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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The study revealed the usefulness of the apexcardiogram in the assessment of the contractile state of left ventricle in cases of ventricular extrasystolia. The pre-ejection period/left ventricular ejection time (PEP/LVET) ratio and isovolumic contraction period (IVCP) are good parameters for demonstrating the postextrasystolic potentiation, the lack of which occurs in severe heart failure. PEP/LVET and IVCP are R-R-interval dependent in parasystolia. In the establishment of the postextrasystolic potentiation, the authors contribute an important role to the ventricular filling during the compensatory pause.
Cor Vasa 1978
PMID:Significance of the apexcardiogram in non-invasive assessment of postextrasystolic potentiation. 8 17

M-mode echocardiography displayed abnormal echoes in the left atrium and posterior to the mitral leaflets in a child with severe heart failure. Cor triatriatum was demonstrated by angiography and cured by surgical excision. Subsequent echo studies no longer showed the abnormal structure.
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PMID:Echocardiographic diagnosis of cor triatriatum. 28 59

Apexcardiographic examinations were carried out of 86 hypertensive patients without clinically manifest heart failure. The amplitude of the wave a (or the per cent fraction of the wave a of the total amplitude) and the maximal rate of wave rise, df/dta were statistically significantly higher in the hypertensive patients than in normal subjects. The findings are interpreted as a manifestation of an increased left ventricular rigidity and of an increased atrial contractility in hypertensive patients. No correlation was found between the apexcardiographic indicators checked and the indicators of the cardiac pump function. In 46 hypertensive patients, in addition, a dynamic exercise test was performed (50 W for 6 min); 1 minute after cessation of exercise an apexcardiogram was recorded. An increase in the a/T quotient (greater than or equal to 5%) was found in 20; a decrease (=5%), in 10; and no change (less than +/- 5%), in 16 hypertensive patients. The postexercise apexcardiographic changes had no correlations with haemodynamic changes occurring during exercise.
Cor Vasa 1979
PMID:[A-wave in calibrated apex cardiogram in hypertension. Studies during rest and after exertion]. 51 99

A phonocardiological analysis of the first heart sound was made and systolic time intervals were measured in 40 patients (ischaemic heart disease, hypertensive heart disease, cardiomyopathies) with incipient cardiac failure (functional groups I--II according to the NYHA) with auscultatory changes of the first heart sound and in controls of randomly selected healthy persons or patients in whom cardiopulmonary disease was excluded. The patients in all diagnostic groups differed significantly (P less than 0.05--0.001) in practically all the phonocardiographic indicators from the controls. The most constant abnormal finding was a pathological split of the first heart sound which may be divided into three phonocardiographic forms. Simultaneously, systolic time intervals alterations (P less than 0.02--0.001) were also found in these patients and indicated a lowered performance of the left ventricle. The results suggest that 1) a certain relation exists between systolic time intervals and the phonocardiographic pattern of the first heart sound in patients with cardiovascular diseases and those without it; 2) the modified (pathologically splitted and prolonged) first heart sound could be a sign of incipient cardiac failure.
Cor Vasa 1979
PMID:The first heart sound abnormalities accompanied with alteration of systolic time intervals in incipient heart failure. 53 4

The myocardial infarct size was assessed on the basis of serial analyses of serum creatine phosphokinase (CPK) in 70 patients with first transmural myocardial infarction. Clinical symptoms of heart failure (Killip II-III) were found in patients with infarcts larger than 50 CPK-g-equ; in patients with lung oedema the infarct size averaged 104.2 CPK-g-equ. Patients without clinical and roentgenological evidence of left heart failure (Killip I) had infarct sizes always lesser than 50 CPK-g-equ, averaging 31.7 CPK-g-equ. Precordial mapping of the QRS complex in patients with anterior wall infarction revealed a significant correlation (r = 0.916) between the sum of voltages of Q waves on a 30-lead map recorded 24 hours after hospitalization and the enzymically assessed infarct size. Exact skiagraphic and auscultatory examinations of the heart and lungs, together with precordial mapping of the QRS complex, in patients with anterior wall infarct allow a relatively accurate quantification of the infarct size for prognostic classification of the patients.
Cor Vasa 1979
PMID:Assessment of myocardial infarct size in clinical practice. 54 93

