Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0018799 (heart disease)
34,133 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 2148 Mol 677 insulin 515 MRI 281 She 262 collagen 247 natriuretic peptide 239 Mal 230 CHD 206 hemoglobin 201 HDL 190 cytokine 168 nodal 158 cardiac muscle 149 renin 144 myosin 132 ATP 129 C-reactive protein 122 ICD 106 fibrinogen 105 phosphodiesterase 102 albumin 101 angiotensin II 99 Pol 97 reserved 90 Men 88 ACE 85 calcium channel 83 tumor necrosis factor 78 atrial natriuretic peptide 77 ATPase 77 TNF 76 gut 74 IL-6 70 sarcomeric 70 sodium channel 65 BNP 65 endothelin-1 62 creatine kinase 62 GATA4 62 endoplasmic reticulum 61 ASD 61 SCN5A 60 caspase-3 59 histone 58 MAPK 58 CD4 55 TGA 54 leptin 52 JAMA 51 Gen 51 superoxide dismutase 50 COPD 50 LDL receptor 48 endothelin receptor 48 calcineurin 47 NMR 47 thyroid hormone 47 San 46 CO2 45 myosin heavy chain 45 glycoprotein 44 vascular endothelial growth factor 44 somatostatin 44 X-linked 43 interleukin-6 43 growth hormone 43 ubiquitin 42 chronic renal failure 41 erythropoietin 41 Bcl-2 40 lactate dehydrogenase 40 chromosome 21 40 proteasome 39 Ang II 39 thrombin 39 prothrombin 39 fibronectin 39 thymus 38 interferon 38 serum albumin 38 PAH 37 apolipoprotein 37 HLA 36 IgA 36 NKX2-5 36 ferritin 36 atrial natriuretic factor 36 p38 35 troponin I 35 nitric oxide synthase 35 p53 35 CD8 35 IFN 34 Cor 34 TNF-alpha 34 adiponectin 34 CAD 34 mTOR 33 PEP 33 IL-10 32 vascular endothelium 32 catalase 32 dystrophin 32 AKT 32 TBX5 32 calmodulin 31 reductase 31 alkaline phosphatase 31 apolipoprotein B 31 FISH 31 estrogen receptor 30 PI3K 30 ROS 30 elastin 29 amyloid precursor protein 29 ACS 29 insulin-like growth factor 28 TOF 28 CRP 28 Alagille syndrome 28 ryanodine receptor 28 hemochromatosis 27 DDD 27 Lp(a) 27 catenin 27 ADP 27 chemokine 27 HMG-CoA reductase 26 phosphatase 26 aspartate aminotransferase 26 Holt-Oram syndrome 26 ERK 26 vasopressin 26 IL-8 25 glucagon 25 AMP 25 ERK1 25 VEGF 25 mineralocorticoid receptor 25 troponin T 25 ACC 25 inducible nitric oxide synthase 25 SARS 24 cardiac troponin I 24 ANP 24 connexin 24 angiotensin receptor 24 polypeptide 24 glutathione peroxidase 24 GSH 24 phospholamban 24 threonine 24 protein C 24 cardiac troponin T 24 matrix metalloproteinase 24 NKX2.5 23 tissue plasminogen activator 23 von Willebrand factor 23 apolipoprotein E 22 more...

