Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018991 (hemiplegia)
 3,997 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The term lacuna or lacunar cavity defines the pathological lesion while the clinical pictures due to lacuna or lacunes are referred to as 'lacunar syndromes'. The lacunar syndromes include: (1) the typical lacunar syndromes or lacunar syndromes proper--pure motor hemiplegia, pure sensory stroke, ataxic hemiparesis including dysarthria and clumsy hand, sensorimotor stroke and abnormal movement syndromes, (2) reversible ischemic attacks (TIA and/or PTIA or RIND), (3) other clinical syndromes which may be due to lacunar lesions such as suprabulbar palsy; lacunar dementia, or subacute arteriosclerotic encephalopathy (or Binswanger's disease). The different clinical pictures are reviewed, some mechanisms underlying the lacunar lesion are briefly discussed and the old label 'small vessel diseases' in cases with lacunes is reconsidered.
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PMID:The lacunar syndromes. 269 95

Reciprocal inhibition of H reflexes in the forearm flexor muscles was examined in a group of 16 patients with writer's and other occupational cramps. The early disynaptic phase of reciprocal inhibition was normal. However, there was a reduction in the amount of later, presynaptic inhibition, when compared with age-matched normal subjects. Similar findings were seen in 2 patients with symptomatic hemidystonia in whom structural brain lesions were present. However, this reduction in presynaptic inhibition was not specific to patients with dystonia. In a further group of 13 patients with hemiparesis or hemiplegia due to stroke, abnormalities of both early and later phases of reciprocal inhibition were found. The patients with spasticity exhibited less disynaptic inhibition than those with normal tone or flaccid limbs. The changes in the presynaptic phase of reciprocal inhibition did not correlate with the clinical signs of spasticity and increased muscle tone. These results provide objective evidence of a physiological basis for the action or task-specific focal dystonias such as writer's cramp.
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PMID:Reciprocal inhibition between forearm muscles in patients with writer's cramp and other occupational cramps, symptomatic hemidystonia and hemiparesis due to stroke. 273 Oct 27

A previously healthy 46-year-old woman had the abrupt onset of aphasia and right hemiplegia from a large left-hemisphere infarct. At postmortem examination the cause of the infarct was dissection and occlusion of the intracranial carotid artery. No preexisting abnormality was found to account for the dissection. This uncommon cause of stroke and its pathogenesis are discussed.
Stroke 1989 Aug
PMID:Spontaneous intracranial carotid artery dissection. 275 44

The purpose of this case report is to demonstrate the use of gait analysis and computer-assisted visual and auditory feedback (CAF) in the treatment of a patient with stroke secondary to hemiplegia. Two-dimensional kinematic and kinetic gait analyses were performed to determine the objectives of treatment and to evaluate the results. The CAF hardware and software permitted immediate visual feedback of performance relative to the desired target with auditory reinforcement if the target was reached in the desired phase of the gait cycle. The objective of the treatment was to increase knee flexion during push-off and pull-off. After four weekly treatments, the patient's gait velocity and stride length, in addition to transfers between kinetic energy and potential energy, were significantly improved. The patient demonstrated a downward trend in total mechanical energy costs and an upward trend in the amount of energy conservation, as well as increased knee flexion. These promising results indicate a need for further research into the use of CAF as a tool in motor learning for rehabilitation.
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PMID:Joint angle feedback and biomechanical gait analysis in stroke patients: a case report. 278 Aug 12

Multichannel electrical stimulation was applied in 20 patients with hemiplegia secondary to stroke or head injury using a six-channel microprocessor stimulator-stride analyzer to restore independent gait and to reestablish a normal gait pattern in a two- to three-week therapy period. The therapy was followed up at every session by a stride analyzer incorporated into the stimulator. At the beginning and at the end of the therapy period, each subject's gait was measured with a ground reaction measuring system. Statistical results and observations are presented for the group of 20 subjects, and a detailed description of the results is given for one subject who is representative of the whole group. According to the measured gait characteristics, gait improved significantly in all subjects during the therapy period, resulting in a partly or completely independent gait. The subjects' posture and endurance also improved, and they spontaneously learned how to use a crutch. The measurements and visual assessment of the subjects' progress indicate that the described treatment protocol offers good prospects for faster and more efficient gait rehabilitation in severely impaired patients. To determine the efficacy of gait therapy with multichannel electrical stimulation, a comparative study of conventional therapeutic methods and the method described in this article should be conducted.
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PMID:Restoration of gait during two to three weeks of therapy with multichannel electrical stimulation. 278 73

