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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Heart failure is a common and increasing public problem. Neurohormonal activation plays a role in the pathophysiology of heart failure, but is probably also affected by cytokines. We studied 75 patients with heart failure NYHA functional class II and III-IV, who were treated with angiotensin converting enzyme inhibitor (enarenal), diuretics (furosemide) and digoxine. Their mean age was 63.9 years/range 65-86/, left ventricular ejection fraction in the patients NYHA functional class II and III-IV classes was 68.9% and 47.3% respectively; 12 were females. Significant improvements in NYHA classification were shown. The levels plasma TNF-alpha (tumor necrosis factor-alpha) and interleukin-6 (IL-6) were analysed before and after therapy. The authors showed increased plasma levels TNF-alpha and IL-6 in patients with chronic heart failure. After the treatment the plasma IL-6 levels decreased only in the patients III-IV NYHA functional classes, whereas the treatment had no effect on the plasma TNF-alpha levels.
Pol Merkur Lekarski 1999 Aug
PMID:[Do cytokines have any value in the patients with chronic blood circulation insufficiency?]. 1052 13

Free wall rupture of the heart is the most common cause of death following pump failure. The incidence of death is 10-16% of all deaths because of acute myocardial infarction (AMI). In respect of time between the onset of AMI to Cardiac Rupture (CR), early (80%) and late CR are distinguished. Other clinical classification distinguishes acute and subacute CR. CR is considered subacute if the time between the onset of typical symptoms of CR and irreversible shock is longer as 30 min. There are three problems to solve: 1) selection of patient particularly threatened with CR, 2) defining the prodroms of CR and early diagnosis, 3) advancing the methods of surgical treatment. CR occurs more often in women, hypertensive patients and patient > 60 years old sustaining the first infarction. Thrombolytic agents diminish overall mortality in AMI, but do not influence frequency of CR. There are three mechanisms of CR incidence: 1) blood effusion into the ischemic zone resulting in the loss of tissue strength, 2) influence of thrombolytic therapy on degradation and inhibition collagen synthesis, 3) absorption of collagen by lymphocyte infiltration in infarction zone. Cardiac insufficiency with cardiogenic shock and rapid increase of pericardial effusion in echo examination and electro-mechanical discordance are considered to be clinical signs of CR and tamponade. CRP is an independent marker of subacute CR. Surgical treatment is possible only in case of subacute CR. Pericardiocentesis and bloodletting could temporary diminish cardiac tamponade and allow transfer to the operating room.
Pol Merkur Lekarski 1999 Dec
PMID:[Cardiac rupture in acute myocardial infarction]. 1071 Sep 44

Obesity is a chronic complex disorder, which requires long-term treatment. The aim of this study was to estimate on the basis of current literature the coexistence of the cardiovascular system diseases and overweight. It was concluded that obesity is an independent risk factor for coronary heart disease, hypertension and heart failure.
Pol Merkur Lekarski 1999 Dec
PMID:[Obesity and cardiovascular diseases]. 1071 Sep 55

Heart rate variability (HRV) is a phenomenon to generation through the sinus node consecutive impulses in the different succession. HRV is regarded as a marker of autonomic nervous system tone of the heart. To assess HRV following methods: time domain, frequency domain and non-linear analysis are known. Time domain parameters correlate with frequency domain parameters. Some parameters can be used substitution, particularly reflect parasympathetic activity: rMSSD, pNN50 and HF. In clinical practice the most useful is time domain analysis based on 24-hours ecg Holter monitoring. Among time domain parameters the most significant prognostic value has SDNN. Decreased HRV following many diseases has been described. Significant prognostic value of decreased HRV after myocardial infarction (MI) and in patients with chronic heart failure (CHF) has been proved. Decreased HRV after MI is independent as well as ejection fraction (EF) sudden cardiac death risk factor. In patients with SDNN value below 50 ms high risk of cardiac death is observed. SDNN should be estimated on 7th day of MI to evaluate patients with high risk of sudden cardiac death. In patients after MI with ventricular tachycardia (VT) before VT decreased HRV is described. During MI beneficial influence of infarct-related artery patency on HRV is observed. HRV correlates with EF and infarct site too. HRV in patients with CHF correlates with EF and functional severity of CHF. Correlation between decreased HRV and increased mortality in CHF has been shown. In diabetic patients decreased HRV is observed. Following diabetes examination of HRV is useful to estimate early phase of autonomic neuropathy. Increase HRV parameters is observed in the course of beta-adrenolytic and converting enzyme inhibition treatment. In other diseases, including heart transplantation prognostic value of HRV and its clinical significance are still investigated.
Pol Merkur Lekarski 1999 Dec
PMID:[The assessment and clinical significance of heart rate variability]. 1071 Sep 56