Disease heart disease 34133 heart failure 3221 hypertension 3093 diabetes 2973 cancer 2357 stroke 2167 cardiovascular disease 1629 myocardial infarction 1482 cardiomyopathy 1431 coronary artery disease 1270 obesity 1208 myocardial ischemia 1099 pulmonary hypertension 1044 congestive heart failure 1022 ventricular septal defect 838 coronary heart disease 827 atherosclerosis 749 dilated cardiomyopathy 670 depression 669 atrial septal defect 655 endocarditis 616 ischemia 569 myocarditis 529 hypertrophic cardiomyopathy 494 ventricular fibrillation 455 Chagas 436 tumor 384 ventricular hypertrophy 379 acute myocardial infarction 375 aortic stenosis 361 type 2 diabetes 360 Down syndrome 352 lung disease 339 valvular heart disease 330 pneumonia 319 asthma 306 vascular disease 297 sepsis 282 breast cancer 280 chronic disease 279 flutter 277 chronic obstructive pulmonary disease 277 mitral regurgitation 274 atrioventricular block 273 Kawasaki disease 272 osteoporosis 264 renal disease 263 rheumatic heart disease 263 arthritis 262 supraventricular tachycardia 255 Alzheimer's disease 254 renal failure 250 Congenital heart disease 244 sepsis 244 infectious diseases 239 carcinoid 236 lung cancer 223 dementia 221 anemia 220 dysplasia 219 metabolic syndrome 218 HIV 217 tricuspid regurgitation 209 hypercholesterolemia 205 hyperlipidemia 205 mitral valve prolapse 200 right bundle branch block 191 right heart failure 189 Brugada syndrome 180 mental retardation 178 long QT syndrome 177 aortic regurgitation 177 cirrhosis 175 heart block 175 dyslipidemia 173 AIDS 172 mental retardation 171 vasculitis 164 mitral stenosis 164 epilepsy 163 bacterial endocarditis 161 plaque 158 liver disease 158 Wolff-Parkinson-White syndrome 153 left bundle branch block 151 rheumatic fever 150 septal defect 147 pulmonary embolism 145 pericarditis 144 bicuspid 142 prematurity 139 respiratory disease 128 immunodeficiency 128 influenza 127 hyperglycemia 126 pulmonary edema 123 malnutrition 123 West 122 Pulmonary arterial hypertension 122 pulmonic stenosis 121 cystic fibrosis 120 carcinoid syndrome 118 tuberculosis 118 Hypertrophic cardiomyopathy 117 rheumatoid arthritis 113 leukemia 111 virus infection 111 respiratory failure 109 cold 108 suicide 108 hypothyroidism 108 amyloidosis 107 ICD 106 systemic lupus erythematosus 102 developmental delay 101 hernia 101 pericardial effusion 100 cognitive impairment 99 idiopathic dilated cardiomyopathy 99 hyperthyroidism 98 DiGeorge syndrome 97 diabetic cardiomyopathy 97 bronchopulmonary dysplasia 96 hypertensive heart disease 95 sleep apnea 94 primary pulmonary hypertension 93 emphysema 91 cleft palate 90 bacteremia 87 left ventricular failure 86 bronchiolitis 85 peripheral vascular disease 85 alcoholism 85 mental illness 83 migraine 82 prolapse 82 metastases 80 Edwards 79 brain abscess 78 RSV infection 77 thrombocytopenia 76 Marfan syndrome 76 cor pulmonale 76 unstable angina 75 abortion 75 bronchitis 74 arteriosclerosis 74 sarcoidosis 74 ventricular dilatation 74 Infection 73 Infective endocarditis 73 genetic disorder 71 restrictive cardiomyopathy 71 bronchitis 71 transient ischemic attack 70 obstructive sleep apnea 70 sick sinus syndrome 70 preeclampsia 69 connective tissue disease 69 cerebral infarction 69 more...

