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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 78 consecutive patients with uniform ventricular ectopic complexes and without heart disease, ventricular couplets were present significantly more often when the coupling interval of ventricular ectopic complexes was variable than when it was fixed (P less than 0.04). In 69 consecutive patients with couplets, the prevalence of a variable coupling interval was significantly greater than that of (55 versus 14 cases; P less than 0.001). Among 55 patients with a variable coupling interval, ventricular parasystole was probable in 38 and possible in 17 patients. These results suggest that the association between ventricular couplets and parasystole is not coincidental. Of several possible mechanisms responsible for this association reentry within the parasystolic focus or its vicinity is the most probable. This may explain the observation that the couplets are seldom followed by consecutive ventricular ectopic complexes or ventricular tachycardia. If this hypothesis is correct, the clinical significance of ventricular couplets in the presence of ventricular parasystole may be similar to that of single reentrant ventricular ectopic complexes.
Am J Cardiol 1979 Sep
PMID:Coexistence of ventricular parasystole and ventricular couplets: mechanism and clinical significance. 47 22

Increasing attention is being given to radioisotopic studies of the right heart. Measurement of right ventricular ejection fraction has become more common. We present examples of cardiac images which were obtained during the scintigraphic assessment of right sided cardiac disorders. Images of the first pass, of the gated cardiac study, and of the nongated cardiac blood pools offer complementary information to the overall radionuclide evaluation of right heart disease.
Clin Nucl Med 1979 Sep
PMID:Abnormal images of right heart disorders. 47 64

An isochromosome for the long arm of chromosome number 18 - 46,XY,i(18q) - was found in an infant who had features of both trisomy 18 and 18p- syndromes. Findings compatible with trisomy 18 included postmature delivery, prominent occiput, severe congenital heart disease, overlapping fingers, and rocker-bottom feet. Those of 18p- syndrome, which frequently resembles Turner syndrome, were downward obliquity to the palpebral fissures, short, webbed neck, low posterior hairline, and widely-spaced nipples. The infant died of heart failure at 3.5 months of age. Parental karyotypes were normal.
Clin Genet 1979 Sep
PMID:Features of trisomy 18 and 18p- syndromes in an infant with 45,XY,i(18q). 48 37

A low-birth-weight infant with malformed upper extremities and congenital heart disease was observed. Cytogenetic analysis revealed a 46,XY,r(9)(p24q34) complement.
Hum Genet 1979 Sep
PMID:A ring chromosome 9 in an infant with malformations. 48 5

Glass and his colleagues have suggested that the type A coronary-prone behavior pattern, which is characterized by competitiveness, aggressiveness, and impatience, is a response style aimed at maintaining and asserting control over poentially uncontrollable events. The present investigation examined the initial reactions of type A and type B boys and men to uncontrollable events. Children and adults pressed a button to earn nickels on one of the following schedules of reinforcement: a variable ratio of 7 or a fixed ratio of 7. The variable ratio schedule was assumed to appear less controllable than the fixed ratio schedule. The task was either of high or low salience (prominence). Results replicated previous research that type A's initially respond to highly salient uncontrollable events with more vigorous efforts to assert control than type B's. More importantly, the findings provided the first evidence that (1) the initial response to loss of control of type A and type B boys parallels that of their adult counterparts; and (2) the boys' response to the salience of the task is similar to that of their adult counterparts. Implications of the children's responses to uncontrollable events for the maintenance of type A behavior into adulthood and for the etiology of heart disease are discussed.
Child Dev 1979 Sep
PMID:Efforts to control by children and adults with the type A coronary-prone behavior pattern. 49 57

The activated whole blood clotting time (ACT) was analyzed in vitro using blood samples from normal individuals and from patients with heart disease, scheduled for open heart surgery. The ACT was found to be normally distributed in a group of normal individuals with a mean of 135 sec. In patients with heart diseases, the average ACT was slightly shorter than in normal individuals. A linear relationship between ACT and heparin concentrations was established. Haemodilution and depletion of platelets did not significantly influence the ACT. When a clean venipuncture with disposable needles is used, ACT is a reliable, uncomplicated bedside technique by which heparinisation can be monitored.
Scand J Haematol 1979 Sep
PMID:Evaluation of the activated whole blood clotting time (ACT) in vitro. 50 72

To assess the relation of hyperaldosteronism and potassium depletion to the intensity of diuretic therapy we have measured plasma aldosterone by radioimmunoassay and total exchangeable potassium by radioisotope dilution in 24 patients when they were stable at the end of their preparation for cardiac operation. Some patients required intensive frusemide therapy to reach an optimal state for operation and many showed hyperaldosteronism. Plasma aldosterone was significantly related to daily dose of frusemide (r=0.77). Depletion of total exchangeable potassium expressed in terms of predicted weight was significantly related to plasma aldosterone (r= -0.64). The reduction in total exchangeable potassium is interpreted as chiefly related to loss of lean tissue mass from the wasting that leads to cardiac cachexia, but evidence is presented on the basis of measurements of extracellular fluid volume as sulphate space (20 patients) of entry of sodium into the cells which may indicate a true cellular potassium loss. Although plasma potassium is usually easily maintained with oral potassium supplements or aldosterone antagonists, we postulate that intensive diuretic therapy in severe heart disease may provoke hyperaldosteronism which accentuates potassium loss and may contribute to wasting and to intracellular potassium depletion in critical tissue, such as myocardium.
Br Heart J 1979 Sep
PMID:Relation of plasma aldosterone concentration to diuretic treatment in patients with severe heart disease. 50 54

Eighty-three patients whose atrial fibrillation appeared to be permanent and the sole cardiac abnormality at the time of diagnosis were followed for one to 19 years (mean 7.5 years). None suffered systemic embolism. Three died, none of cardiac disease. Sinus rhythm returned in seven. Another six developed features suggestive of other heart disease. In the remaining 67, the initial diagnosis of persistent lone atrial fibrillation remained tenable and they remained well.The medium-term prognosis for patients with this disorder seems good.
J R Coll Gen Pract 1979 Sep
PMID:Persistent lone atrial fibrillation--its prognosis after clinical diagnosis. 52 43

Simple and compound sagittally angled views of the heart obtained cineangiocardiographically with a parallelographic U-arm device were evaluated clinically in 132 patients with congenital heart disease. The principle advantage of the apparatus was the case with which axial and oblique projections were obtained without repositioning of the patient, although rotation and angulation of the image intensifier-X-ray tube unit resulted in some increase in scattered radiation. Certain angled views, particularly the 40 degree cranial and the compound 25 degrees cranial/70 degrees left oblique projections, were better than standard frontal and lateral views for visualization of pulmonary arteries in the mediastinum, in ventricular septal defects and anomalies of the left ventricular outflow tract.
Circulation 1977 Sep
PMID:Angled views in cineangiocardiography of congenital heart disease. 56 Feb 61

The blood hydrocortisone and corticosterone content and the aldosterone level in the urine were determined for 24 hours in patients with congenital heart disease before and after operative treatment. In patients with symptoms of cardiac insufficiency both glucocorticoid and mineralocorticoid activity of the adrenal cortex was marked by deviations from the diurnal physiological rhythm. This is reflected in the continuous activation of the adrenal cortex during 24 hours; activation of mineralocorticoid function in the evening and during the night is a particularly characteristic phenomenon.
Kardiologiia 1977 Sep
PMID:[Diurnal rhythm of the adrenal cortex function in patients with circulatory disorders]. 56 52


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