The presence of an abnormal P terminal force of the P wave in lead V1 (PTFV1) was demonstrated on the initial electrocardiograms in 69 of the 200 patients with transmural acute myocardial infarction. 61.5% of the total cases with a lethal outcome during hospitalization belonged to this group. The mortality of the patients who presented this ECG sign of left atrial hypertension at the onset was 53.7%, thus differing significantly from that in patients without the sign (22.1%). The PTFV1 anomaly has a prognostic value in patients without complications as well as in those with heart failure at the onset of the disease. The appearance during hospitalization of major arrhythmias and disturbances of conduction and of sudden death is significantly correlated to the presence of abnormal PTFV1 on the admission electrocardiograms.
Cor Vasa 1977
PMID:Prognostic value of an abnormal P terminal force in lead V1 at onset of acute myocardial infarction. 59 2

Apexcardiograms [ACG] recorded in 64 patients with anterior acute myocardial infarction disclosed in 36 cases [56.2%] paradoxal systolic precordial pulsation considered as an expression of ventricular dyskinesis [VD]. The functional significance of VD was assessed by the left ventricle systolic time intervals. There was a significant shortening of the left ventricular ejection time (LVET) and a significant increase in the pre-ejection period (PEP) and of PEP/LVET ratio in patients with VD. The heart/chest ratio was greater in patients with VD but the difference was not statistically significant. The condition of the heart after the acute phase of myocardial infarction was much better in patients without VD or with transient VD in than in those with permanent VD. 91.3% of the patients with permanent VD presented heart failure and belonged to the functional class III-IV. These findings indicate that patients presenting ACG-assessed VD have frequently an altered cardiac performance and a worse long-term prognosis.
Cor Vasa 1977
PMID:Clinical significance of ventricular dyskinesis in acute myocardial infarction assessed by apexcardiography. 61 Sep 91

In 21 patients with ischaemic heart disease, the values of the anginal threshold were investigated during cardiac pacing and an exercise test. It was found that in the pacing test, ischemia could be expected to appear at a heart rate by 30% faster than that in ischaemia induced by exercise. If ischaemia was successfully induced in both tests, the threshold values of the time-tension indexes were equal, whereas the value of the pressure-time per minute index was 20% higher in exercise-induced ischaemia. In patients with hypokinetic circulation, during pacing the pressure-time per minute index first increased and then paradoxically decreased; this reaction can help find out patients with haemodynamic signs of heart failure.
Cor Vasa 1977
PMID:A comparison between cardiac pacing and exercise tests in patients with angina pectoris. 61 Sep 93

The incidence, circumstances, and mechanism of development of cardiac arrest in 786 patients with myocardial infarction treated at a coronary care unit within a five-year period were studied and clinical factors are analysed with respect to success of resuscitation. One or more episodes of cardiac arrest occurred in a total of 156 patients (19.8%). Of these, 25 (16.0%) were successfully resuscitated and 131 (84.0%) died. At the clinical ward where the patients had been transferred after the acute stage, cardiac arrest occurred in additional 22 patients, of whom two were successfully resuscitated. Thus, the total number of successfully resuscitated patients throughout the five-year period was twenty-seven. The results of resuscitation were poorer in elderly patients, in those with anterior infarction, and above all in patients with severe symptoms of mechanical heart failure. Anamnestic factors (chronic angina pectoris, previous myocardial infarction, hypertension, diabetes mellitus, ischaemic disease of the lower limbs) were not significantly associated with the results of resuscitation. Primary ventricular fibrillation was the principal mechanism of cardiac arrest in 24 of the 27 patients successfully resuscitated, and its total incidence in the investigated group was 3%. The prognosis of resuscitation in patients with primary ventricular fibrillation was very good, and in all of them the resuscitation was successful and permanent.
Cor Vasa 1978
PMID:Incidence of circulatory arrest in patients with acute myocardial infarction in coronary unit. Mechanism of their genesis and factors conditioning successful resuscitation. 67 95

Animal experiments have proved that the earliest morphological manifestations of acute lesions of myocardial cells (at the optical microscopic level) are myofibrillar changes detectable by polarized-light microscopy. As basic types of myocardial cell lesions there can be distinguished segmental and subsegmental contractures, intracellular myocytolysis, and primary granular disintegration. These changes persist in animal myocardium for many hours and thus can be recognized at autopsy. The application of polarized-light microscopy makes possible a diagnosis of early stages of myocardial infarction, associated with lesions of myocardial cells appearing at the periphery of the ischaemic zone already within the first minutes, revelation of focal metabolic changes leading to acute heart failure, and diagnosis of ventricular fibrillation, characterized by subsegmental contractures of the subepicardial and subendocardial layers of the myocardium.
Cor Vasa 1977
PMID:Use of polarized-light microscopy in histological diagnostics of early stages of ischaemic and metabolic myocardial lesions. 87 97


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