Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Tissue inhibitor of metalloproteinases 4 9.9
FOXH1 protein 9.9
ZFP28 9.9
dimethylglycine dehydrogenase precursor 9.9
ABCA5 protein 9.9
RNT4 9.9
Ral guanine nucleotide dissociation stimulator-like 2 9.9
Microfibril-associated glycoprotein 4 8.9
tryptophan rich basic protein 8.9
C6orf170 8.9
congenital heart disease 5 protein 8.9
ZNF359 8.9
NLRR4 8.9
ZNF302 8.3
THAP5 8.3
SYNPO2L 8.3
Iroquois homeobox protein 4 8.3
CSTF2T 8.3
CCDC11 8.3
cardiac sodium channel alpha subunit 8.3
ONECUT3 8.3
CMH2 8.3
jumonji domain containing 1C 8.3
PTPN11 protein 8.3
KIAA0205 8.3
SH3BGR 8.0
calsarcin-3 7.9
SH3BGRL2 7.9
hSPT6 7.9
ANKRD1 protein 7.9
GATA4 protein 7.7
AMP deaminase 1 7.7
CBLN2 7.7
TBX20 7.7
GALNT11 7.6
Plakophilin 2 7.5
PRKAR1 7.5
C21orf59 7.5
CCDC114 7.5
SLFN14 7.5
CYLC2 7.5
SERINC2 7.5
SPATA18 7.5
ZCCHC2 7.5
WDR37 7.5
NKX2-5 7.5
MKKS 7.4
Desmocollin 2 7.3
TRAF3 interacting protein 2 7.3
SCN5A protein 7.3
RDBP 7.3
MEGF8 7.3
MOSPD1 7.3
LAMB4 7.3
Lysyl oxidase-like 1 7.3
TRIM55 7.3
CCDC65 7.3
TALDO 7.3
THY28 7.3
FASTK 7.3
inter-alpha-trypsin inhibitor heavy chain H1 7.3
Receptor activity-modifying protein 3 7.3
RNA-binding motif 3 7.3
McKusick-Kaufman syndrome 7.2
NEXN 7.2
Mulibrey nanism 7.1
RelA-associated inhibitor 7.1
RAPGEF5 7.1
GPR22 7.1
Histone-lysine N-methyltransferase 7.1
XKR6 7.1
PLAC4 7.1
EVC1 7.1
RNA-binding motif protein 20 7.1
CMH4 7.1
TCTN3 7.1
NKX2-6 7.1
MYNN 7.1
palmdelphin 7.0
WRB 7.0
more...
Disease
Cancer of lymphatic and hematopoietic tissue 9.9
Antidromic atrioventricular re-entrant tachycardia 9.9
Double outlet right atrium 9.9
Congenital heart disease in pregnancy 9.9
Congenital vascular disease 9.9
Atrioventricular nodal disease 9.9
Left sided heart 9.9
CMD1O 9.9
Heart disease during pregnancy 9.9
heart disease 9.9
Chronic left-sided congestive heart failure 9.9
Hemorrhagic conjunctivitis 9.9
Symmetrical growth retardation 9.9
Right free wall accessory pathway 9.9
Acyanotic congenital heart disease 9.5
Candidal endocarditis 9.3
Carcinoid heart disease 9.2
Acrocephalopolysyndactyly 9.1
Cyanotic congenital heart disease 8.9
Fascicular Block 8.9
Isolated aortic stenosis 8.9
Advanced sleep phase 8.9
Hypertensive heart failure 8.9
CMD1D 8.9
Embolic infarction 8.9
Atrial bigeminy 8.9
Cardiac disease in pregnancy 8.9
Malignant neoplasm of trachea, bronchus and lung 8.9
Cardiac infection 8.9
Arterial infection 8.9
Pulmonary endarteritis 8.9
Congenital aortic regurgitation 8.9
hypertension with LV hypertrophy 8.9
Other forms of heart disease 8.9
Multiple Lentigines 8.9
Acute inferior myocardial infarction 8.9
Endocardial disease 8.9
Carcinoid crisis 8.9
Neonatal gangrene 8.9
blocked tear duct 8.9
hyperthyroid heart disease 8.7
myocardosis 8.6
Kaufman syndrome 8.5
Fascicular ventricular tachycardia 8.5
Round heart disease 8.5
Maternal phenylketonuria 8.4
Monomorphic ventricular tachycardia 8.4
Plastic bronchitis 8.3
Pulmonary valve disease 8.3
Other cardiomyopathies 8.3
Straight back syndrome 8.3
Postoperative pulmonary edema 8.3
Pericardial defect 8.3
Xp21-linked muscular dystrophy 8.3
pancreatic cancer stage 8.3
Thrombotic infarction 8.3
Chronic heart disease 8.3
INVM 8.3
Rheumatic valvular disease 8.3
Congenital heart disease 8.2
Accelerated idioventricular rhythm 8.1
Peripheral pulmonary artery stenosis 8.1
Congenital pulmonary vein stenosis 8.1
pentalogy of Fallot 8.0
pseudotruncus arteriosus 8.0
Mesenteric fibrosis 7.9
Mulberry heart disease 7.9
Drug-induced cardiomyopathy 7.9
Acute congestive heart failure 7.9
Hardikar syndrome 7.9
Carnitine palmitoyltransferase deficiency 7.9
Chronic Daily Headache 7.9
T-lymphocyte immunodeficiency 7.9
Hypoplastic left heart syndrome 7.9
Pulmonary artery thrombosis 7.7
Lone atrial fibrillation 7.6
Tetralogy of Fallot with absent pulmonary valve 7.6
Peripartum cardiomyopathy 7.6
Ruptured cerebral aneurysm 7.5
penta-X syndrome 7.5
more...
