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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Intracellular microelectrodes were used to study the electrophysiological effects on action and resting potentials, refractory periods and conduction velocities of four contrast media administered either as 1/100 and 1/1000 solutions or as 20 mg bolus injections. The products studied were Telebrix, which has high osmolality (2100 mOsm/kg) and three other contrast media with lower osmolatity (700 mOsm/kg), including Hexabrix, which contains sodium, and Iopamidol and Iohexol which are sodium-free. The parameters measured were not modified by Hexabrix and Telebrix, whereas Omnipaque and Iopamiron induced varied and significant changes in these parameters, notably in concentrations of 1/100 and as bolus injections. It is suggested that the latter contrast media should be used in non-cardiovascular explorations and in patients without confirmed heart disease.
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PMID:[Intracellular microelectrode study of the electrophysiological effects of contrast media]. 314 53