Symptom syncope 600 anesthesia 463 angina 387 regurgitation 361 dyspnea 353 cyanosis 351 chest pain 337 pain 312 overweight 232 seizures 199 respiratory distress 148 fatigue 147 headache 121 hypothermia 105 diarrhea 100 weakness 90 dizziness 88 collapse 79 cough 73 vomiting 69 shortness of breath 67 hypotonia 62 discomfort 60 discomfort 59 spasm 51 nausea 50 analgesia 48 flushing 47 clubbing 47 exertional dyspnea 46 menopausal symptoms 46 wheezing 44 presyncope 44 hemoptysis 42 tachypnea 41 abdominal pain 41 insomnia 38 syncopal episodes 37 sleepiness 34 hepatomegaly 34 exhaustion 30 thinning 29 hypercapnia 28 cachexia 26 atypical chest pain 24 splenomegaly 24 snoring 23 back pain 23 hemiplegia 22 ataxia 22 anorexia 21 constipation 20 arthralgia 19 stigma 18 functional recovery 18 vertigo 17 asynergy 16 erythema 16 hot flashes 15 oliguria 15 hepatosplenomegaly 14 starvation 14 lethargy 14 low back pain 14 asthenia 14 myalgia 14 hunger 13 nausea and vomiting 13 Ill 13 rales 12 hyperoxia 11 stridor 11 CSR 11 precordial pain 10 ENT 10 paresis 10 agitation 10 tremor 10 lightheadedness 10 memory loss 9 orthopnea 9 Sedation 9 sore throat 8 blurred vision 8 hoarseness 8 hot flushes 8 chills 8 dysarthria 7 chorea 7 hypocapnia 7 night sweats 7 decreased appetite 7 hypoproteinemia 7 pallor 7 chronic cough 7 polyuria 6 hopelessness 6 Regurgitation 6 acute abdomen 6 exertional angina 6 hypertonia 6 spasticity 6 cerebellar ataxia 6 fever of unknown origin 6 ophthalmoplegia 6 physical appearance 6 diastolic murmurs 5 bigeminal 5 Multimorbidity 5 pleuritic chest pain 5 dystonia 5 tonic-clonic seizure 5 rhinorrhea 5 numbness 5 anosmia 5 twitching 5 leg edema 4 S3 gallop 4 excessive sweating 4 joint stiffness 4 livedo 4 leg pain 4 Decreased activity 4 acute stress 4 polydipsia 4 intestinal bleeding 4 persistent cough 4 prominent nose 4 neuralgia 4 colic 4 paresthesia 4 chest tightness 3 cardiovascular impairment 3 giddiness 3 giddiness 3 cardiovascular problem 3 eds 3 Respiratory symptoms 3 blackout 3 sinus pressure 3 acute abdominal pain 3 Catch 3 Fetal tachycardia 3 Ortner's syndrome 3 bitter taste 3 nocturnal polyuria 3 leg cramps 3 apathy 3 productive cough 3 tingling 3 incoordination 3 Cardiac syncope 3 irregular bleeding 3 epigastric pain 3 tinnitus 3 acute pain 3 masculinization 3 limb pain 3 knee pain 3 Exercise intolerance 3 more...

Drug Cardiovasc 1818 vitamin E 73 ascorbate 69 Dermatol 52 Monit 47 anti-RSV 41 Palivizumab 38 lysine 37 nitroglycerin 36 caffeine 32 ROS 30 ampicillin 29 ROC 26 Spectrum 26 Nephron 20 Dial 20 IFN-gamma 19 MAP 19 Digitalis 17 ENT 16 EPA 16 Dakar 16 CSF 14 Bosentan 13 Bosentan 13 IL-2 13 Estrogens 12 Simvastatin 12 Leaf 11 Asthma 11 CPR 11 CTA 10 Nephron 10 Vitamin E 9 Angiotensin II 9 Dronedarone 9 Propofol 8 Diphenhydramine 8 Alliance 8 EE2 7 Spectrum 7 Vitamin K 7 Ethanol 7 Growth hormone 7 Viagra 7 NADH 7 Norplant 6 ICI 6 Vitamin A 6 Growth hormone 6 niacin 6 ABC 6 Parkin 5 Serum albumin 5 Vena 5 Atropine 5 Fraction 5 ACT 5 Vena 5 Activin 5 Heme 5 Hypaque 5 ETS 5 Mutagen 5 Fentanyl 5 Metrizamide 5 Albumin 5 Parkin 5 Captopril 5 Gel 4 Paraffin 4 Clopidogrel 4 MEDI-524 4 Premarin 4 CTX 4 Frontal 4 Indomethacin 4 CVA 4 Synthroid 4 Flecainide acetate 4 AHF 4 THF 4 MRC 4 Award 4 Viagra 4 TAC 4 lactose 4 Lovastatin 4 citric acid 4 Nebivolol 4 Iohexol 4 Azithromycin 4 Check 4 Raloxifene 4 ADM 4 Adriamycin 4 Iloprost 4 ALA 4 Glucagon 4 Flecainide acetate 4 PPA 3 Herceptin 3 Ringer's solution 3 Depo-Provera 3 Rosiglitazone 3 Bifidobacterium 3 Retinoic acid 3 NH3 3 Valsartan 3 AVC 3 Diurnal 3 Prednisone 3 DEX 3 Hypaque 3 Phentolamine 3 Tocopherol 3 Atenolol 3 Ranolazine 3 Aprotinin 3 uPA 3 Thioridazine 3 Inderal 3 Synthroid 3 Nesiritide 3 Ranolazine 3 Vicryl 3 CCL 3 IL-1ra 3 Enoximone 3 Ramipril 3 Beraprost 3 Norplant 3 PCP 3 Portal 3 Bivalirudin 3 Phenytoin 3 Sodium nitroprusside 3 Ranitidine 3 AmBisome 3 Amiloride 3 EPI 3 Pravastatin 3 Forskolin 2 Bayer 2 Conray 2 Wine 2 Android 2 Infliximab 2 Timolol 2 TTC 2 Cibenzoline 2 CDP 2 Luteinizing 2 Emodin 2 AZT 2 Zmax 2 Amoxicillin 2 Rituximab 2 FAD 2 MDS 2 more...

