Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018801 (
heart failure
)
72,216
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4523
renin
2521
natriuretic peptide
2465
Mol
2334
angiotensin II
1501
insulin
1206
ACE
1164
collagen
1045
She
826
angiotensin receptor
792
Mal
767
ATP
729
cytokine
725
atrial natriuretic peptide
650
Ang II
641
BNP
624
ATPase
623
cardiac muscle
599
hemoglobin
547
phosphodiesterase
508
mineralocorticoid receptor
498
calcium channel
481
vasopressin
474
neutral endopeptidase
431
tumor necrosis factor
412
C-reactive protein
402
Pol
378
MRI
372
myosin
368
angiotensin II receptor
357
atrial natriuretic factor
331
phospholamban
326
albumin
312
TNF
309
endothelin-1
295
nitric oxide synthase
283
creatine kinase
276
chronic renal failure
267
IL-6
263
Angiotensin-converting enzyme
251
ryanodine receptor
251
endoplasmic reticulum
250
bradykinin
244
calcineurin
243
caspase-3
235
beta 1
234
ICD
233
AT1
229
sarcomeric
228
ANP
223
p38
210
myosin heavy chain
208
troponin I
199
interleukin-6
194
superoxide dismutase
193
erythropoietin
191
Bcl-2
190
RyR2
188
calmodulin
187
gut
186
galectin-3
183
matrix metalloproteinase
183
vascular endothelial growth factor
182
thyroid hormone
175
reserved
173
ERK1
169
glucagon
164
transthyretin
163
adenylyl cyclase
161
TNF-alpha
157
arginine vasopressin
157
COPD
157
Renin
157
peptidase
153
growth hormone
151
AMP
151
p53
150
histone
149
MAPK
146
mTOR
146
more...
Disease
heart failure
72216
hypertension
8321
myocardial infarction
6961
diabetes
4722
congestive heart failure
4712
stroke
4603
cardiomyopathy
4298
cardiovascular disease
3361
heart disease
3221
coronary artery disease
2951
dilated cardiomyopathy
2738
myocardial ischemia
2676
acute myocardial infarction
2469
ischemia
2040
cancer
1999
atherosclerosis
1677
pulmonary hypertension
1515
obesity
1483
ventricular hypertrophy
1461
myocarditis
1315
coronary heart disease
1230
renal failure
1186
mitral regurgitation
1185
depression
1115
anemia
1056
type 2 diabetes
1000
renal disease
960
endocarditis
928
tumor
886
chronic obstructive pulmonary disease
881
hypertrophic cardiomyopathy
817
sepsis
799
sepsis
731
pulmonary edema
719
aortic stenosis
663
pneumonia
654
ischemic cardiomyopathy
577
idiopathic dilated cardiomyopathy
543
aortic regurgitation
538
ventricular fibrillation
537
cirrhosis
501
pulmonary embolism
470
right heart failure
463
left ventricular failure
462
amyloidosis
461
respiratory failure
443
sleep apnea
443
valvular heart disease
438
diabetic cardiomyopathy
429
pericarditis
419
chronic renal failure
399
metabolic syndrome
394
atrioventricular block
392
renal insufficiency
377
left bundle branch block
371
asthma
371
vascular disease
369
ventricular dilatation
366
essential hypertension
347
unstable angina
345
ventricular septal defect
338
tricuspid regurgitation
336
obstructive sleep apnea
329
pericardial effusion
322
dyslipidemia
318
chronic disease
304
Chronic heart failure
295
myopathy
294
hyperlipidemia
294
hyperglycemia
293
dementia
287
Chagas
277
proteinuria
277
malnutrition
274
fluid overload
271
renal impairment
270
breast cancer
248
plaque
244
hypertensive heart disease
238
liver disease
237
more...
Symptom
dyspnea
1779
angina
1539
fatigue
735
chest pain
574
regurgitation
558
anesthesia
558
pain
525
syncope
445
weakness
368
respiratory distress
320
cachexia
296
cough
289
shortness of breath
269
collapse
228
cyanosis
228
exertional dyspnea
201
headache
199
overweight
183
seizures
168
diarrhea
164
vomiting
153
dizziness
150
hypothermia
146
CSR
143
hepatomegaly
140
nausea
134
thinning
133
abdominal pain
128
functional recovery
125
anorexia
119
discomfort
110
discomfort
102
orthopnea
101
hypercapnia
100
sleepiness
98
rales
89
exhaustion
85
starvation
69
hemoptysis
67
Ill
65
tachypnea
64
spasm
64
leg edema
59
splenomegaly
53
oliguria
50
insomnia
46
hypotonia
45
constipation
44
lethargy
44
arthralgia
43
snoring
43
back pain
42
flushing
39
myalgia
39
nausea and vomiting
39
Exercise intolerance
38
hepatosplenomegaly
38
analgesia
36
agitation
36
tremor
35
hypocapnia
32
ataxia
32
exertional angina
31
vertigo
30
asynergy
30
erythema
26
polyuria
25
acute stress
24
hypoproteinemia
24
low back pain
23
presyncope
23
pallor
22
atypical chest pain
22
chills
21
paresis
21
hemiplegia
20
wheezing
19
hyperoxia
19
asthenia
18
epigastric pain
17
more...
