Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cardiac surgery to treat severe heart failure was of benefit to two patients with endomyocardial disease and hypereosinophilia-eosinophilic endomyocardial disease. Both patients had severe biventricular fibrosis with mitral and tricuspid regurgitation. One had predominant right ventricular disease and was treated by right ventricular endocardectomy with tricuspid and mitral xenograft valve replacement. The second patient's main haemodynamic problem was considered to be mitral regurgitation. His mitral valve was replaced by a Starr-Edwards prosthesis; endocardectomy was not performed. Though both patients had toxic confusional states for several weeks postoperatively there was distinct symptomatic and objective evidence of improvement which has been maintained for over 16 months. Previous reports of surgical treatment of 22 patients without eosinophilia (all of whom had endomyocardial resection) and three other patients with eosinophilia have shown equally encouraging results. There has been no evidence of recurrence or progression of heart damage in follow-up periods of up to seven years. It is concluded that cardiac surgery is an important advance in the treatment of endomyocardial disease in patients with or without an eosinophilia.
 ...
PMID:Successful surgical treatment of two patients with eosinophilic endomyocardial disease. 729 40

A case of transient tricuspid insufficiency in a newborn is reported. Cardiac catheterization performed at the age of two days because of cyanosis and cardiac failure, showed massive tricuspid incompetence, a normal tricuspid valve, increased diastolic volume of both ventricles valve, increased diastolic volume of both ventricles and depressed left ventricular ejection fractions. The clinical course has been satisfactory and at the age of four months repeated cardiac catheterization showed marked reduction of the size of both ventricles and improved left ventricular function; a small hypokinetic area of the left ventricle and a mild residual tricuspid incompetence, due to incomplete reversibility of the ischemic damage, were also documented. These findings suggest further considerations on therapeutic problems of transient tricuspid insufficiency and its outlook.
 ...
PMID:Transient tricuspid insufficiency of the newborn. Report of a case and further considerations. 746 40

Three cases of traumatic tricuspid insufficiency are reported. The most consistent clinical and noninvasive cardiovascular findings were: previous nonpenetrating thorax trauma; non holosystolic murmur which increased slightly during inspiration on standing; electrocardiographic patterns of right atrial enlargement and right bundle branch block; unusual bulge along the mid-left heart border, seen on chest x-ray examination suggesting ventricular aneurysm; striking right ventricular dilatation wit paradoxical movement of the ventricular septum on ECHO. Cardiac catheterization led to definitive diagnosis by demonstrating a massive tricuspid valve incompetence with "ventricularisation" of the right atrial pressure. Some dyskinetic areas of the right ventrice, most likely due to the full-thickness contusion of the miocardial wall, seen on the right cineangiography, confirmed the diagnosis. The long-term clinical and haemodynamic follow-up was useful for monitoring the evolution of the disease. Surgery should be recommended in the presence of right-sided heart failure not relieved by adequate medical treatment, in view of the low operative risk.
 ...
PMID:[Traumatic tricuspid insufficiency. Clinical and therapeutic aspects. Report of three cases (author's transl)]. 746 73

A 8-year-old girl with Ebstein's anomaly was operated on because of progressive heart failure caused by severe tricuspid regurgitation. At the operation, the tricuspid leaflets were found to be destroyed, and the annulus was very enlarged. The enlarged true tricuspid annulus was constricted using the DeVega method, and the tricuspid valve was replaced on the true annulus using a porcine valve. To avoid injury to the auriculoventricular bundle, the suture line was shifted to the false annulus at the portion close to the course of His' bundle. Postoperative course was uneventful in satisfactory condition. The role of valve replacement in the treatment of Ebstein's anomaly of the tricuspid valve is not only to improve valve formation, but also to secure the function of the right ventricle. It is ideal to replace the tricuspid valve on the true annulus provided that the injury to the His' bundle is safely avoided.
 ...
PMID:[A case of Ebstein's anomaly treated by tricuspid valve replacement]. 747 86

Umbilical venous waveforms by Doppler ultrasound are seen normally during fetal breathing movements. Each waveform extends two to four fetal cardiac cycles. During Doppler study of gross intrauterine growth retardation (IUGR) and twin to twin transfusion cases, single or double peaked umbilical venous waveforms were detected with each fetal cardiac cycle. Umbilical arterial Doppler study detected minimal, absent, or reverse diastolic flow. In these fetuses, the ratio of right and left ventricular diameters at the atrioventricular valve level was increased, and pulse-wave and color Doppler study showed tricuspid regurgitation. This tricuspid regurgitation caused reverse flow in the umbilical vein from the right atrium and inferior vena cava and produced characteristic venous waveforms. These umbilical waveforms were associated with gross IUGR or cardiac failure of the fetuses with perinatal morbidity and mortality.
 ...
PMID:Umbilical venous Doppler waveform without fetal breathing: its significance. 761 99

