Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Echocardiographic study was performed in 31 uremic patients on maintenance hemodialysis (HD) with no apparent heart failure, valvular heart disease, pericardial effusion or coronary artery disease. On the basis of blood pressure patients were classified into two groups: 1) patients with normal arterial pressure (group I) (n = 19), 2) patients with blood hypertension (group II) (n = 12). Cardiac function was assessed immediately before and after HD session. Left ventricular end-diastolic diameter (EDD), left ventricular end-systolic diameter (ESD) and ejection fraction (EF) were calculated. Body weight, heart rate and mean blood pressure (mBP) were also measured. A significant decrease of EDD was noted in both groups during HD but it was less evident in group II (p < 0.05). ESD decreased significantly in group II (p < 0.01) when it did not change in group I. EF increased significantly only in group II (p < 0.05). Blood pressure decreased during HD in both groups. A significant inverse linear association between EF and ESD was noted during HD in both groups (r = -0.685; p < 0.001) but was more evident in group II. There was no association between and EDD (r = 0.199; NS). Similar analysis shows that ESD was significantly with mBP (group II--r = 0.914; p < 0.001, group I--r = 0.565; p < 0.05). Such association were not found for EDD and RR. Only in group II the decrease in mBP was statistical significantly correlated with the increase in EF. The decrease in EDD during HD exists probably due to changes in intravascular volume.(ABSTRACT TRUNCATED AT 250 WORDS)
Pol Tyg Lek
PMID:[The effect of blood pressure changes during hemodialysis on left ventricular systolic function]. 836 88

Rare case of hemolysis following an implantation of the biological mitral valve is presented. In 1985, biological mitral valve of Ionescu-Shiley type was implanted to a 45-year female patient for post-rheumatic mitral defect. Patient was in the III NYHA class before surgery. Her health status improved after operation. Several echocardiographic examinations have shown normal functioning of the implanted valve (normal gradient across the valve, no retrograde wave). Upper respiratory infection with subsequent progressive weakness, anemia, yellow skin, and heart failure occurred in 1991. Echocardiography has shown significant increase (twice) in the gradient across the valve (max 26, mean--14 mm Hg) and retrograde wave of the II degree as well as mitral insufficiency of the II degree. Laboratory tests have shown marked anemia with reticulosis, increase in blood bilirubin, increase in LDH activity (by about ten times), and a decrease in haptoglobins. Mitral valve dysfunction with hemolysis has been diagnosed. Patient was reoperated. Intraoperatively, incompletely healed valvular ring, and lesions to the leaves such as: fibrosis, thickening and partial deficits. Biological mitral valve was replaced with Corin-Carbotest artificial valve. Postoperative course was uncomplicated.
Pol Tyg Lek
PMID:[Hemolysis after bioprosthesis implantation in the mitral valve]. 836 96

We report two cases of pregnant women who developed an acute myocardial infarction. The proposed cause of massive myocardial anterior and interventricular wall infarction of the first patient appears to be bacterial intracoronary thrombus during the course of bacterial endocarditis. Acute insufficiency of the mitral valve caused by rupture chordae tendineae of the anterior mitral left was another complication. Labor contractions occurred on the 13th day of treatment. On the next day the patient gave birth to a healthy child by elective cesarean section. She was also qualified for an operation because of increased signs of left ventricular heart failure. Preoperative coronary angiography revealed occlusion of the anterior descending branch and reconstruction of its periphery. Other vessels were not changed. The patient was subjected to implantation of artificial valve, an aortocoronary by-pass and repair of atrial septal defect. Eighteen months follow up was uneventful. The second case was a 29 year-old pregnant woman who had previously undergone mitral commissurotomy admitted because of an acute myocardial infarction in the II trimester. No complication of the disease was observed.
Kardiol Pol 1993 May
PMID:[Myocardial infarction in pregnancy]. 836 44

Cardiac function was monitored by means of impedance cardiography in the early phase of chemotherapy in 30 patients with hematological malignancies. The patients were divided into two groups according to whether or not they revealed cardiac risk factors (age > 65, coronary heart disease, cardiac failure, hypertension, diabetes mellitus or prior mediastinal irradiation). It was found that the mean values of cardiac and stroke indices before chemotherapy were significantly lower in patients with cardiac risk factors. It was also noted that the mean values of these indices in both groups did not change significantly after anticancer treatment. However, in two patients a significant decrease of cardiac indices was observed. On the other hand, in several patients an increase of cardiac and stroke indices was recorded. It seems that careful measurements of cardiac function in cancer patients by impedance cardiography enable to analyze the influence of anticancer drugs upon the cardiovascular system. The results of these measurements may be used for the individualization of cancer therapy.
Acta Haematol Pol 1993
PMID:The importance of impedance cardiography in monitoring cardiac function in patients with hematological malignancies. 837 11

