Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018799 (heart disease)
34,133 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 2148
Mol 677
insulin 515
MRI 281
She 262
collagen 247
natriuretic peptide 239
Mal 230
CHD 206
hemoglobin 201
HDL 190
cytokine 168
nodal 158
cardiac muscle 149
renin 144
myosin 132
ATP 129
C-reactive protein 122
ICD 106
fibrinogen 105
phosphodiesterase 102
albumin 101
angiotensin II 99
Pol 97
reserved 90
Men 88
ACE 85
calcium channel 83
tumor necrosis factor 78
atrial natriuretic peptide 77
ATPase 77
TNF 76
gut 74
sarcomeric 70
IL-6 70
BNP 65
sodium channel 65
endothelin-1 62
creatine kinase 62
GATA4 62
endoplasmic reticulum 61
ASD 61
SCN5A 60
caspase-3 59
histone 58
MAPK 58
CD4 55
TGA 54
leptin 52
Gen 51
JAMA 51
superoxide dismutase 50
COPD 50
LDL receptor 48
endothelin receptor 48
calcineurin 47
NMR 47
thyroid hormone 47
San 46
CO2 45
myosin heavy chain 45
glycoprotein 44
vascular endothelial growth factor 44
somatostatin 44
X-linked 43
interleukin-6 43
growth hormone 43
ubiquitin 42
erythropoietin 41
chronic renal failure 41
chromosome 21 40
lactate dehydrogenase 40
Bcl-2 40
proteasome 39
prothrombin 39
Ang II 39
thrombin 39
fibronectin 39
thymus 38
serum albumin 38
more...
Disease
heart disease 34133
heart failure 3221
hypertension 3093
diabetes 2973
cancer 2357
stroke 2167
cardiovascular disease 1629
myocardial infarction 1482
cardiomyopathy 1431
coronary artery disease 1270
obesity 1208
myocardial ischemia 1099
pulmonary hypertension 1044
congestive heart failure 1022
ventricular septal defect 838
coronary heart disease 827
atherosclerosis 749
dilated cardiomyopathy 670
depression 669
atrial septal defect 655
endocarditis 616
ischemia 569
myocarditis 529
hypertrophic cardiomyopathy 494
ventricular fibrillation 455
Chagas 436
tumor 384
ventricular hypertrophy 379
acute myocardial infarction 375
aortic stenosis 361
type 2 diabetes 360
Down syndrome 352
lung disease 339
valvular heart disease 330
pneumonia 319
asthma 306
vascular disease 297
sepsis 282
breast cancer 280
chronic disease 279
flutter 277
chronic obstructive pulmonary disease 277
mitral regurgitation 274
atrioventricular block 273
Kawasaki disease 272
osteoporosis 264
renal disease 263
rheumatic heart disease 263
arthritis 262
supraventricular tachycardia 255
Alzheimer's disease 254
renal failure 250
Congenital heart disease 244
sepsis 244
infectious diseases 239
carcinoid 236
lung cancer 223
dementia 221
anemia 220
dysplasia 219
metabolic syndrome 218
HIV 217
tricuspid regurgitation 209
hyperlipidemia 205
hypercholesterolemia 205
mitral valve prolapse 200
right bundle branch block 191
right heart failure 189
Brugada syndrome 180
mental retardation 178
aortic regurgitation 177
long QT syndrome 177
heart block 175
cirrhosis 175
dyslipidemia 173
AIDS 172
mental retardation 171
vasculitis 164
mitral stenosis 164
epilepsy 163
more...
Symptom
syncope 600
anesthesia 463
angina 387
regurgitation 361
dyspnea 353
cyanosis 351
chest pain 337
pain 312
overweight 232
seizures 199
respiratory distress 148
fatigue 147
headache 121
hypothermia 105
diarrhea 100
weakness 90
dizziness 88
collapse 79
cough 73
vomiting 69
shortness of breath 67
hypotonia 62
discomfort 60
discomfort 59
spasm 51
nausea 50
analgesia 48
clubbing 47
flushing 47
exertional dyspnea 46
menopausal symptoms 46
wheezing 44
presyncope 44
hemoptysis 42
tachypnea 41
abdominal pain 41
insomnia 38
syncopal episodes 37
hepatomegaly 34
sleepiness 34
exhaustion 30
thinning 29
hypercapnia 28
cachexia 26
splenomegaly 24
atypical chest pain 24
snoring 23
back pain 23
hemiplegia 22
ataxia 22
anorexia 21
constipation 20
arthralgia 19
stigma 18
functional recovery 18
vertigo 17
erythema 16
asynergy 16
hot flashes 15
oliguria 15
hepatosplenomegaly 14
asthenia 14
lethargy 14
low back pain 14
myalgia 14
starvation 14
nausea and vomiting 13
Ill 13
hunger 13
rales 12
stridor 11
CSR 11
hyperoxia 11
ENT 10
precordial pain 10
paresis 10
agitation 10
tremor 10
lightheadedness 10
orthopnea 9
more...