Enzyme renin 144 mitogen-activated protein kinase 121 ACE 120 protein kinase 108 phosphodiesterase 102 creatine kinase 82 ATPase 81 ERK 73 luciferase 66 superoxide dismutase 61 calcineurin 56 lactate dehydrogenase 46 catalase 44 protein kinase C 43 proteasome 43 caspase-3 39 AMP-activated protein kinase 39 PAH 37 thrombin 37 CAD 34 CAD 34 aspartate aminotransferase 34 CAD 34 alkaline phosphatase 31 alanine aminotransferase 30 focal adhesion kinase 29 ACS 29 APC 28 tissue plasminogen activator 28 NADPH oxidase 25 glutathione peroxidase 24 NADPH oxidase 23 guanylate cyclase 23 AMPK 23 thromboplastin 22 peroxidase 20 AMPK 19 trypsin 18 NO synthase 18 lipoprotein lipase 17 glutathione S-transferase 15 NOS 15 phosphoinositide 3-kinase 15 collagenase 14 CaMKII 14 CPR 13 methylenetetrahydrofolate reductase 13 methylenetetrahydrofolate reductase 13 reverse transcriptase 13 urokinase-type plasminogen activator 13 MEK 13 lipase 12 CPT 12 3-hydroxy-3-methylglutaryl coenzyme A reductase 12 RNA polymerase 11 caspase-9 11 MAP 11 pyruvate dehydrogenase 10 citrate synthase 10 xanthine oxidase 10 CD10 10 PKG 9 adenylate cyclase 9 phosphatidylinositol 3-kinase 9 GSK 9 GRK5 8 ATP synthase 8 CYP3A4 8 cruzipain 8 LPL 8 CDH 8 PARP 8 pyruvate dehydrogenase 8 pyruvate dehydrogenase 8 heme oxygenase 8 diacylglycerol kinase 8 GRK2 7 RNase 7 RNase 7 meprin 7 gamma-glutamyl transpeptidase 7 complex I 7 phospholipase A2 7 glyceraldehyde-3-phosphate dehydrogenase 7 PPH 7 acetylcholinesterase 7 PRA 7 glutathione reductase 7 caspase-1 7 alpha-galactosidase 7 endonuclease 7 AOR 6 paraoxonase 6 MMP 6 chymase 6 beta-glucuronidase 6 neuraminidase 6 caspase-8 6 phosphorylase 6 AST 6 paraoxonase 6 AMP deaminase 6 furin 6 angiotensin-converting enzyme 2 6 glyceraldehyde-3-phosphate dehydrogenase 5 alpha-glucosidase 5 transcriptase 5 monoamine oxidase 5 elastase 5 kallikrein 5 CPT 5 plasmin 5 glyceraldehyde-3-phosphate dehydrogenase 5 CCS 5 adenosine deaminase 5 succinate dehydrogenase 5 subtilisin 5 CPT 5 adenosine deaminase 5 cytochrome oxidase 5 proprotein convertase 5 glyceraldehyde-3-phosphate dehydrogenase 5 prostate-specific antigen 5 glyceraldehyde-3-phosphate dehydrogenase 5 DNase 5 chaperonin 4 myosin ATPase 4 aldehyde dehydrogenase 4 IKK 4 beta-galactosidase 4 malate dehydrogenase 4 calcium pump 4 lysyl oxidase 