Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018799 (
heart disease
)
34,133
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
2148
Mol
677
insulin
515
MRI
281
She
262
collagen
247
natriuretic peptide
239
Mal
230
CHD
206
hemoglobin
201
HDL
190
cytokine
168
nodal
158
cardiac muscle
149
renin
144
myosin
132
ATP
129
C-reactive protein
122
ICD
106
fibrinogen
105
phosphodiesterase
102
albumin
101
angiotensin II
99
Pol
97
reserved
90
Men
88
ACE
85
calcium channel
83
tumor necrosis factor
78
atrial natriuretic peptide
77
ATPase
77
TNF
76
gut
74
sarcomeric
70
IL-6
70
BNP
65
sodium channel
65
endothelin-1
62
creatine kinase
62
GATA4
62
endoplasmic reticulum
61
ASD
61
SCN5A
60
caspase-3
59
histone
58
MAPK
58
CD4
55
TGA
54
leptin
52
Gen
51
JAMA
51
superoxide dismutase
50
COPD
50
LDL receptor
48
endothelin receptor
48
calcineurin
47
NMR
47
thyroid hormone
47
San
46
CO2
45
myosin heavy chain
45
glycoprotein
44
vascular endothelial growth factor
44
somatostatin
44
X-linked
43
interleukin-6
43
growth hormone
43
ubiquitin
42
erythropoietin
41
chronic renal failure
41
chromosome 21
40
lactate dehydrogenase
40
Bcl-2
40
proteasome
39
prothrombin
39
Ang II
39
thrombin
39
fibronectin
39
thymus
38
serum albumin
38
more...
Disease
heart disease
34133
heart failure
3221
hypertension
3093
diabetes
2973
cancer
2357
stroke
2167
cardiovascular disease
1629
myocardial infarction
1482
cardiomyopathy
1431
coronary artery disease
1270
obesity
1208
myocardial ischemia
1099
pulmonary hypertension
1044
congestive heart failure
1022
ventricular septal defect
838
coronary heart disease
827
atherosclerosis
749
dilated cardiomyopathy
670
depression
669
atrial septal defect
655
endocarditis
616
ischemia
569
myocarditis
529
hypertrophic cardiomyopathy
494
ventricular fibrillation
455
Chagas
436
tumor
384
ventricular hypertrophy
379
acute myocardial infarction
375
aortic stenosis
361
type 2 diabetes
360
Down syndrome
352
lung disease
339
valvular heart disease
330
pneumonia
319
asthma
306
vascular disease
297
sepsis
282
breast cancer
280
chronic disease
279
flutter
277
chronic obstructive pulmonary disease
277
mitral regurgitation
274
atrioventricular block
273
Kawasaki disease
272
osteoporosis
264
renal disease
263
rheumatic heart disease
263
arthritis
262
supraventricular tachycardia
255
Alzheimer's disease
254
renal failure
250
Congenital heart disease
244
sepsis
244
infectious diseases
239
carcinoid
236
lung cancer
223
dementia
221
anemia
220
dysplasia
219
metabolic syndrome
218
HIV
217
tricuspid regurgitation
209
hyperlipidemia
205
hypercholesterolemia
205
mitral valve prolapse
200
right bundle branch block
191
right heart failure
189
Brugada syndrome
180
mental retardation
178
aortic regurgitation
177
long QT syndrome
177
heart block
175
cirrhosis
175
dyslipidemia
173
AIDS
172
mental retardation
171
vasculitis
164
mitral stenosis
164
epilepsy
163
more...
Symptom
syncope
600
anesthesia
463
angina
387
regurgitation
361
dyspnea
353
cyanosis
351
chest pain
337
pain
312
overweight
232
seizures
199
respiratory distress
148
fatigue
147
headache
121
hypothermia
105
diarrhea
100
weakness
90
dizziness
88
collapse
79
cough
73
vomiting
69
shortness of breath
67
hypotonia
62
discomfort
60
discomfort
59
spasm
51
nausea
50
analgesia
48
clubbing
47
flushing
47
exertional dyspnea
46
menopausal symptoms
46
wheezing
44
presyncope
44
hemoptysis
42
tachypnea
41
abdominal pain
41
insomnia
38
syncopal episodes
37
hepatomegaly
34
sleepiness
34
exhaustion
30
thinning
29
hypercapnia
28
cachexia
26
splenomegaly
24
atypical chest pain
24
snoring
23
back pain
23
hemiplegia
22
ataxia
22
anorexia
21
constipation
20
arthralgia
19
stigma
18
functional recovery
18
vertigo
17
erythema
16
asynergy
16
hot flashes
15
oliguria
15
hepatosplenomegaly
14
asthenia
14
lethargy
14
low back pain
14
myalgia
14
starvation
14
nausea and vomiting
13
Ill
13
hunger
13
rales
12
stridor
11
CSR
11
hyperoxia
11
ENT
10
precordial pain
10
paresis
10
agitation
10
tremor
10
lightheadedness
10
orthopnea
9
more...
