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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In patients with postinfarction cardiosclerosis, change in central haemodynamics appeared to be associated with the degree of cardiac insufficiency and is clearly related to the size of damage to the myocardium.
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PMID:[The central hemodynamic characteristics of patients with postinfarct cardiosclerosis and heart failure]. 1042 93

Endocardiac hemodynamics was studied in 81 patients with postinfarction cardiosclerosis with intact and decreased ejection fraction (EF > 57% and EF < 57% respectively) using echocardiographic B- and M-mode techniques. Patients with postinfarction cardiosclerosis without overt heart failure demonstrated a decline in the left ventricular pump function which was more manifest in postinfarction cardiosclerosis presenting with a decreased ejection fraction. A decline in the pump function of the myocardium in those patients having postinfarction cardiosclerosis without overt cardiac insufficiency is an indication for prescription of those medicinal substances enhancing the inotropic function of the myocardium (cardiac glycosides, peripheral vasodilators).
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PMID:[The indices of intracardiac hemodynamics in patients with postinfarct cardiosclerosis]. 1082 72

Hemodynamic parameters were measured before and 30 min, 1, 2 and 3 hours after intake of 12.5 mg capoten in acute pharmacological test at 7.00, 10.00, 13.00, 16.00, 19.00 and 22.00 in 70 patients with ischemic heart disease, postinfarction cardiosclerosis with heart failure stage I-II. The patients were randomized into 6 groups according to the time of the pharmacological test. As shown by tetrapolar chest rheography, the lowest peripheral vascular resistance and the highest cardiac ejection occurred if capoten was used at 10.00. In contrast, vascular resistance rose and cardiac ejection fell in capoten intake at 13.00. At the other hours circulation responded more favourably than at 13.00 but not so strongly as at 10.00. Different hemodynamic reaction to capoten within 24 hours demands further studies.
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PMID:[Chrono-pharmacodynamics of capoten in patients with ischemic heart disease, postinfarction cardiosclerosis with cardiac failure]. 1184 Aug 8

Results are submitted of clinical, instrumental, and laboratory methods of investigation in 50 patients with postinfarction cardiosclerosis before the start of the treatment and four weeks after conventional cardioactive therapy (control group) and the analogous therapy involving the use of a new biologically active home-produced drug preparation biotroph-3 in a complex therapy of patients with postinfarction cardiosclerosis permits shortening time for the general clinical improvement of the patients' state to be achieved due to apparent antiarrhythmic, antiischemic, and hypotensive effects along with reduction of manifestations of heart failure, as evidenced by the analysis of the results obtained.
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PMID:[Use of biotrof-3 in complex treatment of patients with postinfarct cardiosclerosis]. 1214 76

78 patients with postmyocardial infarction cardiosclerosis and moderate chronic cardiac failure (NYHA functional class 0-2) were given standard medication (enalapril, aspirin, atenolol) and took underwater massage douche. The effects of the latter on diastolic dysfunction of the left ventricular myocardium were studied. The above hydrotherapy changed parameters of left ventricular diastolic filling in 64% of the examinees: in 40% these parameters improved, in 23%--deteriorated. Clinical and device criteria essential for hydrotherapy outcomes are described.
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PMID:[Effects of underwater massage douche on left ventricular diastolic function in patients with chronic cardiac failure and postinfarction cardiosclerosis]. 1238 May 23

Hemodynamics and ventricular remodeling were studied echocardiographically in 192 men with heart failure (NYHA functional class I), arterial hypertension (AH) of stage I-III and clinical picture of ischemic heart disease (IHD). The latter presented in the patients with stable angina pectoris of FC I-II (SAP), unstable angina pectoris (UAP) without foci, paroxysmal atrial fibrillation, acute myocardial infarction (MI), postinfarction cardiosclerosis (PC) with SAP or UAP. The control group consisted of 41 healthy men. The patients had AH stage 1. The patients and healthy controls differed significantly by the size of the aorta, left atrium, thickness of the interventricular septum and posterior wall of the left ventricle. There was a significant left-ventucular hypertrophy in the groups with patients with MI, SAP and PC, UAP and PC (p < 0.001). In these groups the type of left ventricular remodeling was characterized as excentric type of left ventricular hypertrophy without its delatation. Normal left ventricular geometry was in healthy men, SAP, UAP, paroxysmal actual fibrillation.
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PMID:[Remodeling in cardiac failure of functional class I due to arterial hypertension associated with ischemic heart disease]. 1511 70

