Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

ECG was recorded in 38 patients with achalasia of the esophagus before, during and after pneumatic dilatation. During the dilatation both marked increases as well as decreases of heart frequency were observed. The mean values of all patients remained virtually unchanged. The most frequent type of arrhythmia were ventricular extrasystolies (16 patients), whereas supraventricular extrasystolies (4 patients), second degree-av-block (2 patients) and av-dissociation (1 patient) occured infrequently. In none of our patients arrhythmia was critical, even in a patient with preexisting cardiac insufficiency. Thus, patients with achalasia of the esophagus are not endangered to a major degree by cardiac arrhythmia during pneumatic dilatation.
 ...
PMID:[Cardiac arrhythmia during pneumatic dilatation of achalasia of the esophagus (author's transl)]. 7 69

13 male patients suffering from arteriosclerotic heart disease and/or arterial hypertension were monitored continuously before and after vascular surgical procedures using an arrhythmia computer. Heart rate, paroxysmal supraventricular tachycardias, ventricular extrasystoles, ventricular tachycardias, ventricular fibrillation and prematurity index (QnQe/QTn) were recorded numerically. Ventricular arrhythmias were detected as follows preoperatively in 12 patients, after operation in all patients, paired ventricular extrasystoles or episodes of ventricular tachycardia were found in 5 cases before and in 7 after operation, ventricular fibrillation in one case. The incidence of ventricular dysrhythmias increased significantly (p less than 0.05) early after operation, as did the heart rate during the observed postoperative period (p less than 0.001). The prematurity index dropped below 1.0 during the two days following operation. This differed significantly from the preoperative value (p less than 0.05). The incidence of ventricular extrasystoles was related to postoperative myocardial infarction and heart failure (p less than 0.01), which occurred in 6 cases, with a lethal outcome in three. Only occasionally controlled by trained staff in a normal surgical ward the "Servomed Dysrhythmiemonitor" yielded reliable numerical results during the main part of the monitored period. In two cases it led to immediate detection and rapid institution of treatment of severe tachyar rhythmias.
 ...
PMID:[Postoperative cardiac arrhythmias (author's transl)]. 8 Sep 61

Ten patients with severe myxoedema were treated with regular increments of thyroxine. The urine aldosterone excretion rate and plasma-aldosterone level increased with each increasing dose of thyroxine. Two patients in whom the serum-aldosterone rose to abnormally high levels had cardiac failure which resolved when the thyroxine dose was reduced.
 ...
PMID:Aldosterone in myxoedema. 8 81

The study revealed the usefulness of the apexcardiogram in the assessment of the contractile state of left ventricle in cases of ventricular extrasystolia. The pre-ejection period/left ventricular ejection time (PEP/LVET) ratio and isovolumic contraction period (IVCP) are good parameters for demonstrating the postextrasystolic potentiation, the lack of which occurs in severe heart failure. PEP/LVET and IVCP are R-R-interval dependent in parasystolia. In the establishment of the postextrasystolic potentiation, the authors contribute an important role to the ventricular filling during the compensatory pause.
 ...
PMID:Significance of the apexcardiogram in non-invasive assessment of postextrasystolic potentiation. 8 17

75 patients aged under 70 years who had survived acute myocardial infarction complicated by both significant arrhythmias and cardiac failure were followed-up for 1 year in an attempt to identify features which suggest the likelihood of late death or reinfarction. Patients were carefully instructed in the identification and importance of possible prodromal symptoms and the availability of a mobile intensivecare ambulance service and a 24 h hospital control centre. Horizontal ST-segment depression or anginal pain on an exercise test done within 6 weeks of infarction was a useful predictor of late death. Routine twice weekly E.C.G. recordings taken by telephone transmitter at rest and after mild exertion resulted in the identification of significant arrhythmias in only 7 patients. 13 patients (17%) died, 5 of them instantaneously. 4 of the 13 patients and 22 of the 62 survivors reported "prodromal symptoms". Unreported prodromal symptoms were elicited retrospectively in 14 of the 62 survivors and from the relatives of 4 of the 13 patients who died. Thus, 35% of prodromal symptoms were not reported despite intensive patient education and counselling. The incidence of "prodromal symptoms" was no higher in patients who died than in those who did not die.
 ...
PMID:Predictors of reinfarction and sudden death in a high-risk group of acute myocardial infarction survivors. 8 97