4 MCS 4 aldehyde dehydrogenase 4 glycerol-3-phosphate dehydrogenase 4 MIP 4 sulfatase 4 cholinesterase 4 hexokinase 4 PDE 4 phospholipase C 4 glycerol-3-phosphate dehydrogenase 4 trypanothione reductase 4 cholesterol acyltransferase 4 alpha-L-iduronidase 4 diaphorase 3 aldehyde dehydrogenase 3 NADH-cytochrome b5 reductase 3 NQO1 3 PAL 3 P-glycoprotein 3 lysozyme 3 farnesyltransferase 3 protein phosphatase 2A 3 neutrophil elastase 3 lactase 3 DNA polymerase 3 histone acetyltransferase 3 thyroid peroxidase 3 more...

Compound Cardiol 4567 Clin 2595 Dec 2420 oxygen 1109 calcium 551 glucose 514 DNA 505 sodium 303 water 265 His 261 nitric oxide 230 potassium 224 creatinine 173 iron 161 CO2 140 acetate 139 ATP 129 salt 123 aldosterone 121 ethanol 114 Cholesterol 86 prostaglandin E1 83 Amiodarone 77 TNF 76 prostacyclin 71 phosphate 70 nitrogen 68 selenium 64 homocysteine 64 BNP 64 zinc 63 iodine 62 arginine 59 vitamin D 59 Optimal 56 ASA 55 Estrogen 54 sulfate 52 Estrogen 51 Pac 47 urea 47 hydrogen 47 Insulin 45 cysteine 43 noradrenaline 42 ADP 41 copper 41 lysine 41 Thyroid 41 AHA 41 serine 39 Isoproterenol 37 Verapamil 37 PAH 37 Verapamil 36 cAMP 36 Phe 35 threonine 33 PEP 33 Hearts 32 caffeine 32 Hearts 32 Flecainide 31 galactose 31 ACS 29 ACS 29 Angiotensin II 29 A 3 29 ADP 28 Ang II 28 TOF 28 DDD 28 nitrate 28 TSH 27 Digoxin 27 ADP 27 methionine 26 cadmium 26 leucine 26 5-HT 25 6-12 25 AMP 25 GSH 25 Dial 25 mercury 25 GSH 25 tyrosine 25 cGMP 25 Sotalol 23 GMP 22 Nicotine 22 tryptophan 22 SEE 22 phosphorus 21 Resveratrol 21 Propafenone 21 A 1 21 alanine 21 Propranolol 21 MIT 20 barium 20 Sildenafil 20 MTT 20 MIT 20 H2O2 19 Propranolol 19 tryptophan 19 tryptophan 19 Mg2+ 19 DCM 19 tryptophan 19 nicotinamide 18 silver 18 ACh 18 hydroxyindoleacetic acid 18 Progesterone 18 PGE2 17 Guo 17 Guo 17 Hemoglobin 17 Warfarin 17 Lead 17 CoA 17 glutamate 16 MAP 16 Adenosine 16 Diabetol 16 EPA 16 Abbott 15 proline 15 valine 15 Heparin 15 Sodium 15 Vitamin D 15 bromide 15 CPB 14 BMC 14 PGE 14 DHA 14 Diabetol 14 coenzyme Q10 14 Adriamycin 13 glutamine 13 SDS 13 phosphocreatine 13 Off 13 nickel 13 formaldehyde 13 Fibrinogen 13 manganese 13 retinol 13 chromium 12 Ascorbic acid 12 PAP 12 PAS 12 DSM 12 boron 12 dUTP 12 ammonia 12 acrylamide 12 more...

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