain involvement was variable. In the mildest case there was only meningeal involvement. More severely involved cases showed meningeal and perivascular infiltration of lymphoid cells in the brain. In the most severely involved cases, there was, in addition, diffuse cerebral infiltration by histiocytes accompanied by multifocal necrosis. Some cases showed disproportionately greater involvement of the brain than of the visceral organs. The authors conclude that "meningoencephalitis," histiocytic invasion, and necrotizing brain lesions are characteristic of FEL, although the mechanism of their production is not known. Frequent seizures and disseminated intravascular coagulopathy may be contributory.
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PMID:Neuropathology of familial erythrophagocytic lymphohistiocytosis: six cases and review of the literature. 669 35

A flexible fiberoptic endoscope was used to examine the upper respiratory tract of 479 horses and 41 (8.6%) had abnormalities. Pharyngeal lymphoid hyperplasia (PLH) was found in 141 horses (29.5%). Statistical analysis showed a relationship between the age of the horse and the prevalence of PLH. Sixteen (3.3%), 10 (2.1%), and 6 (1.3%), of the horses had laryngeal hemiplegia, epiglottic entrapment, and dorsal displacement of the soft palate, respectively. There was no association between the age of the horse and the prevalence of any of these abnormalities; nor was there a positive correlation between the prevalence of exercise-induced pulmonary hemorrhage and PLH or laryngeal hemiplegia.
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PMID:Endoscopic findings in the upper respiratory tract of 479 horses. 698 61

A 15-year-old female harbor seal (Phoca vitulina) was referred to the Nantes Veterinary School, Nantes, France, with a clinical history of anorexia, seizures, and left hemiplegia. Cerebrospinal fluid analysis revealed large numbers of neoplastic lymphoid cells. After injection of a contrast agent into the cerebrospinal space, radiographs demonstrated an asymmetry of the right lateral ventricle. Necropsy examination revealed a marked edema of the right frontal lobe, extending to the basal nuclei and thalamus in the brain. Histological examination of the brain revealed leptomeningeal lymphoma. Immunohistochemical labeling demonstrated that the neoplasm was of T-cell origin. No significant macroscopic or microscopic lesions were observed in the other organs examined, including lymphoid organs. This is the first report of primary leptomeningeal lymphoma in a harbor seal.
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PMID:Primary meningeal T-cell lymphoma in a harbor seal (Phoca vitulina). 1767 18