We have carried out a quantitative analysis of the force-interval relationship of the human left ventricle and compared it to previous studies done in both intact subjects as well as isolated muscle. The characteristics of the force-interval relationship of the normal patient resembed those of normal isolated mammalian muscle (except when exposed to high levels of catecholamines). The relationship in group 2 (patients with increased left ventricular dimensions and normal pressure indices) resembled those obtained from isolated muscles from hypertrophied hearts. The relationship from group 3 (patients with increased left ventricular EDDs and depressed pressure indices, two of whom were in clinical heart failure) resumbled those induced in normal muscles exposed to high levels of catecholamines, and those obtained from experimentally induced heart failure. The force-interval relationships of the four patients who fell into the third group were strikingly different from the other groups. This suggests that the force-interval relationship may be useful to describe changes in the inotropic state of the patient's heart.
 ...
PMID:The force-interval relationship of the left ventricle. 8 82

During the period 1960 to 1978, 98 patients underwent intracardiac repair of Fallot's tetralogy after palliative operations. Preoperative symptoms were cyanosis, dyspnea, increased fatigue with squatting and hypoxic spells. The hemoglobin concentration varied from 19 to 22 g/100 ml. At correction only 65 of 95 shunts were patent and needed surgical closure. Seventeen early deaths occurred (19%), the main causes being cardiac failure and arrhythmia. One patient died 3 years after correction from pneumonia. The subjective clinical result was excellent or good in all surviving patients. At repeat heart catheterization in 26 patients a high percentage of residual ventricular septal defects and pulmonary stenosis/insufficiency was found. However, the majority of defects were of minimal haemodynamic significance, and so far did not seem to do harm to the patients' subjective function.
 ...
PMID:Correction of Fallot's tetralogy after palliative operations. 8 99

Carnitine concentration was measured in plasma, muscle, and dialysate before and after haemodialysis in patients with renal failure and in plasma and muscle of healthy controls. In eight of the nine patients carnitine concentration in muscle after haemodialysis was only 10% of the concentration in controls. Plasma-carnitine varied in patients before dialysis and in all of them was reduced by dialysis. The loss of carnitine into the dialysate (190--2100 mumol/treatment) greatly exceeded the normal loss in urine for most of patients, and was only partly compensated for. In some patients normal or high plasma-carnitine and low concentrations in muscle indicated that the carnitine-concentrating mechanisms in the muscle cell had failed. The reduction in carnitine will interfere seriously with normal cellular functions and this may help to explain the clinical syndrome of cardiomyopathy and cardiac failure which has been observed in some patients treated for a long time with intermittent haemodialysis.
 ...
PMID:Carnitine deficiency induced during intermittent haemodialysis for renal failure. 8 56

This study showed the effectiveness of magnesium sulphate during digitalis therapy complicated by ventricular hyperexcitability. 28 patients with cardiac disease and ventricular arrhythmias in heart failure were studied. Magnesium sulphate was given by slow intravenous infusion (30--50 mg/min) twice daily. The anti-arrhytmic action allowed treatment with digitalis until improvement in cardiac function was observed. The mechanism of the action of magnesium sulphate in digitalis--induced arrhythmias is discussed.
 ...
PMID:[Anti-arrhythmic effect of magnesium cations. Protection against ventricular excitability during cardiotonic therapy]. 9 53

In 9 patients with various forms of heart rhythms and rates, all of whom had a temporary pacemaker electrode inserted, several single premature ventricular contractions (PVC) with various coupling intervals (CI) were induced. The relative systolic area of the carotid pulse curve in the postextrasystolic beat was used as an indicator of the degree of postextrasystolic potentiation (PESP). A close correlation between PESP and CI was found only in sinus rhythm patients (r = -0.85). The patients with junctional and ventricular rhythms had no PESP regardless of CI or the degree of heart failure. Compensatory pause (CP) in these patients surprisingly related (r = 0.95) to heart rate, slower rates having a shorter relative CP.
 ...
PMID:The relation of heart rhythm to postextrasystolic potentiation. 9 14


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>