Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018801 (
heart failure
)
72,216
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4523
renin
2521
natriuretic peptide
2465
Mol
2334
angiotensin II
1501
insulin
1206
ACE
1164
collagen
1045
She
826
angiotensin receptor
792
Mal
767
ATP
729
cytokine
725
atrial natriuretic peptide
650
Ang II
641
BNP
624
ATPase
623
cardiac muscle
599
hemoglobin
547
phosphodiesterase
508
mineralocorticoid receptor
498
calcium channel
481
vasopressin
474
neutral endopeptidase
431
tumor necrosis factor
412
C-reactive protein
402
Pol
378
MRI
372
myosin
368
angiotensin II receptor
357
atrial natriuretic factor
331
phospholamban
326
albumin
312
TNF
309
endothelin-1
295
nitric oxide synthase
283
creatine kinase
276
chronic renal failure
267
IL-6
263
ryanodine receptor
251
more...
Disease
heart failure
72216
hypertension
8321
myocardial infarction
6961
diabetes
4722
congestive heart failure
4712
stroke
4603
cardiomyopathy
4298
cardiovascular disease
3361
heart disease
3221
coronary artery disease
2951
dilated cardiomyopathy
2738
myocardial ischemia
2676
acute myocardial infarction
2469
ischemia
2040
cancer
1999
atherosclerosis
1677
pulmonary hypertension
1515
obesity
1483
ventricular hypertrophy
1461
myocarditis
1315
coronary heart disease
1230
renal failure
1186
mitral regurgitation
1185
depression
1115
anemia
1056
type 2 diabetes
1000
renal disease
960
endocarditis
928
tumor
886
chronic obstructive pulmonary disease
881
hypertrophic cardiomyopathy
817
sepsis
799
sepsis
731
pulmonary edema
719
aortic stenosis
663
pneumonia
654
ischemic cardiomyopathy
577
idiopathic dilated cardiomyopathy
543
aortic regurgitation
538
ventricular fibrillation
537
more...
Symptom
dyspnea
1779
angina
1539
fatigue
735
chest pain
574
regurgitation
558
anesthesia
558
pain
525
syncope
445
weakness
368
respiratory distress
320
cachexia
296
cough
289
shortness of breath
269
collapse
228
cyanosis
228
exertional dyspnea
201
headache
199
overweight
183
seizures
168
diarrhea
164
vomiting
153
dizziness
150
hypothermia
146
CSR
143
hepatomegaly
140
nausea
134
thinning
133
abdominal pain
128
functional recovery
125
anorexia
119
discomfort
110
discomfort
102
orthopnea
101
hypercapnia
100
sleepiness
98
rales
89
exhaustion
85
starvation
69
hemoptysis
67
Ill
65
more...
Drug
Cardiovasc
5111
nitroglycerin
290
Angiotensin II
241
Monit
176
Levosimendan
166
Digitalis
149
ROS
145
Captopril
143
Dial
142
Nephron
106
caffeine
104
ROC
101
Valsartan
92
Nesiritide
87
lysine
83
Tolvaptan
81
Fraction
71
NADH
68
Ramipril
66
MAP
64
Dermatol
62
ETA
52
Perindopril
51
ICI
51
Spectrum
51
vitamin E
47
ascorbate
46
Adriamycin
46
Herceptin
43
Nebivolol
42
Enoximone
41
CSF
40
Amrinone
40
AHF
39
Dronedarone
36
Glucagon
33
Ranolazine
32
Ranolazine
32
Ibopamine
32
TAC
31
more...
Enzyme
renin
2521
ACE
1848
ATPase
676
protein kinase
673
mitogen-activated protein kinase
525
phosphodiesterase
509
CD10
456
creatine kinase
362
ERK
303
calcineurin
261
superoxide dismutase
238
protein kinase C
220
NADPH oxidase
197
caspase-3
177
NO synthase
164
AMP-activated protein kinase
155
NADPH oxidase
152
proteasome
147
lactate dehydrogenase
144
guanylate cyclase
139
adenylate cyclase
132
catalase
123
luciferase
117
CaMKII
109
GRK2
103
xanthine oxidase
103
AMPK
100
GRK5
98
focal adhesion kinase
95
glutathione peroxidase
94
peroxidase
82
ACS
76
thrombin
74
AMPK
71
complex I
68
PDE
68
aspartate aminotransferase
66
MEK
65
PKG
63
tissue plasminogen activator
63
more...
Compound
Cardiol
9993
Clin
5303
Dec
4878
oxygen
3400
calcium
3020
sodium
2225
aldosterone
2085
glucose
1514
acetate
1287
nitric oxide
1160
water
1129
creatinine
1002
potassium
942
DNA
809
ATP
730
salt
676
BNP
611
Angiotensin II
566
iron
563
His
446
CO2
423
cAMP
393
noradrenaline
389
Ang II
354
phosphate
351
arginine
328
cGMP
326
TNF
309
urea
259
nitrogen
228
Digoxin
222
nitrate
210
Carvedilol
204
serine
176
hydrogen
172
Sodium
163
AMP
162
Optimal
158
ADP
153
GMP
153
more...