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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a 63-year-old woman with longstanding type I diabetes mellitus, CAD and chronic heart failure, a subacute myocardial infarction developed, together with decompensation of cardiac function and diabetes and concurrent pneumonia. Acute heart failure with acute renal failure on top of diabetic nephropathy, and interstitial pulmonary edema was initially treated with hemofiltration and catechol amines together with antibiotic and perfusor-regulated insulin therapy, and systemic heparinization. Subsequent chronic treatment with digitalis, acetyl salicylic acid, insulin and a combination of an ACE inhibitor and a loop diuretic resulted in an improvement of heart failure to NYHA functional class II where PTCA of coronary multi-vessel disease could be performed with low risk.
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PMID:[Heart failure after myocardial infarct in decompensated diabetes mellitus. Acute therapy with catecholamines--long-term therapy with ACE inhibitor-loop diuretic combination]. 937 33

Acute heart failure in adults is the unfolding of heart failure in minutes, hours or a few days. Low output heart failure describes a form of heart failure in which the heart pumps blood at a rate at rest or with exertion that is below the physiological range and the metabolizing tissues extract their required oxygen from blood at a lower rate, causing a proportionately smaller oxygen amount remaining in the blood. Therefore, a widened arterial-venous oxygen difference occurs. High output heart failure is characterized by pumping blood with a rate above the physiological range at rest or during exertion, resulting in an arterial-venous oxygen difference, which is normal or low. This may be caused by peripheral vasodilatation during sepsis or thyrotoxicosis, blood shunting, or reduced blood oxygen content/viscosity (Fig. 1). The differentiation between low output heart failure versus high output heart failure is of highest importance for the choice of therapy and therefore the information and the monitoring of the systemic vascular resistance. Patients who present with acute heart failure suffer from a severe complication of different cardiac disorders. Most often they have an acute injury that affects their myocardial performance (eg, myocardial infarction) or valvular/chamber integrity (mitral regurgitation, ventricular septal rupture), which leads to an acute rise in left-ventricular filling pressures resulting in pulmonary edema.
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PMID:New strategies for the management of acute decompensated heart failure. 1135 11

Acute heart failure is unusual in the pediatric population, but in many situations it justifies aggressive therapy. For example, children with lymphocytic myocarditis have an overall survival rate of nearly 90%, with complete myocardial recovery for the majority. Pharmacologic agents traditionally have been the mainstay of medical therapy for acute heart failure, but, in recent years, there has been increasing interest in using measures that reduce the myocardial workload. This article highlights nonpharmacologic approaches to the management of severe heart failure in the critically ill child. It also concentrates on physiologic approaches that address the balance between oxygen demand and delivery; the manipulation of cardiopulmonary interactions to optimize ventricular function; and the use of mechanical circulatory support as a method of achieving ultimate myocardial rest.
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PMID:Nonpharmacologic treatment of acute heart failure. 1138 58

A role of the potent and long-acting vasoconstrictor peptide endothelin (ET)- I in the pathophysiology of chronic human heart failure has been postulated, based upon indirect evidence such as elevated plasma ET-1 levels and their relationship to the degree of haemodynamic impairment. Acute heart failure shares many features of chronic heart failure, albeit in an exaggerated fashion. As both the mixed ETA/ETB-receptor antagonist bosentan and the selective ETA receptor antagonist BQ 123 acutely improved the haemodynamics of chronic heart failure patients, there seems to be good reason to believe that ET-1 receptor antagonism may also be of benefit in the setting of acute heart failure. However, appropriate trials will have to be performed to document the clinical benefit of such an approach. Finally, the question remains open as to whether mixed ET-1 receptor antagonists like bosentan will prove better, worse or equal to antagonists that block the ETA, receptor only.
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PMID:Rationale and perspective of endothelin-1 antagonism in acute heart failure. 1181 79