Drug
Cardiovasc
1818
vitamin E
73
ascorbate
69
Dermatol
52
Monit
47
anti-RSV
41
Palivizumab
38
lysine
37
nitroglycerin
36
caffeine
32
ROS
30
ampicillin
29
ROC
26
Spectrum
26
Nephron
20
Dial
20
IFN-gamma
19
MAP
19
Digitalis
17
EPA
16
ENT
16
Dakar
16
CSF
14
Bosentan
13
IL-2
13
Bosentan
13
Estrogens
12
Simvastatin
12
Asthma
11
CPR
11
Leaf
11
CTA
10
Nephron
10
Dronedarone
9
Angiotensin II
9
Vitamin E
9
Alliance
8
Propofol
8
Diphenhydramine
8
NADH
7
Ethanol
7
EE2
7
Spectrum
7
Viagra
7
Vitamin K
7
Growth hormone
7
Vitamin A
6
ABC
6
Growth hormone
6
Norplant
6
niacin
6
ICI
6
Vena
5
Serum albumin
5
Activin
5
Parkin
5
Parkin
5
ACT
5
Atropine
5
Fraction
5
Vena
5
Metrizamide
5
Heme
5
ETS
5
Hypaque
5
Mutagen
5
Fentanyl
5
Albumin
5
Captopril
5
Premarin
4
CTX
4
Paraffin
4
TAC
4
Glucagon
4
Award
4
MEDI-524
4
ALA
4
Viagra
4
Frontal
4
Indomethacin
4
more...
Enzyme
renin
144
mitogen-activated protein kinase
121
ACE
120
protein kinase
108
phosphodiesterase
102
creatine kinase
82
ATPase
81
ERK
73
luciferase
66
superoxide dismutase
61
calcineurin
56
lactate dehydrogenase
46
catalase
44
proteasome
43
protein kinase C
43
AMP-activated protein kinase
39
caspase-3
39
PAH
37
thrombin
37
aspartate aminotransferase
34
CAD
34
CAD
34
CAD
34
alkaline phosphatase
31
alanine aminotransferase
30
ACS
29
focal adhesion kinase
29
tissue plasminogen activator
28
APC
28
NADPH oxidase
25
glutathione peroxidase
24
guanylate cyclase
23
AMPK
23
NADPH oxidase
23
thromboplastin
22
peroxidase
20
AMPK
19
NO synthase
18
trypsin
18
lipoprotein lipase
17
NOS
15
phosphoinositide 3-kinase
15
glutathione S-transferase
15
collagenase
14
CaMKII
14
CPR
13
MEK
13
urokinase-type plasminogen activator
13
reverse transcriptase
13
methylenetetrahydrofolate reductase
13
methylenetetrahydrofolate reductase
13
lipase
12
3-hydroxy-3-methylglutaryl coenzyme A reductase
12
CPT
12
RNA polymerase
11
caspase-9
11
MAP
11
xanthine oxidase
10
citrate synthase
10
pyruvate dehydrogenase
10
CD10
10
adenylate cyclase
9
PKG
9
phosphatidylinositol 3-kinase
9
GSK
9
CDH
8
pyruvate dehydrogenase
8
ATP synthase
8
LPL
8
GRK5
8
CYP3A4
8
PARP
8
cruzipain
8
diacylglycerol kinase
8
heme oxygenase
8
pyruvate dehydrogenase
8
meprin
7
endonuclease
7
GRK2
7
gamma-glutamyl transpeptidase
7
more...
Compound
Cardiol
4567
Clin
2595
Dec
2420
oxygen
1109
calcium
551
glucose
514
DNA
505
sodium
303
water
265
His
261
nitric oxide
230
potassium
224
creatinine
173
iron
161
CO2
140
acetate
139
ATP
129
salt
123
aldosterone
121
ethanol
114
Cholesterol
86
prostaglandin E1
83
Amiodarone
77
TNF
76
prostacyclin
71
phosphate
70
nitrogen
68
selenium
64
BNP
64
homocysteine
64
zinc
63
iodine
62
vitamin D
59
arginine
59
Optimal
56
ASA
55
Estrogen
54
sulfate
52
Estrogen
51
hydrogen
47
Pac
47
urea
47
Insulin
45
cysteine
43
noradrenaline
42
lysine
41
ADP
41
Thyroid
41
AHA
41
copper
41
serine
39
Isoproterenol
37
PAH
37
Verapamil
37
Verapamil
36
cAMP
36
Phe
35
PEP
33
threonine
33
Hearts
32
Hearts
32
caffeine
32
galactose
31
Flecainide
31
Angiotensin II
29
ACS
29
A 3
29
ACS
29
TOF
28
Ang II
28
DDD
28
nitrate
28
ADP
28
TSH
27
ADP
27
Digoxin
27
leucine
26
methionine
26
cadmium
26
cGMP
25
more...