Symptom
Chest pain at rest 9.9
Central chest pain 8.9
Abnormal extension 8.9
Holosystolic murmur 8.9
Neonatal cyanosis 8.3
Chest wall tenderness 8.3
swollen prostate 8.3
Central cyanosis 7.9
abnormal bruising 7.9
Cardiac syncope 7.8
Activity intolerance 7.3
feeling of malaise 7.1
cardiovascular problem 6.9
Fetal tachycardia 6.9
Cardiac pain 6.9
S3 gallop 6.8
Respiratory dyskinesia 6.5
Chronic chest pain 6.5
cyanosis 6.4
Globus sensation 6.4
feeling faint 6.3
Intermittent fever 6.2
Osler's nodes 6.2
syncopal episodes 6.1
presyncope 6.1
cardiovascular disability 6.1
diastolic murmurs 6.0
Ortner's syndrome 6.0
prickling sensation 6.0
Massive edema 6.0
Fetal supraventricular tachycardia 6.0
syncope 5.9
Chest discomfort 5.9
Non-cardiac chest pain 5.8
precordial pain 5.7
loss of feeling 5.7
clubbing 5.6
Thoracic pain 5.5
prominent nose 5.5
regurgitation 5.4
Poor weight gain 5.2
Postoperative nausea 5.2
bigeminal 5.2
change in skin color 5.2
cardialgia 5.2
atypical chest pain 5.1
Regurgitation 4.9
Fetal bradycardia 4.9
Acute dyspnea 4.9
Labor pain 4.9
Orthostasis 4.7
hyperosmia 4.7
menopausal symptoms 4.7
cardiovascular impairment 4.7
Vaginal dryness 4.7
Roth spots 4.7
Exercise intolerance 4.6
asynergy 4.5
Cardiovascular symptoms 4.5
Periodic breathing 4.4
Acute chest pain 4.3
Multimorbidity 4.3
trigeminy 4.3
leg cramps 4.3
hemihypesthesia 4.3
nocturnal polyuria 4.2
orthopnea 4.2
chest pain 4.2
lightheadedness 4.2
Induced hypothermia 4.2
rales 4.1
angina 4.1
tachypnea 3.9
facial droop 3.9
CSR 3.9
Circling 3.9
giddiness 3.8
giddiness 3.8
Skin symptoms 3.8
hot flashes 3.7
more...
Drug
Ethylisothiourea 9.9
Succinic Acid 9.3
Peach kernel 8.9
Aventyl 8.3
MEDI-524 7.8
Docarpamine 7.5
Palivizumab 7.4
Accupro 7.1
Dimetapp 7.1
Nifekalant hydrochloride 6.9
Lazabemide 6.9
Quinidine gluconate 6.4
anti-RSV 6.4
Rotigaptide 6.3
Indecainide 6.2
Propafenone hydrochloride 6.2
Cytomel 6.2
Methergine 6.2
Propafenone HCl 6.1
Cytomel 6.1
Zinc gluconate 6.0
Flecainide acetate 5.9
Percocet 5.9
Flecainide acetate 5.8
Synthroid 5.8
Aldurazyme 5.7
SR 57746A 5.7
Beraprost 5.7
Aldurazyme 5.7
Dronedarone 5.6
Sapropterin dihydrochloride 5.5
Cefuzonam 5.5
Mellaril 5.5
Synthroid 5.4
Cefroxadine 5.4
Hetrazan 5.3
Arachidonic Acid 5.2
Fluspirilene 5.2
Alupent 5.2
ULR 5.1
Alupent 5.0
Bosentan 4.8
Bosentan 4.8
K201 4.8
Ludiomil 4.7
Pimobendan 4.7
Ludiomil 4.7
Digitalis 4.7
CZON 4.6
Quinate 4.6
Warfarin sodium 4.5
Lipitor 4.5
Cibenzoline 4.5
Nesiritide 4.5
Demerol 4.4
Treprostinil 4.4
Enoximone 4.4
Terguride 4.3
Regadenoson 4.3
Oxycon 4.3
Ibopamine 4.3
Cardizem CD 4.3
Bethanidine 4.2
Lipitor 4.1
Lipitor 4.1
Atropine sulfate 4.1
Methergin 4.0
TPV 4.0
AVC 4.0
Ibutilide 4.0
Perhexiline 4.0
Ioversol 4.0
Lercanidipine 4.0
Inderal 4.0
Plavix 3.9
Vena 3.9
Vena 3.9
Ketalar 3.8
Kaletra 3.8
Demerol 3.8
more...
