Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors analysed clinically 108 patients (61 males and 47 females), aged below 50 years treated at the department of neurology, because of acute cerebral ischaemia. Attention is called to risk factors such as arterial hypertension, heart disease, atherosclerosis, obesity and diabetes which may be the cause of earlier development of ischaemic changes in the central nervous system. In the analysed group in 18 cases cerebral thrombosis, in 23 cases embolism, in 31 cerebral circulatory failure were diagnosed. In 36 cases the cause could not have been established.
Neurol Neurochir Pol 1977
PMID:[Acute cerebral ischemic disease in patients under the age of 50]. 88 1

The aim of this study was to assess the diurnal variability of heart rate during VT. For the purpose of this investigation VT was considered to be a minimum of 3 consecutive ventricular beats in duration at a rate more than 100 bpm. From the group of 287 patients with VT during 24-hour ECG monitoring, a selection was made of 52 patients in whom episodes of monomorphic VT occurred in the day-time and night-time without any changes of the QRS morphology. Thirty one patients had ischemic heart disease, 10--dilated cardiomyopathy, 2--mitral valve prolapse and 10 patients had no evidence of heart disease. In these patients the rate of VT (HR-V), basic heart rate (HR-S) before VT, and coupling interval (CI) of VT initiating beat were measured during day-time and night-time. The mean VT rate was 170 +/- 34 bpm during day-time and 149 +/- 36 bpm during night-time (p < 0.001). The mean sinus rhythm rate was significantly (p < 0.001) greater during day-time (88 +/- 16 bpm) than at night (78 +/- 19 bpm). There was significant difference in the mean values of the CI between day-time and night-time (504 +/- 122 vs 589 +/- 181 ms). A significant correlation was noted between HR-V and HR-S at night (r = 0.73; p < 0.001) but not during day-time (r = 0.38). Thus, HR-V similarly as HR-S is greater during day-time than during night-time. Diurnal variability of HR-V may be related to changes in autonomic nervous system tone.
Kardiol Pol 1992 Nov
PMID:[Diurnal variability of heart rate during paroxysmal ventricular tachycardia]. 128 89

An unusual case of cyanotic heart disease in a 20-year-old male has been presented. Cyanosis was due to right to left shunt through direct right pulmonary artery--left atrium fistula. After successful operative ligation of the fistula, the patient got rid of cyanosis and is doing well.
Kardiol Pol 1992 Nov
PMID:[A case of direct right pulmonary artery-left atrium fistula]. 128 95

Electrophysiological tests were performed in 60 patients aged between 18 and 63 years (mean age 38 years), and divided into two groups: with mitral valve leaves prolapse syndrome, and without this abnormality, in whom no other heart disease was diagnosed. Refraction of the right atrium, atrio-ventricular node, and right ventricle was evaluated together with cardiac response to different types of electrostimulation. A supraventricular dysrhythmia (most frequently atrial fibrillation) has been produced in 17 patients (42.5%) with mitral valve leaves prolapse syndrome whereas in the control group the same was produced in 2 patients (10%). Programmed stimulation of the ventricles did not produce ventricular tachycardia in none patient of both groups. Multiple ventricular beats have been produced in 3 patients with mitral valve prolapse syndrome and pairs of ventricular beats in other 3 patients of this group. Results suggest that "arrhythmogenic tendency", especially supraventricular dysrhythmia is more frequent in patients with mitral valve prolapse syndrome than in the general population.
Pol Tyg Lek
PMID:[Programmed atrial and ventricular stimulation in patients with mitral valve prolapse--a personal experience]. 143 74

The purpose of the study was to assess the quality of life and opinions of heart transplant candidates about transplantation and to evaluate some psychological aspects of anticipation of the procedure. The study comprised 49 patients from the Department of Cardiac and Vascular Surgery according to a list of potential candidates from January 1991. The special questionnaire prepared by the authors was applied in the study. The main topics were: severity and treatment of heart disease, method of informing about necessity of operation and basics of transplantation, factors contributing to the ultimate decision, opinions about problems of donors and psychological aspects of disease and transplantation, especially anxiety and fear. 39 answers (34 men, 5 woman, mean age--49.6 years) were received, including 10 reports of patient's death. Respondents evaluated their compensation of illness as bad or average nearly in equal proportions, 48.3% and 51.7% respectively. They were treated in the intensive care units on average 2.6 times a year. 96.6% assessed highly the method of informing about heart transplantation, consisting of a private conversation with a physician. A similar proportion of respondents (93.1%) began to show concern about problems associated with this procedure. Up to 77.8% declared the desire of increasing their knowledge on that score emphasizing the significance of information coming from physicians. The majority of respondents were interested in postoperative management--but 40.4% stated that they did not know anything about it. 58.6% consent immediately after transplantation had been proposed by the physician.(ABSTRACT TRUNCATED AT 250 WORDS)
Kardiol Pol 1992 Oct
PMID:[Opinions and fears of patients waiting for heart transplantation. (results of questionnaire)]. 146 1