A 61-year-old woman was admitted for heart failure. She was diagnosed as corrected TGA with tricuspid regurgitation, perimembronous ventricular septal defect and atrioventricular block by echocardiography and cardiac catheterization. We chose tricuspid valve replacement with preservation of valve leaflet and subvalvular apparatus, direct closure of ventricular septal defect and implantation of permanent pacemaker (myocardial lead). Although IABP was needed for 24 hours, after that postoperative course was uneventful. It is preferable that tricuspid valve replacement with preservation of valve leaflet and subvalvular apparatus is applied to similar adult cases from standpoint of morphological structure.
 ...
PMID:[A case report of corrected TGA with ventricular septal defect, tricuspid valve regurgitation and atrioventricular block]. 763 26

Three cases with corrected transposition of the great arteries in patients older than 65 years are described. Two had atrial situs solitus and one atrial situs inversus. One had pulmonary valvular stenosis with valvular calcification and a small ventricular septal defect in association with ischemic heart disease. This patient died due to cardiac failure at the age of 80 years. The second case was associated with ventricular septal defect, atrial septal defect and pulmonary hypertension. The third patient presented with mild tricuspid regurgitation. Although this congenital heart malformation is theoretically compatible with normal life, few patients have long survival because of associated congenital defects or the subsequent development of tricuspid regurgitation or atrioventricular block.
 ...
PMID:[Corrected transposition of the great arteries in patients over 65]. 763 97

Uncontrollable severe mitral regurgitation is a frequent complication of end-stage cardiomyopathy, significantly contributing to heart failure in these patients, and predicts a poor survival. Although elimination of mitral valve regurgitation could be most beneficial in this group, corrective mitral valve surgery has not been routinely undertaken in these very ill patients because of the presumed prohibitive operative mortality. We studied the early outcome of mitral valve reconstruction in 16 consecutive patients with cardiomyopathy and severe, refractory mitral regurgitation operated on between June 1993 and April 1994. There were 11 men and five women, aged 44 to 78 years (64 +/- 8 years) with left ventricular ejection fractions of 9% to 25% (16% +/- 5%). Preoperatively all patients were in New York Heart Association class IV, had severe mitral regurgitation (graded 0 to 4+ according to color flow Doppler transesophageal echocardiography) and two were listed for transplantation. Operatively, a flexible annuloplasty ring was implanted in all patients. Four patients also had single coronary bypass grafting for incidental coronary disease. In four patients the operation was performed through a right thoracotomy because of prior coronary bypass grafting, and four patients also underwent tricuspid valve reconstruction for severe tricuspid regurgitation. No patient required support with an intraaortic balloon pump. There were no operative or hospital deaths and mean hospital stay was 10 days. There were three late deaths at 2, 6, and 7 months after mitral valve reconstruction, and the 1-year actuarial survival has been 75%. At a mean follow-up of 8 months, all remaining patients are in New York Heart Association class I or II, with a mean postoperative ejection fraction of 25% +/- 10%. There have been no hospitalizations for congestive heart failure, and a decrease in medications required has been noted. For patients with cardiomyopathy and severe mitral regurgitation, mitral valve reconstruction as opposed to replacement can be accomplished with low operative and early mortality. Although longer term follow-up is mandatory, mitral valve reconstruction may allow new strategies for patients with end-stage cardiomyopathy and severe mitral regurgitation, yielding improvement in symptomatic status and survival.
 ...
PMID:Early outcome of mitral valve reconstruction in patients with end-stage cardiomyopathy. 771 14

A patient with a severe liver injury and an acute cardiac failure due to a traumatic tricuspid valve failure is presented. During liver surgery, massive venous bleeding was caused by regurgitation of blood through the insufficient tricuspid valve. Right ventricular failure, leading to persistent hemodynamic instability, and caused by massive posttraumatic tricuspid regurgitation, has been treated with biological valve replacement. Diagnosis and management of posttraumatic tricuspid insufficiency are discussed.
 ...
PMID:Severe liver rupture and tricuspid valve rupture in a patient with multiple trauma. 776 Apr 22

A 30-year-old man, who had undergone Hardy's operation and the direct closure of an atrial septal defect for Ebstein's anomaly at age 9, was reoperated on by Carpentier's procedure for a long-standing tricuspid regurgitation. He required IABP support to wean from the cardiopulmonary bypass for the acute heart failure. Nonetheless, his postoperative course was uneventful. Echocardiography, nine months after the operation, showed a decrease in moderate residual regurgitation and an increase in the right ventricular inflow velocity, which were considered signs of an improvement in the right ventricular function and, furthermore, it showed an increase in the left ventricular volume and a marked improvement in the left ventricular ejection fraction. We consider that tricuspid regurgitation for many years result in a dysfunction in the right ventricle and, because of a decrease in the filling volume, in the left ventricle. For this reason, we should positively perform an operation without leaving tricuspid regurgitation as it is.
 ...
PMID:[A case of reoperation of Ebstein's anomaly with increased tricuspid regurgitation after Hardy's operation]. 776 50


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>