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Query: UMLS:C0018991 (hemiplegia)
 3,997 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

As a tool for the study of normal and pathological motor manifestations, the experimental models of motor alterations are discussed. Here, we present particularly the neural and ethological characteristics of experimental models as hemiplegia, akinesia, parkinsonism and epilepsy.
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PMID:[Neural and ethological relations in the evaluation of motor control changes. II. Experimental models]. 268 7

Animal models of neurological deficits are essential for the assessment of new therapeutic options. It has been suggested that rats are not as appropriate as primates for the symptomatic modelling of disease, but a large body of data argues against this view. Comparative analyses of movements in rats and primates show homology of many motor patterns across species. Advances have been made in identifying rat equivalents of akinesia, tremor, postural deficits and dyskinesia, which are relevant to Parkinson's disease. Rat models of hemiplegia, neglect and tactile extinction are useful in assessing the outcome of ischaemic or traumatic brain injury, and in monitoring the effects of therapeutic interventions. Studies in rodents that emphasize careful behavioural analysis should continue to be developed as effective and inexpensive models that complement studies in primates.
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PMID:Animal models of neurological deficits: how relevant is the rat? 1209 13

The neglect syndrome has been defined as a failure to report, respond or orient to novel or meaningful stimuli presented to the side opposite of a brain lesion when this failure can not be attributed to elemental sensory (e.g., hemianopia) or motor (hemiplegia) deficits. This failure to report, respond or orient can be induced by attentional, representation-memory, and intentional deficits. The four major intentional deficits that can be associated with neglect include, akinesia (body part, directional and hemispatial), impersistence, defective response inhibition and motor perseveration. In this article we define and discuss each of these intentional disorders, describe how to test patients for these disorders and the neuropsychological and pathophysiological mechanisms that might be associated with these disorders.
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PMID:Intentional neglect. 1476 1

A 57-year-old woman had transient right hemiplegia 2 days after physical stress. An electrocardiogram exhibited T-wave inversion with QT prolongation. An echocardiogram revealed akinesia of the entire left ventricle except for the basal region. Cranial computed tomography and transthoracic echocardiography revealed an apical thrombus that disappeared 1 month later. Coronary angiography was normal. After 3 months, left ventricular wall motion had completely normalized.
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PMID:Transient cerebral ischemic attack induced by transient left ventricular apical ballooning. 1552 76