Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018991 (hemiplegia)
3,997 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Herein we report an adult case of pure yolk sac tumor with brain metastasis. The patient was a 37-year-old male who presented with indulation of his left scrotum for 10 months. The plain computerized tomographic (CT) scan on entry demonstrated tumor metastasis to his lung and liver and serum alpha-fetoprotein (AFP) level was 786 ng/ml. Five days after admission, he developed hemiplegia secondary to the cerebral metastasis and hemorrhage. After chemotherapy and operation of right-posterior lobectomy, PVB (cisplatinum, vinblastine, bleomycin) chemotherapy produced a complete remission and the elevated serum AFP was normalized. However, the second course of chemotherapy had to be discontinued because of drug-induced hepatitis. He died of massive tumor metastasis to his brain 6 months after craniotomy.
...
PMID:[Pure yolk sac tumor of the testis with brain metastasis: report of an adult case]. 138 96

Two cases of paratesticular rhabdomyosarcoma were reported. One was a 53-year-old male, who was admitted to the Hospital because of swelling of the scrotum, hemosputa, and complete left hemiplegia. Clinical diagnosis was testicular tumor with remote metastases to lung, brain, liver, and para-aortic lymph nodes. At operation, tumor of 340 g of the paratesticular appendage was removed. Pathological findings of the tumor revealed rhabdomyosarcoma of mixed pleomorphic and embryonal types. The other was a 32-year-old male, who was admitted to the Hospital because of left inguinal and scrotal masses. The patient had a history of bruise at the left inguinal region about 5 years prior to admission. An orchiectomy and an excision of the inguinal tumor were performed. Histologically, the tumor was rhabdomyosarcoma of pleomorphic type. Clinical and pathological features of this rare tumor were discussed with a review of literature.
...
PMID:Paratesticular rhabdomyosarcoma. 662 57