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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Survival studies were done on 36 children with cystic fibrosis and heart failure. Thirty percent did not survive the first four weeks, and the median survival for the group was between two and three months. By the end of the first year from the onset of failure, 74 percent had died and at 30 months, 87 percent had died.
West J Med 1975 Jun
PMID:Cystic fibrosis complicated by heart failure. 113 33

A 7-day old neonate presented with heart failure secondary to severe hypertension. The hypertension was discovered on day 9 of life. Control of his hypertension was a difficult problem eventually requiring continuous intravenous sodium nitroprusside therapy, and ultimately a nephrectomy. The nephrectomized specimen revealed renal artery stenosis, renal artery thrombosis and renal vein thrombosis. His eventual outcome was excellent.
West Afr J Med
PMID:Renovascular hypertension in a newborn: necessity of assessing blood pressure routinely. 147 66

A severely pre-eclampic patient developed peripartum cardiomyopathy and bilateral femoral emboli. Medical therapy for cardiac failure was commenced prior to delivery by Caesarean Section. Bilateral femoral embolectomy was performed on the sixth postpartum day.
West Indian Med J 1992 Jun
PMID:Peripartum cardiomyopathy and arterial embolism. 152 39

The frequency, clinical characteristics, and outcome of patients admitted with heart failure to a district general hospital in North-West London serving a population of approximately 155,000 was assessed over a six-month period. The number of patients with heart failure was determined by both a prospective ward survey and a retrospective study of all patient records with diagnostic codes for heart failure or pulmonary oedema. During those six months, 2,877 patients were admitted to the medical and geriatric services of whom 140 (4.9%) had heart failure. Only 29 patients in heart failure were under the age of 65 years. In 86 patients the mode of presentation was acute pulmonary oedema. Fifty-two (37%) patients had an arrhythmia at the time of admission of whom 48 had atrial fibrillation. An electrocardiogram, a chest X-ray, and an echocardiogram were performed in 137, 136, and 81 patients respectively. The aetiology of heart failure was considered to be coronary artery disease (41%), valve disease (9%), hypertension (6%), cor pulmonale (4%), a dilated cardiomyopathy (1%), congenital heart disease (1%), thyrotoxicosis (1%), and unknown (36%). During the period of hospital stay 42 patients (30%) died; a further 20 patients (14%) died in a one-year follow-up. In a district general hospital heart failure is a common reason for admission and patients remain in hospital for a considerable time. Arrhythmias are commonly associated with heart failure. The prognosis is poor and the hospital mortality high. The management of heart failure is an important consideration in allocating hospital resources in a district general hospital.
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PMID:Heart failure in a district general hospital. 842 54

Congestive heart failure is a common syndrome with high mortality in its advanced stages. Current therapy includes the use of vasodilator drugs, which have been shown to prolong life. Despite current therapy, mortality remains high in patients with severe heart failure. Potent new inotropic vasodilators have improved ventricular performance but have not prolonged life in patients with end-stage heart failure. Serious arrhythmias are implicated in the sudden deaths of 30% to 40% of patients with severe heart failure, but the benefits of antiarrhythmic therapy have not been established. Upcoming trials will address this question. Ventricular remodeling and progressive dilatation after myocardial infarction commonly lead to congestive heart failure; early unloading of the ventricle with an angiotensin-converting enzyme inhibitor may attenuate these events. These findings support the concept that angiotensin-converting enzyme inhibitors may be useful in managing heart failure of all degrees of severity, including left ventricular dysfunction and end-stage heart failure. Part of the damage that may occur with acute myocardial infarction, particularly in this era of thrombolysis therapy, is reperfusion injury, which may be mediated by oxygen-derived free radicals. Better knowledge of the mechanisms and treatment of myocardial infarction, the leading cause of congestive heart failure, may help prevent or attenuate the development of this syndrome.
West J Med 1991 Apr
PMID:Congestive heart failure. New frontiers. 167 3

