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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Serum activity of creatine kinase and creatine kinase-MB have been investigated in 129 patients of various etiology in overt heart failure. Elevations in CK-MB were found in 19 patients, most frequently in patients with inflammatory heart disease. We found no correlation between CK-MB activity in serum and the severity of heart failure. CK-MB elevation in patients with chronic heart failure may be interpreted as a sign of progressive as well as regressive processes in the myocardium.
Med Klin 1978 Dec 22
PMID:[Determination of creatine kinase and CK-MB in heart failure (author's transl)]. 72 68

P waves with a "dome and dart" configuration have been observed in patients with congenital and acquired heart disease while having arrhythmias of left atrial origin. This report describes a patient who has dome and dart P waves that appear to be neither ectopic nor associated with structural heart disease.
South Med J 1978 Dec
PMID:"Dome and dart" P waves. 72 45

Serum catecholamines (epinephrine, dopamine and norepinephrine) were measured two, four and six hours after open heart surgery. The ratios of stroke index (SI) and cardiac index (CI) to catecholamines (CA) were determined. Patients studied consisted of 27 with congenital and 14 with acquired heart disease. Extracorporeal circulation (ECC) time was longer than 90 minutes in 17 and shorter in 24 patients. SI and CI diminished in elder patients with congenital disease (Group Cg-ad), patients with acquired disease (Group Ac) and patients with a longer ECC time (Group L). Therefore, elder age and/or longer ECC time seems to be responsible to the lower indices. However, the ratios of the indices to CA showed that the lower indices indicated the poor response of the myocardium to CA in Group Ac and Group L. The response was larger in Group Cg-ad and the lower indices were related to lower serum CA level. It was concluded, therefore, that the indices of stroke volume and cardiac output had inverse correlation to ECC time, but not to age, namely, prolonged ECC compromised more severely the myocardium and resulted in the poor response of the myocardium to CA. Subsequently, to compensate for the poor response, serum CA levels were elevated probably to maintain due SI and CI in patients with prolonged ECC.
Jpn J Surg 1978 Dec
PMID:Relation of stroke and cardiac indices to serum catecholamines following open heart surgery. 73 52

The effect of double plasmaphoresis upon the central hemodynamics in 37 cases of pulmonary carcinoma was studied. Plasmaphoresis was aimed at the storage of an autologous transfusional medium to compensate the operative blood loss. Taking 400-500 cc of plasma does not cause any hemodynamic changes in patients without heart disease signs. The choice between surgical intervention and repeated plasmaphoresis should be made with regard to the time necessary for normalization of the circulatory parameters following plasmaphoresis.
Vestn Khir Im I I Grek 1978 Dec
PMID:[Hemodynamics in double plasmapheresis in lung cancer]. 74 90

A blood pressure measurement was part of a cardiovascular screening examination of 8397 middle-aged men taking part in the intervention section of the United Kingdom Heart Disease Prevention Project. Standardised training techniques reduced observer bias to acceptable limits in four out of a total of five observers. The time of day and room temperature both made significant differences to the blood pressure measurement. High room temperatures in particular apparently had a marked effect in reducing the level of blood pressure. There were consistent and large positive associations with increasing age and overweight. The survey revealed a poor degree of blood pressure control in the community at the time of screening--only 7% of the "hypertensive" population had their diastolic pressure controlled to below 100 mm Hg.
J Epidemiol Community Health (1978) 1978 Dec
PMID:Blood pressure measurement in the United Kingdom Heart Disease Prevention Project. 74 12

A case of trisomy 18, confirmed by G banded chromosome analysis, is reported in an eleven year old Australian girl. There is no cytogenetic evidence of mosaicism in the propositus or her parents. The patient's salient clinical features are severe mental and motor retardation with microcephaly, kyphoscoliosis and various congenital anomalies. She has very mild congenital heart disease. She has been totally institutionalised and has required constant medical care. Comparison of her condition with other long-term survivors with trisomy 18 reported in the literature, and also considered to be non-mosaic, reveals many similar features. However, no pattern emerges as to why these rare patients have survived.
J Ment Defic Res 1978 Dec
PMID:Trisomy 18 in an 11 year old girl. 74 27

We report 11 cases of bacterial endocarditis with muscular and articular manifestations seen over the past ten years. There was arthralgia in 7 cases, vertebral pain in 7 cases and myalgia in 3 cases. Arthritis consisted of a monoarthritis of the ankle in 2 cases and oligoarthritis in 2 cases. There were also 2 cases of lumbar spondylodiscitis and 1 of finger clubbing in the series. The underlying heart disease was a valvular lesion of the left side of the heart in 10 cases out of 11 and the organism isolated by blood culture was a streptococcus in 9 cases and a staphylococcus in 11. We emphasis the need for early diagnosis and appropriate antibiotic therapy, in the absence of which the course may be fatal in the short term, as it was the case in one of our own patients.
Nouv Presse Med 1978 Dec
PMID:[Articular and muscular manifestations of bacterial endocarditis. 11 cases (author's transl)]. 74 39

The resaturation curve, a noninvasive indicator-dilution test using an ear oximeter to detect rates of change in arterial oxygen saturation during breathing of various concentrations of oxygen, was used to assess cardiac performance in normal subjects and in 108 patients with cardiac valvular disease. Measurements made during exercise included the time constant of resaturation (tau) and beat-to-beat changes in arterial oxygen saturation (the left heart clearance fraction). At maximum rates of voluntary work, patients had a significantly reduced clearance fraction and longer tau than normal subjects. Clearance fraction and tau improved in patients after aortic valve replacement; deterioration occurred in tau and clearance fraction over time in patients treated medically, as compared to normal subjects who showed little change during a ten-year period. Clearance fraction and tau correlated with hemodynamic data obtained during cardiac catheterization. The resaturation curve provides an objective measure of cardiac impairment that can be readily repeated during follow-up of patients with heart disease.
Chest 1976 Dec
PMID:Noninvasive measurement of cardiac function during exercise, using resaturation curves. 79 86

As part of the first examination conducted in the Paris Prospective Study, 6 565 healthy males aged between 42 and 53 years underwent a submaximal exercise test on the bicycle ergometer. Ischaemic changes in the ST segment during or after exercise were noted in 6% of the tests. The predictive value of these changes for the development of ischaemic heart disease after 4 years has been assessed. The risk of sequelae is 3.2 times greater in this group than in the group with no changes. The variations of this risk with the precise timing of the onset of these ischaemic ST segment changes during the course of the test and with the type of heart disease have been studied.
Arch Mal Coeur Vaiss 1976 Dec
PMID:[Prognostic value of ischemic changes of the electriccardiogram during and after exertion in an active male population]. 82 61

Infants born to mothers with disseminated lupus erythematosus occasionally have transient manifestations of the maternal disease. In six infants with congenital heart block born to mothers with systemic lupus erythematosus we postulated a causative relation. In one of the infants a post-mortem study of the conduction system suggested faulty embryonic development of the atrioventricular node with an abnormally thick annulus fibrosus and the effects of early inflammatory changes. Two of the infants had a cardiomyopathy and three, associated congenital heart disease.
N Engl J Med 1977 Dec 01
PMID:Association of maternal systemic lupus erythematosus with congenital complete heart block. 91 56


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