Captopril was administered to 50 carefully selected patients with severe circulatory failure (18 patients classified as class III and 32 as class IV according to NYHA) in daily dose of 37.5-75 mg for two years. Patients were also given digoxin, diuretic agents and iso-dinitrosorbide. Clinical improvement increased with duration of captopril therapy. A significant improvement following the correction of therapy was achieved in 15% of patients, following one month in 28%, three months--in 70%, and after 1 and 2 years in 84% of the treated patients. All patients survived for one year, and 44--for two years (88%). Clinical improvement was manifested by: diminished of dyspnoea, edema, pulmonary and liver congestion, increase in left ventricle ejection fraction, change of disease staging by one or two NYHA classes, and reduced ventricular rate during atrial fibrillation (in 30% of patients within one year). More noticeable improvement was seen in patients with baseline ejection fraction > 40% than those with EF < 30%, in hypertensive patients than normotensive, and in patients classified to III NYHA class. Ejection fraction increased from 37.9 +/- 9.2% before the treatment to 54.6 +/- 7.7% after a two-year captopril therapy (p < .01). Captopril greatly contributes to the successful therapy of the chronic severe heart failure.
Pol Tyg Lek
PMID:[Captopril treatment--2-year period of observation]. 841 45

A reciprocal constitutive 11;22 translocation is the most frequent, non Robertsonian translocation in man. We describe a case of partial trisomy 11q and 22q in a child with facial dysmorphy, hypotonia, heart failure, cryptorchism and psychomotor retardation. A marker chromosome was found in this child. Chromosome analysis with the fluorescence in situ hybridization, FISH technique showed that this marker chromosome was the product of 3:1 mejotic segregation of maternal (11;22) balanced translocation. Routine cytogenetic problems with identification of marker chromosomes can now successfully be solved with the FISH technique. The presented case clearly demonstrates the diagnostic usefulness of this newest method of cytogenetic analysis.
Pediatr Pol 1996 Mar
PMID:[Marker chromosomes as a product of familial translocation (11;22) identified with molecular cytogenetic methods]. 896 96

The aim of the investigation was microalbuminuria evaluation as an early symptom of renal involvement in systemic lupus erythematosus (SLE). Thirty patients aged 18 to 66 years (mean: 39,4 years) with mean duration of SLE of 6,3 years (range: 0,5 to 22 years) were examined. All of them fulfilled the preliminary criteria of the American Rheumatism Association for the classification of SLE. During the study none of patients had clinical or laboratory symptoms of nephropathy, hypertension, diabetes mellitus and heart failure. Microalbuminuria was measured by immunoturbidimetric method and the urine microalbumin concentration was expressed as the ratio microalbumin-creatinine concentration in 24 hour urine [equation: see text] Ratio I was 3,36 (+/- 2,76) in patients suffering from SLE comparing to I = 1,35 (+/- 0.89) in normal controls (p < 0.001). There was no correlation between increasing microalbuminuria and patients age and duration of disease. There was also no correlation between microalbuminuria and erythrocyte sedimentation rate or immunological activity parameters (i.e. antinuclear antibodies, anti dsDNA antibodies, levels of C3 and C4 components of complement).
Pol Arch Med Wewn 1996 Aug
PMID:[Microalbuminuria in patients with systemic lupus erythematosus]. 912

We present a current opinion about the management of chronic heart failure with beta-blocking agents. Pathophysiologic rationales for such treatment and clinical experience were analyzed. Most of the studies showed that long-term treatment of heart failure with beta-blockade produces improvement in symptoms, exercise tolerance, ejection fraction and central hemodynamics (CI, PCWP, MPAP, LVSWI, SVI). Treatment must be started at an extremely low dose and then must be increased gradually to therapeutic levels over several weeks. The titration phase must take place in the hospital. It was emphasized that the management of chronic heart failure with beta-blockers is not the routine management yet. Ongoing multicenters trials should finally determine the place of beta-blockers in the treatment of chronic heart failure.
Pol Merkur Lekarski 1996 Aug
PMID:[Beta-adrenergic receptor blockers in the treatment of chronic heart failure]. 915 10

During the first year after myocardial infarction 15-20% of patients die and about 50% because of sudden death. Appropriate therapy is essential to prevent arrhythmias and heart failure. Some pharmacological methods are discussed in main clinical aspects.
Pol Merkur Lekarski 1996 Aug
PMID:[Treatment of patients after myocardial infarction]. 915 13

CTEPH have not been widely recognised until recently. Introduction of the new, sophisticated, non-invasive diagnostic tools accounts for rapid progress in that field. Patients with high pulmonary hypertension have a very poor prognosis. Medical treatment (vasodilators, anticoagulants) does not change outcome. Pulmonary thromboendarterectomy is the only therapeutic option for the patients. It is essential to prevent further episodes of pulmonary embolism both over the long term and during the high risk perioperative period by means of inferior vena cava filters. In the Department of Medicine, Institute of Tuberculosis and Lung Diseases 18 LGM ivc filters have been inserted in patients with CTEPH since 1994. In 7 patients PTE was performed-in 5 cases good result was achieved, 2 patients died after surgery. In the latter group 5 patients died mainly because of severe heart failure. Only one non-fatal episode of pulmonary embolism was observed. It should be concluded that the LGM ivc filters are safe and effective in preventing episodes of pulmonary embolism in patients with CTEPH.
Pneumonol Alergol Pol 1996
PMID:[Implantation of LGM inferior vena cava filters in patients with chronic pulmonary hypertension during a course of major vessel thromboembolism--observation of 18 patients]. 918 83


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