We describe the clinical and anatomopathological findings in an 85-year-old male presenting with a lateral medullary syndrome and ipsilateral hemiplegia (Opalski's syndrome) due to giant-cell arteritis of the vertebral artery. Other common associated symptoms of the disease were absent, and the erythrocyte sedimentation rate was only of 30 mm/h. This case emphasizes that limited intracranial giant-cell arteritis may present rarely as a stroke.
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PMID:Giant-cell arteritis presenting with ipsilateral hemiplegia and lateral medullary syndrome. 279 45

The purpose of this study was to analyze how the locus of the sway of the center of gravity (LSCG) while standing could serve as a prognostic predictor of the hemiplegic's walking ability. It was demonstrated that the prognosis of the walking ability could be predicted by the size of LSCG while standing. The size of LSCG was based on the results of the rehabilitation of 33 stroke patients with hemiplegia. After rehabilitation treatment, LSCG was significantly small and its level was maintained for a short follow-up. In the deep sensory disturbance group, however, LSCG was still larger after treatment than that of the control group. LSCG was closely correlated with walking ability at admission and discharge. With regard to the predictable factor of the walking ability improvement rate, four important factors in the following order were able to be determined by using multivariate analysis: Walking ability at admission, duration of illness, LSCG with eyes opened at admission and the rate of visual suppression (% VS). Furthermore, with respect to the predictable factor of walking ability at discharge, the following four factors, were able to be concluded: duration of illness, LSCG with eyes opened, % VS and Barthel Index Score (BIS) at the time of admission. It is therefore suggested that LSCG can make it possible to predict the walking ability, i.e., the improvement and the quality of it.
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PMID:Rehabilitation of post-stroke hemiplegic patients. I. Gravity-center-swaying and walking ability. 281 62

Hypoglycemia can result in a transient hemiplegia mimicking a minor cerebral vascular accident. With the widespread use of oral hypoglycemics and insulin this unexpected presentation of hypoglycemia is now being reported more frequently in the medical literature. This article describes a case of hypoglycemic hemiparesis and illustrates the need to consider this diagnosis, especially when the diabetic patient presents with stroke-like symptoms.
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PMID:[Hypoglycemic hemiparesis. A case report]. 281 7

In 368 patients with residual hemiplegia after stroke, monitoring of recovery over eight weeks showed a distinct time-related pattern. Patterns of this sort could provide useful baselines in various conditions entailing physical disability, allowing comparison of individual scores with the average for that phase of the illness, the setting of precise goals, and the examination of factors that influence recovery.
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PMID:Recovery from physical disability after stroke: normal patterns as a basis for evaluation. 288 Jan 73

The purpose of this study was to describe and compare the gait of 20 patients with hemiplegia secondary to cerebrovascular accident (CVA) before and after a treatment regimen of resisted pelvic motions. Ten women and 10 men were studied, with a mean age of 48 years and a mean duration post-CVA of two months. Nine subjects (45%) were right hemiplegic, and 11 subjects (55%) were left hemiplegic. Treatment consisted of four sets of five repetitions each of manually resisted pelvic anterior-elevation and posterior-depression movements on the involved side. An insole footswitch system, knee electrogoniometer, and force walking aid were used in gait analysis performed before treatment, immediately after treatment (posttest 1), and 30 minutes after treatment (posttest 2). Results showed significant overall improvement in gait in posttest 1 (p less than .005) compared with the pretest. This improvement, however, was not maintained in posttest 2. Ten patients improved overall in posttest 1; only 4 patients also showed improvement in posttest 2. The major improvements seen immediately after treatment were observed in stance stability and limb advancement in the involved limb. More research is needed to identify an optimum treatment with carry-over using this technique.
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PMID:Pelvic exercise and gait in hemiplegia. 291 13


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