The study was designed to determine the prevalence of alcoholism/problem drinking among emergency medical admissions. Of 203 emergency admissions to two medical wards, 18% were found to be problem drinkers, using the brief Michigan alcoholic screening test (MAST) questionnaire. Problem drinking was found in 31% of males and 5% of females. Most drinking was done with friends (77%) and at the "rum shop" (62%). Fifty-one per cent of problem drinkers started between the ages of sixteen and twenty years. Seventy per cent of all problem drinkers had a first degree family relative who drank compared to 28% of non-drinkers. A high prevalence of alcoholism (48%) was found among smokers. Housestaff detected just over half of male (56%) and female (60%) alcoholics who were MAST-positive. Medical diagnoses among MAST-positive patients were gastrointestinal (cirrhosis, pancreatitis and hepatitis) in 32%, neurological (delirium tremens, seizures and subdural hematoma) in 27% and cardiovascular (cardiomyopathy, heart failure and dysrhythmias) in 16%. The detected level of problem drinking is likely to cause significant morbidity, and allows an important opportunity for intervention. The use of questionnaire methods to screen for alcoholism needs further evaluation in the region.
West Indian Med J 1991 Jun
PMID:Questionnaire detection of problem drinkers among acute medical admissions. 189 23

The development of novel DA receptor agonists, with various receptor selectivities, has confirmed the therapeutic utility of modulationing the peripheral dopaminergic system as Goldberg proposed 30 years ago. In addition to the acute therapy of heart failure, circulatory shock, and renal dysfunction, for which low dose DA has been standard therapy for many years, there is substantial evidence that DA receptor modulation will make a significant contribution to the chronic therapy of hypertension and congestive heart failure. However, development of drugs with adequate oral bioavailability remains a priority if we are to exploit fully these therapeutic possibilities.
Proc West Pharmacol Soc 1990
PMID:Clinical use of dopamine receptor agonists. 198 Mar 63

A retrospective study of the primary causes of maternal deaths in the eclamptics treated in the Lagos University Teaching Hospital (LUTH) over a 20-year period, from 1st January 1967 through 31st December 1986, was carried out. During this period, a total of 845 cases of eclampsia were treated and 91 maternal deaths were associated with eclampsia or its complications. The maternal deaths included 66 predelivery and 25 postpartum eclamptics respectively. Most of the maternal deaths (n = 86) occurred in unbooked cases of eclampsia. The maternal mortality rate was 105/1000 eclamptic deliveries. The common primary causes of deaths in eclampsia in the LUTH during the period under study were renal failure (14.5%), cerebrovascular haemorrhage (12.7%), cardio-pulmonary failure (12.7%), disordered intravascular coagulation syndrome (DIC) (10.9%), and cardiac failure (8%). The Post Mortem Rate (PMR) in the dead eclamptics in the LUTH was 60%. Scrutiny of data suggested that many of the maternal deaths could have been avoided if the patients were brought to the hospital in good time for treatment.
West Afr J Med
PMID:The causes of maternal deaths in eclampsia in Lagos, Nigeria. 206 83

The association between proteinuria and congestive cardiac failure was investigated in patients with hypertensive heart disease, cardiomyopathy, rheumatic heart disease and cor pulmonale. In 33 such patients, proteinuria occurred before and after successful treatment of the cardiac failure. Overall there was a wide variation in the degree of proteinuria amongst the various groups and statistical analysis showed that the distribution of levels of proteinuria and the mean levels of proteinuria were statistically different between any two groups of patients, P = 0.05. Biopsy proven hypertensive nephrosclerosis was found to be a cause of heavy proteinuria which was in the nephrotic range in two such patients. Congestive cardiac failure due to hypertensive heart disease should be included in the differential diagnosis of massive proteinuria even in the absence of renal insufficiency.
West Afr J Med
PMID:The pattern of proteinuria in congestive cardiac failure due to common heart diseases. 206 87

An analysis of 500 consecutive pulmonary tuberculosis cases shows that lower lungfield tuberculosis occurs in 6.8 percent of the negroid population studied and therefore shows no racial predelection. The ratio of female to male involvement was 3:1. A clear association with young women and with pregnancy with or without other infections was demonstrated. Affected men were in the much older age group. Some association with diabetes and heart failure were also observed. The initial diagnosis of most of these patients was basal pneumonia or lung abscess. Therefore, the most useful clinical pointers were productive cough with or without haemoptysis unresponsive to various conventional antibiotics. The right base was most favoured and cavitation with fluid levels were frequent. We believe that the aetiological factors would include stress as could occur with pregnancies and poor basal tissue oxygenation due to diminished basal expansion in abdominal distension or cardiac failure.
West Afr J Med
PMID:Lower lungfield tuberculosis in a rural African population. 206 90


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