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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The way of termination of pregnancy was retrospectively analysed in 95 pregnant women with heart and/or great vessels diseases, hospitalised in years 1989-1991 and 1995-1996 in the Department of Obstetrics and Perinatology of Pomeranian Medical Academy. The condition of cardiovascular system was assessed according to NYHA classification on admission and just before delivery with participation of an experienced cardiologist. Kind of heart disease, mode and period of delivery, perinatal cardiovascular symptoms, duration of delivery and duration of hospitalisation, weight and clinical condition of the newborns were taken under consideration. In more than half of cases (60%) cesarean sections were performed. Among the indications for elective cesarean section cardiological indications formed the dominant group (29.5%). During perinatal period deterioration of circulatory system sufficiency associated with increase of number of cesarean sections were observed.
Ginekol Pol 1997 Jul
PMID:[Labor in women with heart and great vessel diseases]. 959 82

Adrenomedullin is a potent vasodilator and natriuretic peptide that may an important role in cardiovascular disease. To investigate the role of adrenomedullin in the pathophysiology of congestive heart disease, plasma levels of adrenomedullin were measured in patients with congestive heart failure. Venous blood samples at rest were obtained before and after treatment from patients with congestive heart failure in New York Heart Association functional class II (n-23), III (n-26) and IV (n-14) and from normal subjects (n-30). Plasma adrenomedullin, endothelin-1,2, and atrial natriuretic peptide were determined by radioimmunoassay, plasma noradrenaline by radioenzymatic assay. Left ventricular ejection fraction was measured by echocardiography. The mean plasma level of adrenomedullin in normal subjects was 8.2 pmol/l, tended to be increased in patients with congestive heart failure those in class II (12.9 pmol/l) and were significantly increased in classes III and IV (21.3 and 29.9 respectively). Plasma adrenomedullin was correlated strongly with endothelin-1,2, atrial natriuretic peptide, and noradrenaline, and relatively weakly with left ventricular ejection fraction. Plasma adrenomedullin levels significantly decreased after treatment. These findings indicate that plasma levels of adrenomedullin are elevated in congestive heart failure and may be involved in the defense mechanism against further peripheral vascular resistance elevation in congestive heart failure.
Pol Arch Med Wewn 1998 Jan
PMID:[Levels of adrenomedullin in plasma of patients with chronic congestive heart failure]. 968 97

Sudden cardiac death due to ventricular arrhythmias remains a significant problem. In most studies about 50% of all death related to coronary artery disease and heart failure are sudden and unexpected and are caused by acute fatal ventricular tachycardia and fibrillation. Most of the patients suffering sudden cardiac death have some kind of structural heart disease but 80% of SCD events are associated with coronary artery disease, 10-15% with dilated and hypertrophic cardiomyopathy, and only small fraction with the less common disorders as valvular heart disease, ventricular dysplasia and cardiac involvement in sarcoidosis or amyloidosis. In some patients the anomaly responsible for sudden cardiac death is not structural but mainly electrical as in patients with the long QT syndrome, WPW syndrome or in patients with a proarrhythmic effect from antiarrhythmic drugs. In this review, data from clinical trials and other studies on on antiarrhythmic therapies have been evaluated in order to determine effective strategies for the prevention sudden cardiac death in high risk patients. Taken together with the mortality data routine prophylactic use of class I antiarrhythmic drugs in the patients survivors of acute myocardial infarction and patients with heart failure is associated with increased risk of death. Conversely beta-blockers are associated with significant reduction in nonfatal cardiac arrest in the short term trials and sudden cardiac death in long term trials. These benefits are likely due to relief ischemia, reduction of heart rate and maintenance favourable autonomic nervous system balance. Overall trial data on amiodarone suggests that this agent is effective in reducing the risk of death in survivors of cardiac arrest, post infarction patients, and patients with heart failure but the routine prophylactic use of amiodarone remains of uncertain efficacy. The physician who considers the use of antiarrhythmic medications in patients with ventricular arrhythmias must be aware of which arrhythmias are malignant or potentially malignant and which are benign and the decision to initiate antiarrhythmic therapy should be based on consideration of the patients absolute mortality risk.
Pol Merkur Lekarski 1999 Mar
PMID:[Antiarrhythmic agents in the prevention of sudden cardiac death]. 1036 92

The thyroid hormones exert effects on the heart and the peripheral circulation playing an important role in the regulation of the function of the sinoatrial node, the systolic and diastolic function of the myocardium and the peripheral resistance. Their act directly by influence on protein synthesis, the properties of cell membranes and indirectly by interactions with autonomic nervous system causing increase in cardiac output and decrease systemic vascular resistance. Applying thyroid hormone therapy to the treatment of various forms of heart disease is connected with the development of the knowledge about their mechanism of action.
Pol Merkur Lekarski 1999 Mar
PMID:[Thyroid hormones and the heart]. 1036 3

The aim of the study was to evaluate the relation between heart diseases and ischemic cerebral stroke. In addition to routine tests, echocardiographic examinations were performed in 70 patients with ischemic cerebral stroke and in 30 persons constituting the control group. It was found that heart diseases occurred in 70% of the patients in the group studied i.e. three times more frequently than in the control group. Heart disease confirmed by echocardiography and electrocardiography occurred more frequently in patients with cerebral infarct than in those with RIND. In the majority of cases cardiac valve diseases and/or atrial fibrillation were noted. It was found that in 14.3% of the patients studied, the results of the echocardiography indicated the need for modification of the treatment applied.
Neurol Neurochir Pol
PMID:[The relation between ischemic cerebral stroke and heart diseases]. 1039 20