Drug
Cardiovasc
5111
nitroglycerin
290
Angiotensin II
241
Monit
176
Levosimendan
166
Digitalis
149
ROS
145
Captopril
143
Dial
142
Nephron
106
caffeine
104
ROC
101
Valsartan
92
Nesiritide
87
lysine
83
Tolvaptan
81
Fraction
71
NADH
68
Ramipril
66
MAP
64
Dermatol
62
ETA
52
Spectrum
51
Perindopril
51
ICI
51
vitamin E
47
Adriamycin
46
ascorbate
46
Herceptin
43
Nebivolol
42
Enoximone
41
Amrinone
40
CSF
40
AHF
39
Dronedarone
36
Glucagon
33
Ranolazine
32
Ibopamine
32
Ranolazine
32
Nephron
31
TAC
31
IL-2
30
Aliskiren
30
Flosequinan
29
Growth hormone
29
Growth hormone
29
Ouabain
27
Omapatrilat
26
Nitric Oxide
26
Vesnarinone
25
Dakar
24
ampicillin
22
CTX
22
Pimobendan
22
ADM
22
Propofol
21
Rosuvastatin
20
Rosiglitazone
20
Clopidogrel
19
Torasemide
19
Ethanol
18
EPI
18
Sodium nitroprusside
18
PTH
17
APD
17
Bosentan
16
Simvastatin
16
Bosentan
16
G-CSF
15
Serum albumin
15
Atenolol
15
Vitamin E
15
Liraglutide
15
Conivaptan
15
Ginseng
14
Gel
14
Asthma
14
citric acid
14
Albumin
13
Indomethacin
13
more...
Enzyme
renin
2521
ACE
1848
ATPase
676
protein kinase
673
mitogen-activated protein kinase
525
phosphodiesterase
509
CD10
456
creatine kinase
362
ERK
303
calcineurin
261
superoxide dismutase
238
protein kinase C
220
NADPH oxidase
197
caspase-3
177
NO synthase
164
AMP-activated protein kinase
155
NADPH oxidase
152
proteasome
147
lactate dehydrogenase
144
guanylate cyclase
139
adenylate cyclase
132
catalase
123
luciferase
117
CaMKII
109
GRK2
103
xanthine oxidase
103
AMPK
100
GRK5
98
focal adhesion kinase
95
glutathione peroxidase
94
peroxidase
82
ACS
76
thrombin
74
AMPK
71
complex I
68
PDE
68
aspartate aminotransferase
66
MEK
65
tissue plasminogen activator
63
PKG
63
NOS
61
alkaline phosphatase
60
MAP
59
CAD
58
CAD
58
CAD
58
collagenase
57
alanine aminotransferase
56
phosphoinositide 3-kinase
55
thromboplastin
52
citrate synthase
48
GSK
47
reverse transcriptase
47
pyruvate dehydrogenase
47
APC
45
PARP
45
acetylcholinesterase
41
urokinase-type plasminogen activator
41
phosphatidylinositol 3-kinase
41
tyrosine hydroxylase
39
pyruvate dehydrogenase
38
angiotensin-converting enzyme 2
38
pyruvate dehydrogenase
38
calcium pump
37
succinate dehydrogenase
37
glyceraldehyde-3-phosphate dehydrogenase
37
kallikrein
36
CPT
36
chymase
35
caspase-1
34
endothelin-converting enzyme
32
PDK1
31
myosin ATPase
30
aldehyde dehydrogenase
30
phospholipase C
30
cytochrome oxidase
29
MMP
28
caspase-8
28
ATP synthase
25
acyl-CoA dehydrogenase
25
more...
Compound
Cardiol
9993
Clin
5303
Dec
4878
oxygen
3400
calcium
3020
sodium
2225
aldosterone
2085
glucose
1514
acetate
1287
nitric oxide
1160
water
1129
creatinine
1002
potassium
942
DNA
809
ATP
730
salt
676
BNP
611
Angiotensin II
566
iron
563
His
446
CO2
423
cAMP
393
noradrenaline
389
Ang II
354
phosphate
351
arginine
328
cGMP
326
TNF
309
urea
259
nitrogen
228
Digoxin
222
nitrate
210
Carvedilol
204
serine
176
hydrogen
172
Sodium
163
AMP
162
Optimal
158
GMP
153
ADP
153
Adriamycin
151
tyrosine
150
Dial
145
vitamin D
144
Amiodarone
141
Insulin
141
ADP
134
ADP
130
ethanol
129
iodine
128
phosphocreatine
128
Isoproterenol
124
Spironolactone
120
ADR
119
cysteine
119
threonine
116
ASA
115
Hearts
114
Hearts
111
Dobutamine
110
prostacyclin
110
Thyroid
109
lysine
104
caffeine
104
NAD
98
Enalapril
96
Losartan
93
sulfate
93
coenzyme Q10
92
DCM
92
AHA
90
Metoprolol
89
homocysteine
87
Eplerenone
85
Pac
84
zinc
83
Metoprolol
83
NAD
82
DDD
78
ACS
75
more...