A case of acute poisoning with amlodipine with deep hypotension, transient oliguria and clinical signs of acute heart failure was described. A woman of 23 years swallowed intentionally 60 tablets of amlodipine (600 mg). After eleven hours of ingestion she was admitted to Warsaw Poison Control Centre. She was in severe clinical condition; tachycardia and deep hypotension were the prominent signs of poisoning. There was not CNS depression. Intensive treatment with i.v. catecholamines (dopamine, norepinephrine), crystalloids (with continuous control of central venous pressure), and i.v. calcium salts (with control of plasma calcium concentration) was started immediately. The patient did not improve but got worse. Acute heart failure developed, especially of left ventricle, so i.v. crystalloids were stopped and dubutamin, morphine, nitroglycerin and glucagon were introduced. Because of oliguria and insufficient effect of high doses of furosemide four-hours hemodiafiltration was set in. The patient's condition slowly improve after third and forth day of hospitalization. The systolic blood pressure rose, heart work was really better and on sixth day--the stabilization of diastolic blood pressure was definitely achieved. The patient was discharge in good condition with heart ejection fraction of 65% measured echocardiographically.
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PMID:[Deep hypotension with transient oliguria and severe heart failure in course of acute intentional poisoning with amlodipine]. 1186 80

Acute heart failure may be defined as the failure of the circulation to supply the demands of metabolising tissues due to acute cardiac dysfunction. First aid measures aimed at reducing symptomatology should be chosen with respect to their ability to improve cardiac function. The use of diuretics in acute heart failure does not sit well with the principle of improving cardiac function whereas the use of vasodilators does. As with any circulatory disturbance treatment must be guided by appropriate monitoring and the demands of metabolizing tissues must be reduced. Inotropes should be reserved for severe cases where other treatments have failed. This is to avoid the increased myocardial oxygen demand as a result of inotrope use.
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PMID:Management of acute heart failure. 1202 82

Acute heart failure is a life-threatening medical emergency, most commonly occurring as an immediate or delayed complication of acute myocardial infarction (AMI), or resulting from severe hypertension or valvular defects (stenosis or incompetence). Occasionally it is caused by patients' non-compliance with medication orders. In this case the patient had a history of three previous AMIs, controlled hypertension, and controlled congestive heart failure (CHF) for which he took two 40 mg frusemide tablets (a very potent oral diuretic) each morning. Because he had experienced bladder discomfort during the latter stages of previous appointments he decided to delay taking the diuretic until after his appointment and acute heart failure ensued.
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PMID:A case report of acute heart failure caused by a patient delaying taking his diuretic medication. 1203 61

Acute heart failure is a life-threatening medical emergency and appropriate management can reduce the morbidity and mortality of heart failure. Despite advances in treatments, the number of deaths has increased steadily. Therefore, the guideline was assigned to convey to the physicians the virtue of medical management with recent trends in pharmacological and nonpharmacological treatments. Japanese new guidelines for the management of acute heart failure have been published from the Japanese Circulation Society in October, 2000, which was partially based on ACC/AHA guideline in 1995 but prepared under consideration of medical benefits system and health care system in Japan. We expect that the guideline would be revised to make it more useful with continual advances in the management strategies in the future.
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PMID:[Acute heart failure]. 1275 93

Acute heart failure is always an indication for referral to an intensive care unit. In the widest sense, the term acute heart failure includes the manifestation forms of pulmonary edema, cardiogenic shock or rapid-onset decompensated cardiac insufficiency unaccompanied by shock or pulmonary edema (low-output syndrome). Acute heart failure may occur in the absence of previously known heart disease. Existing prior specific diseases that may end in acute cardiac insufficiency include acute myocardial infarction, decompensated cardiomyopathy, myocarditis, cardiac tamponade, endocarditis or arrhythmogenic heart failure.
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PMID:[Acute heart failure]. 1537 19

Acute heart failure is a rapidly growing clinical problem in the United States. There are few randomized clinical trials to guide treatment; however, important observational data are now emerging from the Acute Decompensated Heart Failure National Registry regarding the demographics and treatment of these patients. Management consists largely of identification and treatment of precipitating factors, correction of comorbid conditions, and IV diuretics and vasodilators. Nitroprusside is a valuable treatment, but its use is usually restricted to patients in the intensive care unit who are undergoing hemodynamic monitoring. Nesiritide is being increasingly employed. Specialized strategies such as dialysis, continuous venous-venous hemodialysis, extra-corporeal membrane oxygenator, left ventricular assist device, and heart transplantation are employed in a small subset of patients. Although recovery is the rule, the in-hospital mortality for acute heart failure is high and the readmission rate is very high. Prevention of acute heart failure by avoiding factors known to precipitate decompensation remains the most cost-effective strategy.
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PMID:Acute heart failure: patient management of a growing epidemic. 1553 70


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