Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 42-year-old patient with acute left-ventricular failure is described in whom pheochromocytoma was diagnosed only after prolonged and fruitless efforts. Pheochromocytoma may present without the typical features of paroxysmal or sustained hypertension, headache, increased sweating, and palpitations. Therefore, in cases of acute left-sided cardiac failure of primarily undetermined origin, pheochromocytoma should be considered in differential diagnosis.
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PMID:[Acute left heart insufficiency: possible leading symptom of a pheochromocytoma]. 157 67

A 42-year-old man was admitted because of huge retrovesical mass. The organ from which the tumor originated was unknown. The biopsy specimen showed poorly differentiated adenocarcinoma. The tumor increased rapidly and could not be resected because of peritoneal dissemination. The mass fully occupied the abdominal space with marked dyspnea. Fortunately, a marked decrease in the tumor size was noted by neo-MFC without any side effect. Therefore, the patient could enjoy a daily life until he died suddenly of cardiac failure 8 months after first admission. Retrovesical tumor is usually discovered at advanced stage because of lack of symptoms. For recovery of good performance status combined chemotherapy with relatively mild side effect must be selected and administered for a long time.
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PMID:[A case report of retrovesical tumor effectively responsive to chemotherapy]. 250 51

A 42 year old man without history of rheumatic heart disease was admitted to the hospital with severe aortic insufficiency and heart failure. There were no clinical data of an infectious disease. The bidimensional echocardiogram showed vegetations involving the aortic valve leaflets. With the diagnosis of acute aortic insufficiency caused by infective endocarditis the patient was submitted to surgery. During surgery the existence of endocarditis secondary to a mycotic agent was demonstrated. The fungus was latter identified as aspergillus fumigatus. The postoperative course was uneventful. The good results obtained in this case confirm recent reports advising an urgent surgical approach of cases of infective endocarditis secondary to mycotic agents, and support the view that echocardiography may be a valuable tool in the diagnosis of this entity.
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PMID:[Aspergillus endocarditis. Report of a case treated surgically with success]. 703 62

A 42-year-old man presented with acute myocardial infarction. The ECG on admission to hospital showed "Q wave" inferior myocardial infarction and "non-Q wave" anterior infarction. Subsequently, he was readmitted to hospital on many different occasions for cardiac failure. About 15 months after the patient was first seen, two-dimensional echocardiogram (2D echo) showed dilatation of all 4 cardiac chambers and severe global hypokinesia of the left ventricle. In addition, a large echo dense mass was seen at the apex of the left ventricle and 2 smaller echo dense masses were present at the right ventricular apex. The echocardiographic characteristics of these 3 masses strongly suggest that they represent mural thrombi. Two-dimensional echocardiographic detection of biventricular thrombi has rarely been described in the past. This case together with the previously reported case by Friedman and Buda suggest that 2D echo may be a valuable test for the diagnosis of biventricular thrombi.
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PMID:Two-dimensional echocardiographic detection of biventricular thrombi. 757 Jan 24

A 42 year old man admitted with effusive-constrictive pericarditis had diastolic dysfunction and pericardial thickening. Pericardiectomy was performed because of uncontrolled heart failure. The Epstein-Barr viral IgG antibody titre was exceptionally high. The EB viral genome was demonstrated in the resected pericardium by polymerase chain reaction and in situ hybridisation. EB viral pericarditis was diagnosed.
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PMID:Demonstration of the Epstein-Barr genome by the polymerase chain reaction and in situ hybridisation in a patient with viral pericarditis. 839 86

A 42-year-old insulin-dependent diabetic man presented with severe bilateral gustatory sweating associated with a deterioration in his glycaemic control. Conventional oral antimuscarinic medication was contraindicated because of his cardiac insufficiency. Topical 0.5% glycopyrrolate cream was tried and applied on alternate days to his face, which resulted in the complete cessation of his gustatory sweating without side-effects. Topical glycopyrrolate cream is an effective treatment of diabetic gustatory sweating without the adverse effects commonly found with oral anti-muscarinic medication.
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PMID:Treatment of diabetic gustatory sweating with topical glycopyrrolate cream. 873 34

