Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018801 (heart failure)
72,216 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4523
renin 2521
natriuretic peptide 2465
Mol 2334
angiotensin II 1501
insulin 1206
ACE 1164
collagen 1045
She 826
angiotensin receptor 792
Mal 767
ATP 729
cytokine 725
atrial natriuretic peptide 650
Ang II 641
BNP 624
ATPase 623
cardiac muscle 599
hemoglobin 547
phosphodiesterase 508
mineralocorticoid receptor 498
calcium channel 481
vasopressin 474
neutral endopeptidase 431
tumor necrosis factor 412
C-reactive protein 402
Pol 378
MRI 372
myosin 368
angiotensin II receptor 357
atrial natriuretic factor 331
phospholamban 326
albumin 312
TNF 309
endothelin-1 295
nitric oxide synthase 283
creatine kinase 276
chronic renal failure 267
IL-6 263
Angiotensin-converting enzyme 251
ryanodine receptor 251
endoplasmic reticulum 250
bradykinin 244
calcineurin 243
caspase-3 235
beta 1 234
ICD 233
AT1 229
sarcomeric 228
ANP 223
p38 210
myosin heavy chain 208
troponin I 199
interleukin-6 194
superoxide dismutase 193
erythropoietin 191
Bcl-2 190
RyR2 188
calmodulin 187
gut 186
galectin-3 183
matrix metalloproteinase 183
vascular endothelial growth factor 182
thyroid hormone 175
reserved 173
ERK1 169
glucagon 164
transthyretin 163
adenylyl cyclase 161
TNF-alpha 157
arginine vasopressin 157
COPD 157
Renin 157
peptidase 153
growth hormone 151
AMP 151
p53 150
histone 149
MAPK 146
mTOR 146
more...
Disease
heart failure 72216
hypertension 8321
myocardial infarction 6961
diabetes 4722
congestive heart failure 4712
stroke 4603
cardiomyopathy 4298
cardiovascular disease 3361
heart disease 3221
coronary artery disease 2951
dilated cardiomyopathy 2738
myocardial ischemia 2676
acute myocardial infarction 2469
ischemia 2040
cancer 1999
atherosclerosis 1677
pulmonary hypertension 1515
obesity 1483
ventricular hypertrophy 1461
myocarditis 1315
coronary heart disease 1230
renal failure 1186
mitral regurgitation 1185
depression 1115
anemia 1056
type 2 diabetes 1000
renal disease 960
endocarditis 928
tumor 886
chronic obstructive pulmonary disease 881
hypertrophic cardiomyopathy 817
sepsis 799
sepsis 731
pulmonary edema 719
aortic stenosis 663
pneumonia 654
ischemic cardiomyopathy 577
idiopathic dilated cardiomyopathy 543
aortic regurgitation 538
ventricular fibrillation 537
cirrhosis 501
pulmonary embolism 470
right heart failure 463
left ventricular failure 462
amyloidosis 461
respiratory failure 443
sleep apnea 443
valvular heart disease 438
diabetic cardiomyopathy 429
pericarditis 419
chronic renal failure 399
metabolic syndrome 394
atrioventricular block 392
renal insufficiency 377
left bundle branch block 371
asthma 371
vascular disease 369
ventricular dilatation 366
essential hypertension 347
unstable angina 345
ventricular septal defect 338
tricuspid regurgitation 336
obstructive sleep apnea 329
pericardial effusion 322
dyslipidemia 318
chronic disease 304
Chronic heart failure 295
myopathy 294
hyperlipidemia 294
hyperglycemia 293
dementia 287
Chagas 277
proteinuria 277
malnutrition 274
fluid overload 271
renal impairment 270
breast cancer 248
plaque 244
hypertensive heart disease 238
liver disease 237
more...
Symptom
dyspnea 1779
angina 1539
fatigue 735
chest pain 574
regurgitation 558
anesthesia 558
pain 525
syncope 445
weakness 368
respiratory distress 320
cachexia 296
cough 289
shortness of breath 269
collapse 228
cyanosis 228
exertional dyspnea 201
headache 199
overweight 183
seizures 168
diarrhea 164
vomiting 153
dizziness 150
hypothermia 146
CSR 143
hepatomegaly 140
nausea 134
thinning 133
abdominal pain 128
functional recovery 125
anorexia 119
discomfort 110
discomfort 102
orthopnea 101
hypercapnia 100
sleepiness 98
rales 89
exhaustion 85
starvation 69
hemoptysis 67
Ill 65
tachypnea 64
spasm 64
leg edema 59
splenomegaly 53
oliguria 50
insomnia 46
hypotonia 45
constipation 44
lethargy 44
arthralgia 43
snoring 43
back pain 42
flushing 39
myalgia 39
nausea and vomiting 39
Exercise intolerance 38
hepatosplenomegaly 38
analgesia 36
agitation 36
tremor 35
hypocapnia 32
ataxia 32
exertional angina 31
vertigo 30
asynergy 30
erythema 26
polyuria 25
acute stress 24
hypoproteinemia 24
low back pain 23
presyncope 23
pallor 22
atypical chest pain 22
chills 21
paresis 21
hemiplegia 20
wheezing 19
hyperoxia 19
asthenia 18
epigastric pain 17
more...
