Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

False aneurysms of the left ventricle were repaired in four patients (average age, 61 years). The etiology was myocardial infarction in three patients and disruption of an apical left ventricular cannulation site in the fourth. The interval from initiating event to surgery averaged 11 months. One patient was in cardiogenic shock and succumbed in the operating room from myocardial failure. The other three patients, in functional class III at the time of surgery, survived and are currently asymptomatic. The literature records 43 patients who have undergone surgical repair of a false aneurysm of the left ventricle. The causes were myocardial infarction (12 patients), operative injury (13 patients), penetrating trauma (11 patients), and blunt trauma (seven patients). Twenty-seven (63%) were under the age of 50 years. In those who were limited by symptoms, congestive heart failure predominated. Forty seven per cent of the patients were operated upon in the first five months following the initiating event; 61% within the first year. Only four patients underwent surgery more than 48 months after the myocardial insult. Thrombus was present in 28% of the aneurysms. Morbidity was recorded in nine patients, and six patients (14%) died. This study documents the necessity for early surgical repair and the relatively low operative mortality obtained with this lethal lesion.
 ...
PMID:False aneurysm of the left ventricle. Report of four cases and review of surgical management. 44 96

The clinical and pathological features in three cases of false aneurysm of the left ventricle are reported. In two instances the condition developed after myocardial infarction, and in the third case a mycotic pseudoaneurysm developed after purulent pericarditis. All three patients were in intractable heart failure before urgent operation. The correct diagnosis was established preoperatively by angiography. In all three cases the aneurysms were successfully resected and the left ventricle reconstructed. An aggressive surgical approach is warranted in the management of this lesion.
 ...
PMID:False aneurysm of the left ventricle. Surgical treatment. 70 62

A 57-year-old woman, treated for a large anterior transmural myocardial infarction, was readmitted after 8 weeks because of progressive cardiac failure. Chest X-ray showed cardiomegaly with an atypical cardiac silhouette. Two-dimensional echocardiography disclosed a large left ventricular pseudoaneurysm. The patient underwent resection of the false aneurysm with repair of the left ventricular wall and recovered gradually. Different methods for diagnosing pseudoaneurysm are discussed.
 ...
PMID:Echocardiographic findings in a patient with left ventricular pseudoaneurysm. 399 44

This 45-year-old white male was evaluated for congestive heart failure initially ascribed to a rapidly progressive cardiomyopathy. Both radionuclide ventriculography and echocardiography correctly identified a left ventricular pseudoaneurysm as the cause for heart failure. Thallium-201 scintigraphy, by demonstrating a large perfusion defect, suggested a large ostium of the pseudoaneurysm. Following resection of the false aneurysm, a Dacron prosthesis was required to close a large posterior wall defect. We conclude that both radionuclide ventriculography and echocardiography can independently demonstrate a left ventricular pseudoaneurysm. The combined noninvasive approach is able to delineate various anatomical aspects of the pseudoaneurysm and help in planning adequate surgical intervention.
 ...
PMID:Noninvasive evaluation of a left ventricular pseudoaneurysm: complementary role of echocardiographic and nuclear techniques. 683 53

Rupture of the left ventricle after myocardial infarction results either in sudden death from cardiac tamponade or, when pericardial adhesions are present, in bleeding that is confined to a limited space, which gradually expands as the blood flows through a small communicating orifice under high pressure, forming a false aneurysm. In three such patients a false aneurysm of the left ventricle after myocardial infarction was successfully treated by operation. The interval from the initiating event to the time of surgery averaged 10 months. Two of the patients had pericarditis and all presented at some stage of the illness with tachyarrhythmias and cardiac failure. All the patients survived operation and have improved functionally. Because of the propensity of false aneurysms to rupture, early diagnosis and aggressive surgical treatment are recommended.
 ...
PMID:Surgical treatment of false aneurysm of the left ventricle after myocardial infarction. 684 58

