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Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

PVE is increasingly frequent and often lethal. The classic features of infective endocarditis may be absent early in the course of the illess. Therefore, patients with prosthetic heart valves and fever must be considered candidates for this infection until another cause for the fever can be established. Five to six blood cultures will document the persistent bacteremia of PVE in most cases. Treatment consists of parenteral penicillins for sensitive organisms plus valvular re-replacement for intractable heart failure mechanical malfunction of the valve, persistent sepsis, or multiple major emboli. In spite of aggressive therapy, the mortality remains high. Therefore, appropriate prophylaxis is warranted in patients with prosthetic valves who must undergo procedures that might lead to bacteremia.
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PMID:Prosthetic valve endocarditis. 62 May 13

Venous angiography of subcutaneous arteriovenous (A-V)) hemodialysis fistulas involves venous injection of radiographic contrast material which spreads throughout the venous system and into the arteries via the A-V anastomosis when blood flow to the extremity is temporarily occluded. Direct arterial cannulation is avoided. Subsequent restoration of blood flow with rapid sequential roentgenograms differentiates arteries from veins and identifies direction of fistula blood flow. A 44 month experience with 125 consecutive studies in 82 patients was performed with a 0.8% complication rate. Indications for fistulography included insufficient blood flow during dialysis (67%), cardiac failure (10%), aneurysms (6%), sepsis of undertermined site (6%) and other (77%). Roentgenographic findings identified vascular stenoses or occlusions (45%), malpositioned dialysis needles (11%), aneurysms (9%), unsuitable veins for dialysis (6%), absence of septic origin (5%), abnormal flow rates or patterns (5%), technically unsuitable studies (2%) and normal or baseline studies (17%). Information useful in planning clinical management of the patient was obtained in 88% of studies and fistular operations were performed in 65 patients (52%). Venous fistulography can be an effective and safe method of evaluating and planning correction of A-V dialysis fistula complications.
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PMID:Venous angiography and the surgical management of subcutaneous hemodialysis fistulas. 62 21

A 65 year old man developed endocarditis and septicemia due to Hemophilus aphrophilus, a Gram-negative coccobacillus. Renal rather than cardiac failure was the principal feature of his illness and renal biopsy was compatible with glomerulonephritis secondary to septicemia. Rapid recovery of renal function and improvement of the glomerular lesion followed antibiotic treatment of the septicemia. This case illustrates the renal damage that can occur in association with septicemia due to rarer infectious agents. As with more common organisms, specific antimicrobial therapy leads to rapid improvement of the nephropathy.
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PMID:Glomerulonephritis associated with Hemophilus aphrophilus endocarditis. 63 69

In a study of 310 burned patients, 27 of whom died, treated during a recent 3-year period, we have found that the following factors contributed to mortality: severity of the burn injury, advanced age of patients, race of the patients, cause of the burns, pre-existing medical problems, inadequate or inappropriate early resuscitative measures, and possible errors or oversights in the management of a few patients. Whether the patients were treated by general or plastic surgeons and whether the patients were "staff" or "private" appeared to have no significant bearing on survival or mortality. Death rates for the sexes were approximately equal. Deaths of patients who survived the immediate postburn period resulted mainly from pulmonary failure, renal failure, sepsis, and cardiac failure or from various combinations of these factors.
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PMID:Factors associated with deaths of burned patients in a community hospital. 66 Jun 96

Between 1965 and 1976 40 patients underwent valve replacement for active, infective endocarditis. The overall mortality rate was 32,5 per cent. Six patients died early (within 30 days) and 7 within the following 8 years. 11 patients developed paravalvular leckage. Eight of these 11 patients required reoperation. We suggest that all patients with active infective endocarditis who develop progressive heart failure, intractable sepsis or recurrent embolization should be subject to immediate valve replacement despite higher operative risk.
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PMID:[Surgical treatment of active infective endocarditis (author's transl)]. 69 94

The results of medial displacement osteotomy for unstable intertrochanteric fractures demonstrate that instability exists whenever there is lack of continuity of bone cortex on opposing surfaces of the 2 main fragments after reduction of the fracture. In 88 patients, 5 were lost to follow-up; 83 were reviewed personally by the authors at an average follow-up period of 27 months; the complication rate (both local and general) was high. Eight per cent showed non-union of the fracture; 13% developed deep infection (2 suffered from septicemia). Fifteen of 83 patients required a second operation. The mortality rate at 6 months was 13%, owing to heart failure, bronchopneumonia or thromboembolism. Of the 56 living, only 24 (43%) demonstrated a good functional result. Medial displacement osteotomy should be combined with a sliding screw-plate device. Without a sliding screw plate, medial displacement osteotomy for unstable intertrochanteric fractures of the femur may not be as successful as would appear from reports in the literature.
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PMID:The results of medial displacement osteotomy for unstable intertrochanteric fractures of the femur. 74 19