Drug
Cardiovasc 5111
nitroglycerin 290
Angiotensin II 241
Monit 176
Levosimendan 166
Digitalis 149
ROS 145
Captopril 143
Dial 142
Nephron 106
caffeine 104
ROC 101
Valsartan 92
Nesiritide 87
lysine 83
Tolvaptan 81
Fraction 71
NADH 68
Ramipril 66
MAP 64
Dermatol 62
ETA 52
Spectrum 51
Perindopril 51
ICI 51
vitamin E 47
Adriamycin 46
ascorbate 46
Herceptin 43
Nebivolol 42
Enoximone 41
Amrinone 40
CSF 40
AHF 39
Dronedarone 36
Glucagon 33
Ranolazine 32
Ibopamine 32
Ranolazine 32
Nephron 31
TAC 31
IL-2 30
Aliskiren 30
Flosequinan 29
Growth hormone 29
Growth hormone 29
Ouabain 27
Omapatrilat 26
Nitric Oxide 26
Vesnarinone 25
Dakar 24
ampicillin 22
CTX 22
Pimobendan 22
ADM 22
Propofol 21
Rosuvastatin 20
Rosiglitazone 20
Clopidogrel 19
Torasemide 19
Ethanol 18
EPI 18
Sodium nitroprusside 18
PTH 17
APD 17
Bosentan 16
Simvastatin 16
Bosentan 16
G-CSF 15
Serum albumin 15
Atenolol 15
Vitamin E 15
Liraglutide 15
Conivaptan 15
Ginseng 14
Gel 14
Asthma 14
citric acid 14
Albumin 13
Indomethacin 13
more...
Enzyme
renin 2521
ACE 1848
ATPase 676
protein kinase 673
mitogen-activated protein kinase 525
phosphodiesterase 509
CD10 456
creatine kinase 362
ERK 303
calcineurin 261
superoxide dismutase 238
protein kinase C 220
NADPH oxidase 197
caspase-3 177
NO synthase 164
AMP-activated protein kinase 155
NADPH oxidase 152
proteasome 147
lactate dehydrogenase 144
guanylate cyclase 139
adenylate cyclase 132
catalase 123
luciferase 117
CaMKII 109
GRK2 103
xanthine oxidase 103
AMPK 100
GRK5 98
focal adhesion kinase 95
glutathione peroxidase 94
peroxidase 82
ACS 76
thrombin 74
AMPK 71
complex I 68
PDE 68
aspartate aminotransferase 66
MEK 65
tissue plasminogen activator 63
PKG 63
NOS 61
alkaline phosphatase 60
MAP 59
CAD 58
CAD 58
CAD 58
collagenase 57
alanine aminotransferase 56
phosphoinositide 3-kinase 55
thromboplastin 52
citrate synthase 48
GSK 47
reverse transcriptase 47
pyruvate dehydrogenase 47
APC 45
PARP 45
acetylcholinesterase 41
urokinase-type plasminogen activator 41
phosphatidylinositol 3-kinase 41
tyrosine hydroxylase 39
pyruvate dehydrogenase 38
angiotensin-converting enzyme 2 38
pyruvate dehydrogenase 38
calcium pump 37
succinate dehydrogenase 37
glyceraldehyde-3-phosphate dehydrogenase 37
kallikrein 36
CPT 36
chymase 35
caspase-1 34
endothelin-converting enzyme 32
PDK1 31
myosin ATPase 30
aldehyde dehydrogenase 30
phospholipase C 30
cytochrome oxidase 29
MMP 28
caspase-8 28
ATP synthase 25
acyl-CoA dehydrogenase 25
more...
Compound
Cardiol 9993
Clin 5303
Dec 4878
oxygen 3400
calcium 3020
sodium 2225
aldosterone 2085
glucose 1514
acetate 1287
nitric oxide 1160
water 1129
creatinine 1002
potassium 942
DNA 809
ATP 730
salt 676
BNP 611
Angiotensin II 566
iron 563
His 446
CO2 423
cAMP 393
noradrenaline 389
Ang II 354
phosphate 351
arginine 328
cGMP 326
TNF 309
urea 259
nitrogen 228
Digoxin 222
nitrate 210
Carvedilol 204
serine 176
hydrogen 172
Sodium 163
AMP 162
Optimal 158
GMP 153
ADP 153
Adriamycin 151
tyrosine 150
Dial 145
vitamin D 144
Amiodarone 141
Insulin 141
ADP 134
ADP 130
ethanol 129
iodine 128
phosphocreatine 128
Isoproterenol 124
Spironolactone 120
ADR 119
cysteine 119
threonine 116
ASA 115
Hearts 114
Hearts 111
Dobutamine 110
prostacyclin 110
Thyroid 109
lysine 104
caffeine 104
NAD 98
Enalapril 96
Losartan 93
sulfate 93
coenzyme Q10 92
DCM 92
AHA 90
Metoprolol 89
homocysteine 87
Eplerenone 85
Pac 84
zinc 83
Metoprolol 83
NAD 82
DDD 78
ACS 75
more...