Enzyme
4-N-trimethylaminobutyraldehyde dehydrogenase 6.7
BCKA 4.8
PPH 4.7
long-chain acyl-coenzyme A dehydrogenase 4.5
cholesterol 25-hydroxylase 4.4
proline racemase 4.3
arginyltransferase 4.3
cruzipain 4.1
SRR 3.8
thiaminase 3.8
CDH 3.7
dihydroxyacetone kinase 3.6
meprin 3.6
thiaminase 3.5
NMT 3.5
KAR 3.5
trypanothione reductase 3.4
alpha-L-iduronidase 3.3
kynureninase 3.3
phosphatidylinositol phospholipase C 3.3
AFR 3.2
methionine synthase reductase 3.2
glycerol-3-phosphate oxidase 3.2
procollagen C-proteinase 3.2
stilbene synthase 3.1
pantetheinase 3.1
AMP deaminase 3.0
stilbene synthase 3.0
CCS 3.0
PAH 3.0
DSR 3.0
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.9
diacylglycerol kinase 2.9
GRK2 2.9
IgA protease 2.9
alliinase 2.9
nicotinamide mononucleotide adenylyltransferase 2.9
CAD 2.9
CAD 2.8
PWD 2.8
CAD 2.8
guanidinoacetate methyltransferase 2.7
biliverdin reductase 2.7
diol dehydratase 2.7
CTD kinase 2.7
GRK5 2.7
acetoacetyl-CoA reductase 2.7
iodothyronine 5'-deiodinase 2.7
malonyl-CoA decarboxylase 2.7
LipA 2.7
arachidonate 5-lipoxygenase 2.6
ACE 2.6
ATP diphosphohydrolase 2.6
inosine triphosphatase 2.6
protein disulfide-isomerase 2.6
glycine N-methyltransferase 2.6
betaine-homocysteine methyltransferase 2.5
methylenetetrahydrofolate reductase 2.5
methioninase 2.5
methylenetetrahydrofolate reductase 2.5
GMT 2.5
angiotensin-converting enzyme 2 2.4
LPL 2.4
Omi/HtrA2 2.4
ScpA 2.4
NADH-cytochrome b5 reductase 2.4
lysine acetyltransferase 2.4
TSR 2.4
KLK7 2.4
phosphodiesterase 2.3
CLK1 2.3
kynurenine 3-monooxygenase 2.3
MCS 2.3
Lod 2.3
cinnamate 4-hydroxylase 2.2
acyl carrier protein synthase 2.2
pregnancy-associated plasma protein-A 2.1
carnitine acetyltransferase 2.1
uridyltransferase 2.1
endothelin-converting enzyme 2.1
more...
Compound
BC 75 9.9
L-Homocystine 8.9
2-hydroxybenzonitrile 7.9
Isoetharine 7.3
Nortriptyline hydrochloride 7.1
o-Coumaric acid 7.1
Gossypin 6.4
Flecainide 6.4
Disopyramide phosphate 6.3
Propafenone 6.2
Moricizine 6.1
MBTS 6.1
Azimilide 6.0
Methyl palmoxirate 6.0
Encainide 5.9
Procyclidine 5.8
Sotalol 5.7
Amiodarone hydrochloride 5.7
1-methylanthracene 5.6
NAMS 5.6
Regulin 5.5
Amiodarone 5.5
Allyl chloride 5.4
Cefroxadine 5.4
Ajmaline 5.3
Oxymetholone 5.3
PTMS 5.3
WIN 18,446 5.3
CHQ 5.2
Mesoridazine 5.2
Lanatoside C 5.1
MINA 5.1
Disopyramide 5.1
BNP 5.0
Cafestol 4.9
Dofetilide 4.8
Benznidazole 4.8
Benznidazole 4.8
Benznidazole 4.8
DHCA 4.7
Dothiepin 4.7
Carminomycin 4.7
Ergotamine tartrate 4.7
Lentizol 4.7
Carminomycin 4.7
Halofantrine 4.7
AHA 4.7
Diethylcarbamazine citrate 4.6
Pergolide 4.6
Salvarsan 4.6
Novex 4.5
Tricaine 4.5
EPA ethyl ester 4.5
Nortriptyline 4.5
Eplerenone 4.5
SVC 4.5
Sooner 4.4
cholest-5-en-3-one 4.4
propionyl-carnitine 4.4
Digoxin 4.4
Theaflavin 4.4
Dorzolamide 4.4
DCM 4.3
Homocysteine thiolactone 4.2
Maprotiline 4.2
Myricitrin 4.2
Betanin 4.2
Cardiol 4.2
BNS 4.2
Sildenafil 4.1
gamma-CEHC 4.1
Furazolidone 4.1
DPBS 4.1
Phenergan 4.1
Nifurtimox 4.1
Ibutilide 4.0
CPB 4.0
TCAP 4.0
EBT 4.0
Tolazoline 3.9
more...