Erythrocytosis, thrombocytopenia, platelets function defects, coagulation factors deficiencies are the main haematologic disorders in patients with cyanotic congenital heart disease. They are responsible for increased bleeding tendency and contraindication of anticoagulation. Phlebotomy in this group of patients should be recommended when erythrocytosis is accompanied by clinical symptoms. Excessive phlebotomy can lead to iron deficiency and cause hyperviscosity symptoms. The iron supplementation should be closely monitored.
Pol Merkur Lekarski 1999 Aug
PMID:[Hematologic disorders in patients with cyanotic congenital heart disease]. 1052 25

A sixty years old woman with amyloid heart disease has been presented. Postural hypotension was the main symptom in this case. Pneumonia and the developing congestive heart failure was the cause of death. Only the last echocardiographic examination: hypertrophied interventicular septum with a peculiar speckled appearance of myocardium, together with low voltage electrocardiography made possible to confirm this diagnosis. It was shown in this case, how difficult it is to diagnose amyloid heart disease. Low ejection fraction together with diastolic abnormalities is usually a forecast of bad prognosis.
Pol Arch Med Wewn 1999 Jun
PMID:[Amyloid heart disease diagnosed with echocardiography]. 1075 38

Samuel Rosen originator of the surgical procedure so called mobilization, was second only to Juliusz Lempert as one of the great modern discoverers of new surgical techniques in the treatment of otosclerosis. This was the result of a chance discovery during routine stapes mobility test of the ossiculat chain before fenestration. Rosen having had excellent scientific training and knowledge was well prepared to interpret accidental stapes mobility and so design a new surgical technique. This operation enabled thousands of patients with otosclerosis to regain their hearing. However, he did not receive widespread acclaim in his own country. He received many invitations from abroad, travelled to several countries around the world where he taught stapes mobility testing and demonstrated his surgical procedure. In 1957 he also visited Poland, where he was born. He did not however limit himself to microsurgery of the ear. He created a group of international scientists who on the basis of investigations carried out by some of them, in the quiet noiseless African bush demonstrated that not only hearing is protected and the ageing process of this sensory organ delayed but also the development of arteriosclerosis is slowed down that which is the root cause of more and more cases of heart disease which among other factors can be attributed to the noisy stress ridden world we live in. After much success and fame which he achieved throughout the world, the American Medical Association awarded Sam Rosen a gold medal in 1967. But this too was not widely accepted by all his colleagues in his own country. He died in 1981 in China.
Otolaryngol Pol 1999
PMID:[Samuel Rosen (1897-1981): the originator of stapes mobilization]. 1076 30

The management of arrhythmias during pregnancy is, in principle, similar to that in nonpregnant patients, however, special consideration must be given, to avoid adverse fetal effects. In pregnant women without organic heart disease, no drug therapy is usually needed for the management of supraventricular or ventricular premature beats, but potential stimulants, such as smoking, caffeine, and alcohol should be eliminated. In patients with mitral valve prolapse beta blocker may be preferred drug. In pregnant patients with organic heart disease, paroxysmal atrial or ventricular tachycardia may induce hemodynamic changes with consequences to the fetus. In paroxysmal atrial tachycardia vagal stimulation maneuvers should tried and, if this is not effective, adenosine or beta-adrenergic blocking agents should be used. Alternatively, verapamil may be given. In pregnant with atrial fibrillation, the goal of treatment is conversion to sinus rhythm or control of the ventricular rate by digoxin. Synchronized electrical cardioversion may become necessary when signs of cardiac decompensation or hypotension were developed. Ventricular arrhythmias may occur in the pregnant women with cardiomyopathy, valvular heart disease, mitral valve prolapse and congenital Q-T prolongation. Termination of ventricular arrhythmias can usually be achieved by intravenous lignocaine or procainamide or by electrical cardioversion. To prevent recurrences, quinidine can be used if the arrhythmia was not induced by QT prolongation or procainamide.
Pol Merkur Lekarski 2000 Aug
PMID:[Treatment of cardiac arrhythmia in pregnant women]. 1108 13

53 female patients who informed the obstetrician about their cardiological problems were examined. In 44 cases the heart defects were diagnosed, in 39 cases of the congenital origin. In 20 patients the shunt congenital heart disease were recognized, in 13 cases the valvular defects, in 6--Fallot Syndrome and in the single cases tricuspid atresia, pulmonary atresia, Ebstein anomaly were observed. The next 9 patients were diagnosed as: in 4 cases hyperthrophy cardiomyopathy, in 2 cases the post myocarditis status, in 2 cases complete atrioventricular block and in 1 case WPW syndrome. The analysed women were pregnancy together 98 times, finished the delivery in 86 times. The physiological delivery were observed in 53 cases. 3 neonates died in the first day of live, 6 children were born prematured. Among 83 newborns who alived 7 required intensive care. The congenital heart diseases was diagnosed in 4 children--the atrial septal defect, pulmonary stenosis, coarctation of the aorta and mitral valve malformation were seen. Two children of the mothers with hyperthrophy cardiomyopathy have the same cardiological problems. The child of mother with congenital aortic stenosis suffered from the anal atresia and agenesis of the kidney.
Ginekol Pol 2000 Oct
PMID:[Reproduction problems in women with cardiovascular diseases]. 1114 32


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