Causes of death in children and adolescents treated with chronic peritoneal dialysis or hemodialysis in 1990-1999 in single centre were analysed. Overall 131 patients were treated, including 55 on peritoneal dialysis (PD) and 76 on hemodialysis (HD). Overall mortality in a 10-year period was 12% (16 patients). 10 patients in PD (18%) and 6 patients in HD group (7.8%) died. The main causes of death in PD patients were cardiac insufficiency, sudden cardiac arrest, ischemic stroke and atherothrombotic disease. In HD patients the main cause of death was hemorrhagic stroke.
Pol Merkur Lekarski 2000 Apr
PMID:[Analysis of causes of death in children and adolescents on chronic peritoneal dialysis and hemodialysis in 10 year period: single center experience]. 1089 53

The frequency of arrhythmias was determined pre- and postoperatively in adult patients with secundum atrial septal defect. The study group consisted of 224 pts who had undergone surgical repair of ASD II in between 1987-1993. The mean postoperative follow-up was 7.5 y. The group (160 F, 64 M, aged 17-66 y) was divided on 3 subgroups: I--age under 20 y--27 pts, II--20-40 y--131 pts, III--over 40 y--66 pts. We analysed pre- and postoperative parameters: 1) arrhythmias in the 24-h Holter recording, 2) pulmonary hypertension (PASP-Doppler), 3) coexisting diseases, 4) functional class of heart failure (NYHA). Most common abnormalities found were supraventricular tachyarrhythmias (22.8 pre- and 40.6% postoperatively). There was significant increase in frequency of arrhythmias after surgery in the subgroups II and III. Arrhythmias were most frequent in patients with coexisting arrhythmogenic diseases.
Pol Arch Med Wewn 1999 Dec
PMID:[Long-term follow-up of supraventricular tachyarrhythmia in adult patients with secundum atrial septal defect before and after surgery]. 1107 44

The aim of the study was to determine pre- and postoperative systolic pulmonary pressure in adult patients with ASD II. The study group consisted of 224 pts who had undergone surgical repair of ASD II in between 1987-1993. The mean postoperative follow-up was 7.5 y. The group (160 F, 66 M aged 17-66 years) was divided on 3 subgroups: age under 20 y--27 pts; 20-40 y--131 pts; and older then 40 y--66 pts. We analysed pre- and postoperative parameters: pulmonary hypertension (PASP-Doppler) and functional class (NYHA). Preoperative pulmonary pressure was 35-50 mm Hg in 69 pts (30.8%) of the group, and over 50 mm Hg in 29 (12.9%). In long-term follow-up of 98 (43.8%) operated patients with coexisting pulmonary hypertension, significant reduction of pulmonary pressure was observed in all patients, even in patients over 40 y. Functional class of heart failure NYXHA improved as well in all patients.
Pol Arch Med Wewn 1999 Dec
PMID:[Pulmonary hypertension in adult patients with secundum atrial septal defect before surgery and in long-term follow-up]. 1107 45

67 year old patient with chronic heart failure and persistent atrial fibrillation had overdosed glycosides for several months. The symptoms of gastrointestinal system and nervous system appeared after long term therapy with toxic doses of glycosides. Originally depression was diagnosed based on the central nervous system disturbances. Even though overdose of glycosides was diagnosed the blood serum glycoside level was within the therapeutic limits. Based on the precise analysis of the data, it was concluded that the reason for normal blood serum glycoside level in this case was coexisting hyperthyreosis.
Pol Merkur Lekarski 2000 Aug
PMID:[Digoxin as a cause of chromatopsia and depression in a patient with heart failure and hyperthyroidism]. 1108 26

The HIV-positive patient with dilated cardiomyopathy was described. Possible causes of heart failure in HIV infection was discussed. To achieve subclinical heart failure diagnosis authors suggest to perform echocardiography as a routine procedure in HIV-positive patients with low CD4 lymphocytes count and who have been infected for long time or when their disease becomes more advanced.
Pol Merkur Lekarski 2000 Aug
PMID:[Dilated cardiomyopathy in HIV infection]. 1108 27

In the most patients the mitral valve prolapse (MVP) syndrome has a good prognosis. The gradual progression of MR may cause the progressive LV dysfunction and development of heart failure. Long-term prognostic studies showed, that complications like endocarditis, cerebrovascular accidents occur frequently in pts. with mitral systolic murmur, thickened mitral valve leaflets and presence of MR. The diagnosis of MVP is made by cardiac auscultation and confirmed by echocardiography. The procedures usefulness in sudden death stratification are discussed. The management of the symptomatic patients, particularly the indication for prophylaxis of endocarditis and cerebrovascular accidents has been demonstrated. The indications for cardiac catheterisation and surgical treatment are presented.
Pol Merkur Lekarski 2000 Aug
PMID:[Mitral valve prolapse--diagnostic and therapeutic implications]. 1108 30


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