During the past decade 44 patients with active endocarditis, defined as valvular infection requiring operative intervention before completion of a planned course of antibiotic therapy, have been treated at Stanford University Medical Center. Twenty-seven patients had infection of a native valve (primary endocarditis) and 17 had infection of a previously implanted intracardiac prosthesis. In 91 per cent of cases urgent valve replacement was dictated by rapid hemodynamic deterioration and in the remainder by recurrent macroemboli or persistent sepsis. Various species of Streptococcus were the most common organisms encountered, followed by Staphylococcus aureus. Unusual bacteria were mostly limited to patients with prosthetic infections; Candida was seen in both groups. Aortic valve replacement was required in 80 per cent of patients. Operative mortality rates were 30 per cent in the group with primary disease and 24 per cent in the group with disease of the prosthetic valve. Most deaths were attributable to multiple system complications generated preoperatively and were unrelated to duration of preoperative antibiotic administration. Five-year survival rates for operative survivors were 68 per cent (primary) and 54 per cent (prosthetic). This experience illustrates the potential therapeutic benefit of operative intervention during active infective endocarditis complicated by severe heart failure or other life-threatening events.
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PMID:Operative treatment of active endocarditis. 77 23

During a six year period twelve patients with insulin dependent diabetes and end-stage renal failure received cadaveric kidney grafts. Eleven of the patients have previous to this been hemodialysed, one patient was transplanted before hemodialysis was necessary. The cumulative two year survival was thirty-seven per cent for the patients, and twenty-nine per cent for the kidney grafts. The average time of observation was eleven months, the motality was fifty per cent. The causes of death were acute myocardial infarction in two cases, sepsis in two cases, severe hypoglycemia in one case and unexpected sudden death in one case. The most prominent problems in the treatment of the diabetic patients after the renal transplantation were difficulties in the regulation of the diabetes, rejections, infections, cardiac failure and aggravation in pre-existing hypertension.
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PMID:Renal transplantation in patients with insulin requiring diabetes and renal failure. 78 7

In 214 patients with healed myocardial infarction an assessment was made of the prognostic value of risk factors relating to early postoperative cardiac decompensation which occurred in 50 cases. A significant influence was shown by age (greater than or equal to 75 years), pre-existing heart failure and load insufficiency, hypertension (greater than or equal to 180/95 mm Hg), advanced arteriosclerosis with cerebrovascular and renovascular symptoms, infections with fever or septicemia, emergency operations, lang-lasting surgery, decrease in blood pressure during operations (greater than or equal to 70 mm Hg systolic) and postoperative anemia (less than or equal to 3.5 millions erythrocytes/cmm). The postoperative cardiac failure took a lethal course in 60%. Pathogenetically, the discrepancy between O2-requirement and O2-supply in the previously damaged myocardium is of essential importance during the postoperative stress period.
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PMID:[Risk factors and pathogenesis of postoperative cardiac decompensation (author's transl)]. 81 21

Causes of death of 260 tumorous patients autopsied in 1974 were analyzed. Most common causes were inflammation and tumorous and non-tumorous organ insufficiencies; the others, in order of decreasing incidence, massive tumorous dissemination, infarct and haemorrhage. Pneumonia was predominating over the inflammatory causes although peritonitis and sepsis were also not rarely encountered. Death due to inflammation occurred most frequently in cases of myeloid-lymphoid, urogenital and gastro-intestinal tumours and in postoperative states. The incidence of insufficiencies due to tumorous or non-tumorous origin differed but slightly. Of the various organ insufficiencies, massive hepatic metastases, occlusion of the biliary duct and cardiac failure were the most common. In cases of tumors of the small pelvis, compression of the ureters led most often to death. Massive dissemination was observed most of all in breast and ovarian carcinomas. Myeloid-lymphoid tumors led to death through extensive organ infiltration in about one thirds of the cases. After hearth infarction, venous thrombosis was often followed by pulmonary embolism, however, coronary occlusion was also not rare. Death due to haemorrhage originated from acute or chronic ulcers of the gastrointestinal tract or from vascular invasion of tumors in the head and neck regions or from thrombocytopaenia induced by cytostatics.
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PMID:[Causes of death in cancer patients]. 92 45


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