In 12 patients who had had composite replacement of the aortic valve and ascending aorta, infective endocarditis developed 2 months to 17 years after operation. Six patients had mechanical valves and 6 had biological ones (four homograft and two porcine valves). All patients needed operation because of shock, heart failure, persistent sepsis in spite of adequate antibiotic therapy, or the development of a paravalvular false aneurysm. The predominant microorganism was Staphylococcus. All 6 patients who had mechanical valves were found to have an abscess in the junction between the aortic annulus and the prosthesis; in patients who had biological valves the infection was limited to the leaflets in 3 (one homograft and two porcine valves) and leaflets and annulus abscess in 3 (three homograft valves). Operation consisted of radical resection of tissues suspected of being infected and reconstruction of the left ventricular outflow tract and of the surrounding structures with glutaraldehyde-fixed bovine pericardium. The aortic valve and ascending aorta were replaced with a new valved conduit. An aortic homograft was used in only 1 patient. There was only one operative death due to right ventricular infarction but most patients experienced serious postoperative complications. Operative survivors were followed up from 3 to 156 months (mean, 42 months). One patient died 35 months postoperatively due to bleeding complications of anticoagulation; 1 patient suffered a cardiac arrest at home 2 months after operation, sustained permanent cerebral damage, and died 4 months later. The remaining patients are asymptomatic from the cardiovascular viewpoint.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:Infective endocarditis in patients who had replacement of the aortic root. 806 44

We report an infant with intractable congestive heart failure caused by coarctation of the aorta, patent ductus arteriosus, atrial septal defect, and multiple muscular ventricular septal defects. He had received balloon angioplasty for dilating the aortic coarctation and a Gianturco coil for closing the ductus at a single therapeutic catheterization session at 4 months old. After balloon angioplasty, his heart failure had dramatically resolved. A false aneurysm and mediastinal hematoma were noted on the following day. The hematoma revealed total resolution 10 weeks later. He was asymptomatic throughout 12 months of follow-up.
 ...
PMID:False aneurysm and mediastinal hematoma: complications of simultaneous transcatheter therapy for coarctation of the aorta and patent ductus arteriosus in an infant. 1158 16

A 37-year-old male with acute complicated methicillin-sensitive Staphylococcus aureus mitral valve endocarditis underwent urgent valve replacement with a bileaflet prosthesis. The postoperative course was complicated with fever and heart failure. Echocardiography showed a large subannular false aneurysm of the left ventricle. Three weeks later resection and closure of the defect with a patch made from a cryopreserved thoracic aorta homograft were performed. The most significant aspects of this rare complication are commented on.
 ...
PMID:Staphylococcal postoperative subannular left ventricular false aneurysm. 1255 55

Between 1972 and 2000, left ventricular false aneurysm was diagnosed in 5 patients. These patients consisted of three man and 2 women, aged between 58 and 70 years. Clinical presentation was characterized by severe heart failure, complicating a posterior myocardial infarction, in 4 patients. Left ventricular angiography, has confirmed the false aneurysm in all patients. Three patients underwent surgical management, with good result in 2 cases (follow-up of 9 and 13 years), and an early postoperative death in one case. Two patients refused surgery and died suddenly. Ischemic myocardial disease, represent the most frequent etiology. Left ventricular false aneurysm prognosis should be improved by emergent surgical management, preventing fatal rupture.
 ...
PMID:[False left ventricular aneurysm: report of 5 cases]. 1261 53

A case of 47-year old woman operated on because of a chronic left ventricular false aneurysm caused by Staphylococcus aureus septicemia and endocarditis 8-years earlier is described. After septicemia was cured, clinical status improved so markedly that the patient refused to undergo recommended operation until onset of heart failure (NYHA III). She was operated on from the median sternotomy with the use of cardiopulmonary bypass. After pericardial adhesions were dissected free, the large left ventricular false aneurysm with severely calcified wall was found. The aneurysm was excised completely and its orifice closed with non-absorbable monofilament 3-0 suture. Postoperative course was complicated by epileptic attack accompanied by loss of consciousness and left hemiplegia on 4th day after surgery. Neurological symptoms regressed within 48 hours and on 12th postoperative day she was discharged from a hospital in a good clinical status.
 ...
PMID:[Chronic left ventricular pseudoaneurysm caused by Staphylococcus aureus septicemia accompanied by endocarditis]. 1619 30


1 2 Next >>