Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018801 (heart failure)
 72,216 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The results of recent studies favor the immunological theory of the pathogenesis of chronic heart failure (CHF). In this connection, of particular interest is a search for possible causes of cytokine hyperactivation in patients with CHF of ischemic etiology, one of which may be viral infection. The aim of the study was to evaluate the impact of herpesvirus simplex (HVS), cytomegalovirus (CMV), Chlamydia pneumoniae on the activation of cytokines in patients with CHF of ischemic etiology. Ninety patients with CHF of ischemic etiology were examined. After comprehensive study, the patients were divided into 2 groups: 1) Functional Class (FC) I-II CHF and 2) FC III-IV CHF Increases in the levels of proinflammatory cytokines (tumor necrosis factor-alpha, interferon-gamma and in the content of IgG and IgM to CMV and IgM to HVS were ascertained in patients with CHF of ischemic etiology. There were statistically significant correlations of the level of proinflammatory cytokines, CMV, and HVS with the FC of CHF and the echocardiographic indicators reflecting left ventricular systolic function.
 ...
PMID:[Effect of infectious factors on the activation of proinflammatory cytokines in chronic heart failure]. 2000 Jan 13

A 34-year-old woman entered the emergency room with abdominal pain in the right upper quadrant. Computed tomography scan showed a nutmeg liver suspected for increased venous pressure by thrombosis of the liver veins, Budd-Chiari malformation, or right-sided heart failure. Interestingly, the diagnosis was pelvic inflammatory disease complicated by the Fitz-Hugh-Curtis syndrome (FHCS). Pelvic inflammatory disease resulted from an ascended infection by Chlamydia trachomatis. FHCS was caused by perihepatitis defined as inflammation of the peritoneal capsule of the liver. Fast diagnosis and treatment is crucial. Therefore, we report a case of FHCS characterized by a nutmeg liver on computed tomography.
 ...
PMID:Fitz-Hugh-Curtis syndrome resulting in nutmeg liver on computed tomography. 3119 61


<< Previous 1 2