Multi-infarct dementia (MID) and dementia of the Alzheimer type (DAT) are the main syndromes in the elderly. This study aims at evaluating the possible differentiation of these syndromes on a clinical basis. The patient population consisted of demented patients hospitalized during the period April 1, 1988-September 30, 1990 at the Department of Cerebrovascular Diseases. The study included 40 patients with MID and 25 with DAT. The clinical diagnosis of dementia included medical history, neurological examination, psychiatric interview and laboratory diagnostic investigations. The severity of the dementia symptoms was rated by many rating scales and a battery of neuropsychological tests. This model of clinical procedure permitted for differential diagnosis between vascular and degenerative dementia, according to DSM-III-R criteria. Patients with multi-infarct dementia of the Alzheimer type did not differ significantly with regard to age, mean duration of cognitive impairment and level of education. In the DAT group women outnumbered men, and this was statistically significant. It should be emphasized, that a great majority of patients with cerebrovascular lesions developed early cognitive impairment, that means within the first year after stroke. In the MID group hypertension, heart disease and smoking were statistically more frequent than in the DAT group. For the preliminary evaluation the severity of cognitive impairment was quantified by Mini-Mental State and Dementia Scale. These scales showed that the degree of dementia was significantly greater in DAT patients as compared to MID patients, whereas the severity of depression assessed by Hamilton's Scale was mild and similar in both group.(ABSTRACT TRUNCATED AT 250 WORDS)
Neurol Neurochir Pol
PMID:[Clinical and differential diagnosis of multi-infarct dementia and Alzheimer's disease]. 152 70

We present a case of the rare coincidence of three mechanisms leading to development of congenital heart disease in intrauterine life: intrinsic defect of the development of the cardiac loop (dextrocardia), failure of normal expansion of the subpulmonary infundibulum (Fallot syndrome) and endocardial cushion defect (common atrium and common atrioventricular valve ). It was associated with partial viscera inversion. A 31-year old man with congenital cyanotic heart disease, and Blalock-Taussig anastomosis was admitted to the hospital due to symptoms of severe cardiac failure. On physical examination: systolic murmur, hepatomegaly, ascites, leg's edema and cyanosis were found. In ECG--atrial fibrillation with 3-d degree a-v block. Standard echocardiography revealed: dextrocardia, a large single atrium with ostia of pulmonary and systemic veins, single atrio-ventricular valve , large ventricular, Fallot-like septal defect. The papillary muscles were not visible in the left ventricle. Aorta and pulmonary trunk arose from morphological right ventricle. The patient died on the 3-rd day of hospitalization in the course of cardiac and respiratory insufficiency. Postmorten examination confirmed the diagnosis.
Kardiol Pol 1992 Apr
PMID:[Combined heart defects: tetralogy of Fallot, common atrium and a single atrioventricular valve diagnosed by echocardiography]. 164 Jun 69

Mitral flow was assessed by Doppler echocardiography in patients with systemic hypertension. The study was carried out on 40 patients (27 men and 13 women) aged 24-50 years, mean 43 years with essential hypertension stage II according to WHO classification. No patient had other heart disease or diabetes. All patients were randomly assigned to verapamil (20 patients) or propranolol (20 patients). The daily dose of verapamil was 60-120 mg, mean 80 mg and propranolol 120-180 mg, mean 140 mg. Pulsed Doppler studies in all patients were performed before the treatment and after 4-6 weeks of the treatment. Echocardiographic examination was performed with Hewlett-Packard 707020 A ultrasound system using 2.5 MHz transducer. Two dimensionally guided pulsed Doppler echocardiograms were recorded with sample volume positioned in the inflow area below the mitral annulus. The following Doppler parameters were measured: early diastolic flow velocity (EDF), late diastolic flow velocity (LDF) and their ratio (EDF/LDF) which represents the ratio of early and late diastolic flow velocity of left ventricular filling. The study has showed that before treatment the value of EDF, LDF and EDF/LDF ratio in both groups did not significantly differ. Heart rate and arterial pressure in patients with systemic hypertension after treatment with verapamil or propranolol were significant lower than before treatment. Treatment with verapamil caused significant increase of EDF from 61.2 to 78.2 cm/sek and increase EDF/LDF ratio from 1.02 to 1.30. While LDF values were not changed. In the group of patients treated with propranolol the values of EDF, LDF and ratio EDF/LDF were similar to those before treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
Kardiol Pol 1991
PMID:[Effects of verapamil and propranolol on the left-ventricular diastolic function in patients with primary arterial hypertension]. 176 83

To assess if the presence of false tendons (FT) in the left ventricle can be an independent factor increasing the risk of ventricular arrhythmias in apparently healthy subjects, we examined 38 persons aged 18-60 years in whom during echocardiographic examination we accidently found FT in the left ventricle. No other echocardiographic disorders were present. Physical examination, ECG and stress ECG showed no symptoms of heart disease. The only ischaemic heart disease risk factor was smoking in 20 persons (in 6--more then 20 cigarettes daily). 24-hours Holter monitoring revealed single supraventricular complexes in 9 persons (34.7%). We found ventricular arrhythmias in 6 persons (15.8%): 4 (10.5%) had single, unifocal ventricular complexes, 1 (2.6%) had more (up to 6 in one minute) ventricular complexes, and 1 (2.6%) had some ventricular couplets. We observed no ventricular arrhythmias in stress ECG. We conclude, that in apparently healthy subjects with FT the frequency of ventricular arrhythmias is not higher, then in the normal healthy population.
Kardiol Pol 1991
PMID:[False tendons in the left ventricle--an independent arrhythmogenic factor?]. 180 Aug 25

A case of a 34-year female patient with the isolated transposition of the great arterial trunks and mild atrioventricular (tricuspid) valve insufficiency is presented. The disease was diagnosed with non-invasive technique, particularly echocardiography. Cardiac disorders being usually concomitant with this syndrome (interventricular leak, pulmonary arterial wedge stenosis etc.) have been excluded by the aid of the contrast echographic technique and Doppler technique. The results of electrocardiographic records, which are usually helpful in the diagnosis of this abnormality have been completely useless in this case due to atypical ventricular depolarization vector pattern (QS complex in V1-V6 leads).
Pol Tyg Lek
PMID:[A case of isolated, corrected transposition of great arteries diagnosed with non-invasive techniques]. 184 65


1 2 3 4 5 6 7 8 9 10 Next >>