Based on a 10-year prospective follow-up a study was made into survival in 68 patients with chronic cardiac insufficiency (CCI) having developed as a result of hypertensive disease and postinfarction cardiosclerosis. Also studied in the above series were risk factors for death. It has been found out that life span in CCI is, in the mean, seven years while risk for death beyond 10 years increases six-fold. The identified prognostic factors included etiology of CCI, age of patients, end-systolic volume of the left ventricle, and a week dosage of furosemide. It was etiology of CCI that proved to be the most significant risk factor. In some patients with postinfarction cardiosclerosis and CCI average life span comes up to more than five years, with risk for death being significantly higher than in CCI patients with CCI having developed in the wake of hypertensive disease over the whole of the period of study.
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PMID:[Survival and risk factors in patients with chronic cardiac insufficiency (results of a long-term prospective observation)]. 1531 97

The study was undertaken to examine the specific features of autonomic regulation and the parameters of central hemodynamics in patients with postinfarct cardiosclerosis (PICS) and circulatory insufficiency who had different types of left ventricular remodelling (LVR). Thirty-two patients with PICS and heart failure (HF) were examined. The autonomic status was studied, by analyzing cardiac rhythm variability (CRV) from 5-min resting cardiointervalograms and by the cardiovascular tests described by D. Y. Ewing; integral rheography was also performed. The patients were divided into 2 groups according to the type of LVR. Patients with PICS + HF and concentric LVR were found to have a more balanced autonomic circulatory regulation and a hemodynamic type that was more energetically efficient for the myocardium. Those with PICS + HF and eccentric LVR had a hemodynamic type that was less efficient for the myocardium, which was accompanied by the enhanced activity of the sympathetic nervous system (SNS) even at resting. Patients with PICS + HF, particularly in the presence of the latter's higher functional class and eccentric LVR, seemed to have desensitized adrenoceptors and impaired baroreflex activity, as appeared as no rise in peripheral vascular resistance with the enhanced sympathetic activity. The findings support the expediency of using beta-adrenoblockers in HF in patients with PICS, particularly with eccentric LVR. Analysis of cardiac rhythm variability is sufficiently informative in evaluating autonomic regulation and autonomic balance, SNS tone in particular, in patients with HF.
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PMID:[Automatic regulation and central hemodynamics in patients with postinfarct cardiosclerosis and heart failure]. 1544 69

According to the intensity and duration of invasion, superinvasion opisthorchiasis in laboratory animals and human beings involves all cardiac layers; the myocardium is mostly damaged. In its early phase, vascular inflammation of the microcirculatory bed, dystrophy, necrosis of striated muscle fibers progressing to diffuse cardiosclerosis result from abnormal immunological processes; due to reflex exposures (Botkin's syndrome), there may be persistent cardialgias that may progress to the clinical manifestations of chronic ischemic heart disease. Unpredictable dissipative clusters of metabolic Opistorchis may predispose to different forms of myocarditis progressing to focal and diffuse cardiosclerosis. In these cases, the death of patients with superinvasion opisthorchiasis results from acute or chronic heart failure. Dehelmintization in these patients fails to eliminate myocardial changes (cardiosclerosis) that further determine the clinical presentation of cardiac pathology.
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PMID:[Cardiac syndrome in opisthorchiasis]. 1548 76

The specific features of synthesis of inducible heat shock proteins with a molecular mass of 72 kDa (HSP72i) with peripheral lymphocytes were studied in patients with postinfarct cardiosclerosis and signs of chronic heart failure (CHF). According to the baseline level and time course of changes in lymphocytic accumulation of HSP72i during treatment, the patients with CHF were divided into 3 groups. Great differences were found in the course of CHF in patients with different levels of HSP72i synthesis. There were significant relationships between the content of HSP72i and the basic clinical, laboratory, and instrumental characteristics of CHF. The baseline level of HSP72i and the time course of changes in its accumulation by peripheral lymphocytes in patients with CHF were shown to be of prognostic value.
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PMID:[The specific features of synthesis of heat shock proteins in patients with postinfarct cardiosclerosis]. 1554 Apr 17


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