Drug
Cardiovasc 1818
vitamin E 73
ascorbate 69
Dermatol 52
Monit 47
anti-RSV 41
Palivizumab 38
lysine 37
nitroglycerin 36
caffeine 32
ROS 30
ampicillin 29
ROC 26
Spectrum 26
Nephron 20
Dial 20
IFN-gamma 19
MAP 19
Digitalis 17
EPA 16
ENT 16
Dakar 16
CSF 14
Bosentan 13
IL-2 13
Bosentan 13
Estrogens 12
Simvastatin 12
Asthma 11
CPR 11
Leaf 11
CTA 10
Nephron 10
Dronedarone 9
Angiotensin II 9
Vitamin E 9
Alliance 8
Propofol 8
Diphenhydramine 8
NADH 7
Ethanol 7
EE2 7
Spectrum 7
Viagra 7
Vitamin K 7
Growth hormone 7
Vitamin A 6
ABC 6
Growth hormone 6
Norplant 6
niacin 6
ICI 6
Vena 5
Serum albumin 5
Activin 5
Parkin 5
Parkin 5
ACT 5
Atropine 5
Fraction 5
Vena 5
Metrizamide 5
Heme 5
ETS 5
Hypaque 5
Mutagen 5
Fentanyl 5
Albumin 5
Captopril 5
Premarin 4
CTX 4
Paraffin 4
TAC 4
Glucagon 4
Award 4
MEDI-524 4
ALA 4
Viagra 4
Frontal 4
Indomethacin 4
more...
Enzyme
renin 144
mitogen-activated protein kinase 121
ACE 120
protein kinase 108
phosphodiesterase 102
creatine kinase 82
ATPase 81
ERK 73
luciferase 66
superoxide dismutase 61
calcineurin 56
lactate dehydrogenase 46
catalase 44
proteasome 43
protein kinase C 43
AMP-activated protein kinase 39
caspase-3 39
PAH 37
thrombin 37
aspartate aminotransferase 34
CAD 34
CAD 34
CAD 34
alkaline phosphatase 31
alanine aminotransferase 30
ACS 29
focal adhesion kinase 29
tissue plasminogen activator 28
APC 28
NADPH oxidase 25
glutathione peroxidase 24
guanylate cyclase 23
AMPK 23
NADPH oxidase 23
thromboplastin 22
peroxidase 20
AMPK 19
NO synthase 18
trypsin 18
lipoprotein lipase 17
NOS 15
phosphoinositide 3-kinase 15
glutathione S-transferase 15
collagenase 14
CaMKII 14
CPR 13
MEK 13
urokinase-type plasminogen activator 13
reverse transcriptase 13
methylenetetrahydrofolate reductase 13
methylenetetrahydrofolate reductase 13
lipase 12
3-hydroxy-3-methylglutaryl coenzyme A reductase 12
CPT 12
RNA polymerase 11
caspase-9 11
MAP 11
xanthine oxidase 10
citrate synthase 10
pyruvate dehydrogenase 10
CD10 10
adenylate cyclase 9
PKG 9
phosphatidylinositol 3-kinase 9
GSK 9
CDH 8
pyruvate dehydrogenase 8
ATP synthase 8
LPL 8
GRK5 8
CYP3A4 8
PARP 8
cruzipain 8
diacylglycerol kinase 8
heme oxygenase 8
pyruvate dehydrogenase 8
meprin 7
endonuclease 7
GRK2 7
gamma-glutamyl transpeptidase 7
more...
Compound
Cardiol 4567
Clin 2595
Dec 2420
oxygen 1109
calcium 551
glucose 514
DNA 505
sodium 303
water 265
His 261
nitric oxide 230
potassium 224
creatinine 173
iron 161
CO2 140
acetate 139
ATP 129
salt 123
aldosterone 121
ethanol 114
Cholesterol 86
prostaglandin E1 83
Amiodarone 77
TNF 76
prostacyclin 71
phosphate 70
nitrogen 68
selenium 64
BNP 64
homocysteine 64
zinc 63
iodine 62
vitamin D 59
arginine 59
Optimal 56
ASA 55
Estrogen 54
sulfate 52
Estrogen 51
hydrogen 47
Pac 47
urea 47
Insulin 45
cysteine 43
noradrenaline 42
lysine 41
ADP 41
Thyroid 41
AHA 41
copper 41
serine 39
Isoproterenol 37
PAH 37
Verapamil 37
Verapamil 36
cAMP 36
Phe 35
PEP 33
threonine 33
Hearts 32
Hearts 32
caffeine 32
galactose 31
Flecainide 31
Angiotensin II 29
ACS 29
A 3 29
ACS 29
TOF 28
Ang II 28
DDD 28
nitrate 28
ADP 28
TSH 27
ADP 27
Digoxin 27
leucine 26
methionine 26
cadmium 26
cGMP 25
more...