Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors describe a case of 44-year-old woman with severe cardiac failure due to chronic hypocalcemia caused by primary hypoparathyroidism with coexisting Fahr's disease. This type of cardiomyopathy was refractory to conventional therapy. Spectacular clinical improvement and normalisation of echocardiographic left ventricular parameters were observed following supplementation with calcium and alphacalcidol. The effects of calcium ions and parathyroid hormone on myocardial contractility, ECG changes and serum CK activity are discussed.
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PMID:[Hypocalcemic cardiomyopathy--a reversible type of cardiac failure in a patient with primary hypoparathyroidism and coexisting Fahr's disease]. 1450 39

In our report we would like to present a case of a 60-year-old patient with epileptic seizures, affective disturbances, only mild neurocognitive disorders and cardiomyopathy. A female patient was taken to the internal ward with a tentative diagnosis of recurrent syncope. Laboratory results disclosed severe hypocalcaemia, hypoparathyroidism, and hypothyroidism. An echocardiogram revealed left ventricle systolic dysfunction. Computed tomography revealed massive intracranial calcifications typical for Fahr's syndrome. Our patient demonstrated only mild neurological and psychiatric symptoms, but developed hypocalcaemic heart failure. It is possible that some cases of Fahr's syndrome remain undiscovered, particularly patients taken to internal wards with mild neurological or psychiatric signs.
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PMID:Recurrent syncope and hypocalcaemic cardiomyopathy as manifestations of Fahr's syndrome. 2237 31