Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018991 (hemiplegia)
 3,997 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Emergency revascularization procedures for patients with acute stroke are controversial. Thirty-four patients with acute internal carotid artery occlusion documented at the time of emergency endarterectomy were analyzed. Before operation, all these patients had profound neurological deficits including hemiplegia and aphasia. There was a 94% success rate in restoring patency. In follow-up, nine patients (26.5%) had a normal neurological exam, four (11.8%) had a minimal deficit, 10 (29.4%) had a moderate hemiparesis, which was improved over their preoperative deficit, 4 (11.8%) remained hemiplegic, and seven (20.6%) died. The natural history of patients with acute carotid occlusion and profound neurological deficits is dismal. In comparison, 13 patients (38%) made a dramatic recovery. The surgical mortality rate compares favorably with the natural history. Good collateral flow was a good prognostic factor, while a simultaneous middle cerebral artery embolus was associated with a poorer prognosis. An emergency carotid endarterectomy may be indicated in selected patients with acute internal carotid artery occlusion with profound neurological deficits. Full preoperative angiography may identify those patients who would benefit from surgical intervention and reduce the operative mortality rate.
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PMID:Emergency carotid endarterectomy for patients with acute carotid occlusion and profound neurological deficits. 394 24

A case of a acoustic neuroma with a two-stage removal due to severe bleeding is presented. The patient remained drowsy after the second operation and by the 8th day deteriorated quickly with progressive right hemiplegia and aphasia. The cerebrospinal fluid was bloody, vasospasm was shown in the angiograms, and an ischemic area was disclosed in the computed tomography scan. The outcome and the neuroradiologic examinations suggested that blood in the basal cisterns caused the vasospasm and the brain ischemia. A review of the literature disclosed only one similar case.
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PMID:Vasospasm after acoustic neuroma removal. 396 76

The authors present two cases of transient occlusion of the major cerebral arteries which occurred during transfemoral catheterization of the carotid artery. Right hemiplegia and aphasia developed suddenly in both cases, and disappeared completely within 14 hours in one case and 25 minutes in the other. On the angiograms performed at the moment of onset of the symptoms, the site of the occlusion was the left internal carotid artery in one case and the left middle cerebral artery in the other. Angiograms which were repeated soon after clinical improvement revealed complete dissolution of the occluding emboli. These cases present direct radiographic evidence that embolic occlusion of a major cerebral artery and its disappearance is the mechanism of the transient manifestation of the neurological deficits associated with cerebrovascular catheterization.
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PMID:Transient neurological deficits due to embolic occlusion and immediate reopening of the cerebral arteries. 400 71

In three cases, there was an injury of primary carotid artery, and in one case a wound of bifurcation with a large destruction of vessels. In one, there was an A.V. fistula as shoot by the pre of angiogram. Only one patient was in light coma with right hemiplegia and aphasia. Repair was done with a simple suture in one, with a resection and a suture in an other. In two cases an inversed venous grafting was done. In all 4 cases results were satisfactory without any neurologic sequellae.
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PMID:[Bullet wounds of the carotid axis. Apropos of 4 cases]. 404 93

A 24-year-old woman with a left-sided cerebral infarction presented with hemiplegia and aphasia. Five months earlier she had had a closed head injury. Angiography revealed bilateral extracranial post-traumatic aneurysms of the internal carotid artery at the atlanto-axial level. There was full recovery without operative treatment within a week.
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PMID:Bilateral traumatic extracranial aneurysms of the internal carotid artery with delayed brain infarction. 405 39

Three patients with severe aphasia and right hemiplegia are described who could write to dictation with the right arm using a limb prosthesis though agraphic with the "intact" left hand. The phenomenon of "hemiplegic writing" is explained as an access to submerged or preprocessing levels in language and action structure, through the use of older proximal motor systems. This interpretation has implications for our understanding of language and brain function, as well as for approaches to the treatment of patients with severe language disorders.
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PMID:Hemiplegic writing in severe aphasia. 619 67

We studied a case of language loss caused by an acquired vascular lesion in the putamen, anterior limb of the internal capsule, and lateral aspect of the head of the caudate nucleus in a 7-year-old right-handed girl. Acute right-sided hemiplegia, mutism, oral apraxia, and disturbance in language comprehension but no dysarthria were present. During recovery, a nonfluent aphasia with anomia was evident. After six months, only mild hemiparesis and minor spelling difficulties persisted. We compared this patient with an 11-year-old right-handed girl with right-sided hemiparesis and dysarthria but no language loss following a lesion in the globus pallidus, a portion of the posterior limb of the internal capsule, and the body of the caudate. The presence of a language disturbance in the first but not the second patient was attributed to the difference in lesion location. The symptoms and lesions were similar to those in recent reports of adult patients. To our knowledge, this is the first report of these findings in a child with a left-hemisphere lesion.
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PMID:Acquired capsular/striatal aphasia in childhood. 619 70

We report a case of aphasia and right hemiplegia, developing after myelography with metrizamide and lasting for an unusually long time. The neurological disorders, manifested 1 h after the examination was completed, were due to accidental passage of contrast medium into the basal cisterns. In the light of analogous case reports in the literature, as well as experimental data concerning the biochemical activity of metrizamide, possible aetiopathogenetic mechanisms responsible for such disturbances are indicated. The authors underline the lack of effective therapeutic measures after the onset of the disorders, and thus the importance of preventing such complications that behave functionally as true ictuses although with no anatomic substratum.
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PMID:Aphasia and right hemiplegia after cervical myelography with metrizamide. A case report. 620 49

Ten patients with ischaemic stroke were treated with prostacyclin (2.5-5.0 ng/kg/min i.v. in 6 h courses 4-10 times during 1-2.5 days). In all patients a dramatic regression of hemiplegia, or hemiparesis, or aphasia occurred in the first few hours of prostacyclin infusion. Four to eight weeks later 6 patients left the clinic without neurological deficit; 3 patients had minor residual hemiparesis in upper limbs. In one patient, the occlusion of the contralateral carotid artery led to his death. It is considered that an antagonism may exist between endogenous cerebral prostanoids and prostacyclin and may have been responsible for the beneficial effects of prostacyclin therapy.
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PMID:Treatment of ischaemic stroke with prostacyclin. 634 Feb 53

A total, primitive, persistent, non-familial auricular standstill was observed in a twenty-two year old female with right hemiplegia and aphasia. The diagnosis was confirmed by electrocardiogram, fluoroscopy, echocardiography and intra-atrial recording and pacing. The patient was treated with permanent pacemaker and anticoagulant drugs. The various clinical presentations, diagnostic criteria, and therapeutic choices are reviewed.
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PMID:[Persistent atrial paralysis. Observation of a clinical case and review of the literature]. 639 98


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