A 42-year-old man presented with cough, chest pain and dyspnea. The chest roentgenogram revealed a large mass shadow in the right upper and middle lobes with atelectasis and pleural effusion. Massive polypoid tumor extending into the left atrium was diagnosed by computed tomography and two dimensional echocardiography. In order to prevent sudden death and cardiac failure, surgery was performed. At first, the polypoid tumor in the left atrium was removed with a partial resection of the left atrial wall under cardiac arrest using cardiopulmonary bypass. Then, a right pneumonectomy was performed. Episodes of embolism were not observed during surgery. His postoperative course was almost favorable. The size of the tumor in the right lung was 18 x 15 x 8 cm and the one in the left atrium was 6.5 x 4.5 x 3 cm, respectively. Pathological examination of the resected specimen revealed the evidences of large cell carcinoma extending into the left atrium. Local recurrence with S9 metastasis of the left lung were detected 6 months after surgery, and he died 6 months later. It is emphasized that the extended surgery using cardiopulmonary bypass was useful for both prevention of embolism and improvement of quality of life.
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PMID:[A successful removal of T4 lung cancer with its left atrial extension using cardiopulmonary bypass]. 902 67

Blood cysts of the heart valves are commonly reported at postmortem examination of infants but are rare seen in older children and adults. A 42-year-old woman was referred to our hospital for cardiac evaluation because of dyspnea on exertion and heart murmur. There was no history of cyanosis or cardiac failure. Cardiac catheterization revealed valvular pulmonary stenosis and atrial septal defect. Right ventricular angiography showed the circular filling defect 0.7 x 0.7 cm in size at the suprapulmonary valve. However, this preoperative abnormal finding was diagnosed as a blood cyst after surgery. At operation a blood cyst originating from the right cusp of the pulmonary valve was found and resected, and was followed by commissurotomy of the pulmonary valve and direct closure of the atrial septal defect. Her postoperative course was uneventful.
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PMID:[Blood cyst of the pulmonary valve in an adult--a case report]. 917 Aug 73

Patients in the chronic phase of Chagas' disease suffer from a slowly evolving inflammatory cardiomyopathy that can lead to severe cardiac dilatation, congestive heart failure, and death. This process appears to be caused by autoimmune recognition of heart tissue by a mononuclear cell infiltrate decades after infection with the parasite Trypanosoma cruzi. Recent evidence suggests that there are circulating antibodies in chronic chagasic patients that alter the physiological behavior of the heart on binding to G-protein-coupled cardiovascular receptors, including beta1-adrenergic and m2 muscarinic receptors. A 42 kDa fusion protein was constructed that contains the central part of the third intracellular loop (i3; Arg(267)-Arg(381)) of the human m2 muscarinic receptor, linked to glutathione S-transferase. This fusion protein was overexpressed in Escherichia coli and subsequently purified by affinity chromatography. Based on Western blots, the i3 loop is specifically recognized by the sera of chronic chagasic patients who have reached advanced stages of cardiac failure (according to the Los Andes classification). Analysis of the prevalence and distribution of these antibodies shows a strong association between seropositive patients and moderate (group II) to severe (group III) heart dysfunction.
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PMID:Presence of antibodies against the third intracellular loop of the m2 muscarinic receptor in the sera of chronic chagasic patients. 1054 84

A 42 year old woman presented with an auricular tachyarrhythmia as well as a congestive cardiac failure ascribed to a viral myocarditis, two months after an adenectomy for primary hyperparathyroidism. Serum calcium was low whereas parathormone serum was increased suggesting a "hungry bone syndrome". The left ventricular dysfunction persisted for a long period even after normalization of the serum calcium. The contributory role of hypocalcemia in unexplained or refractory heart failure is reviewed. The eventuality of a cascade effect is evoked.
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PMID:[Cardiac decompensation after an adenectomy for primary hyperparathyroidism: hypocalcemic cardiopathy or cascade effect?]. 1096 43


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