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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Having observed 18 cases, the authors describe a syndrome of recurrent paroxysmal atrial arrhythmia which was very homogeneous from the clinical and ECG point of view. It was usually found in middle aged males, with no demonstrable underlying heart disease, whose disorder of intra-atrial conduction occurred during sinus rhythm. The condition developed slowly over the course of years towards a maximum incidence of several short daily attacks of an arrhythmia which alternated between an atrial fibrillation and atrial flutter. Vagal overactivity is the precipitating cause of these attacks which are usually not completely nocturnal. The condition never progressed to sino-atrial block nor to permanent fibrillation. The beginning of each attack, often heralded by atrial coupling with a long enough interval to cause re-entry, is accompanied by slowing of the sinus rate down to the threshold level. The vagal effect of shortening the action potential and refractory period is recognised to be non-homogeneous in the atrial wall, and suggests a re-entry mechanism rather than hyper-excitability. This would explain the usual resistance of atrial arrhythmias of vagal origin to digitalis, beta blockers and quinidine. Amiodarone alone is usually effective because of the prolongation of the action potential which it causes. In 5 particularly resistant cases a good clinical result was obtained by the insertion of an atrial pacemaker with a fairly rapid rate.
Arch Mal Coeur Vaiss 1978 Jun
PMID:[The atrial arrhythmia syndrome of vagal origin]. 2 9

The authors present their experience of heart disease in children with congenital abnormalities of alcoholic origin, of which they have seen 50 cases in 3 years. This syndrome, which was first described by Lemoine in 1968, appears to be fairly common. It shows the teratogenic properties of alcohol. It is characterised by facial abnormalities which are easy to recognise, gross failure to gain in height and weight, psychomotor retardation of varying severity and several other malformations. From amongst these, cardiac malformations are the most commonly encountered. These are usually in the form of septal defects (atrial and ventricular septal defects).
Arch Mal Coeur Vaiss 1978 May
PMID:[The heart diseases of children born to alcoholic mothers]. 7 93

Over the course of 17 years, 7 women have had heart disease either during the last three months of pregnancy or during the first three months post-partum, which appear to be associated with their pregnancy. Enquiries made throughout the country and relating to the last decade have yielded 11 additional cases so far unpublished. The clinical features of these cases do not differ from those of other non-obstructive cardiomyopathies occurring other than in pregnancy. The prognosis depends essentially on the factor of cardiac volume during the first few months of the disorder: if significant cardiomegaly persists, death will follow in one case out of two. There exists the problem of the criteria for making a diagnosis of myocardial disease of pregnancy. It should be emphasised that only 4 of the 18 cases were different from the usual cases of myocardial disease, in that they progressed to recovery which is unusual in this condition. One case was particularly illustrative of this, as clinical cure was followed by a relapse at subsequent pregnancy. Because the pregnancy itself seems to be the cause in such a tiny number of cases, a new hypothesis seems right; this is that pregnancy does no more than aggravate an associated or already existent myocardial disorder.
Arch Mal Coeur Vaiss 1978 Apr
PMID:[Myocardiopathy of pregnancy in white women]. 9 59

The authors report two cases of infants with complex heart disease comprising transposition of the great vessels, and a major unilateral facial anomaly involving the ear and the mandible, conforming to the description of hemifacial microsomia. The facial anomalies seen are defined and placed in the classification of known syndromes. The incidence of heart disease associated with facial microsomia is about 20% and in 2/3 of cases it is a ventricular septal defect or a tetralogy of Fallot. An analysis of aetiological factors shows that syndromes of the first two branchial arches are usually sporadic and that they may be the result of intra-uterine disease. The mechanism of the facial lesions is probably vascular.
Arch Mal Coeur Vaiss 1978 Oct
PMID:[Hemifacial microsomia and cardiac malformations. Apropos of 2 cases]. 10 88

132 patients with pure mono-valvular cardiopathies (mitral incompetence, aortic stenosis and aortic incompetence) were classified into two groups according to the values of the systolic work index/myocardial mass ratio (SWI/MLV). Normal values of the ejection function (EF) and mean velocity of circumferential fibre shortening (VCF) for each cardiopathy were so obtained. Only patients with aortic stenosis of group I (SWI/MLV greater than or equal to 0.75 gm . g-1) had normal EF. All the other patients had EF and VCF values below normal although this did not always imply impaired myocardial function. Therefore the myocardial mass should also be considered in the evaluation of myocardial function and it would seem desirable to take this parameter into account in the management of these patients.
Arch Mal Coeur Vaiss 1978 Dec
PMID:[Indices of left venticular performance and evaluation myocardial quality in mitral valve insufficiency, chronic aortic valve insufficiency and stenosis]. 10 91

Right-sided aortic arch with a retro-oesophageal segment is much rarer than right-sided aortic arch without a retro-oesophageal segment. As opposed to the latter situation which is always associated with congenital heart disease, it is usually an isolated finding. The left subclavian artery arises from a posterior diverticulum and may be stenosed at its origin, giving rise to a systolic murmur as in one of the reported cases, or to a subclavian steal syndrome. The ligamentum arteriosum completes the aortic ring and may give rise to respiratory problems at varying ages and of variable severity, sometimes attributed to asthma. In one of the cases followed up over 15 years chronic respiratory problems and late tracheal lesions were observed. Although the possibility of a double aortic arch may be raised, early surgical treatment is desirable.
Arch Mal Coeur Vaiss 1979 May
PMID:[Right aortic arch with retro-esophageal component. 2 cases]. 11 10

Report of the case of a 50-year woman with a cyanotoc congential heart disease, relatively well tolerated up to the age of 49. The diagnosis was made at autopsy only. No case published in the literature till now had exceeded the age of 45 years, although the types of truncus arteriosus.
Arch Mal Coeur Vaiss 1975 Jun
PMID:[Type IV truncus arteriousus in a 50-year-old woman]. 12 71

The authors have followed up children with cardiac defects over almost a twenty year period. During the 1960's most of their patients had come of age, and they conclude that despite the enthusiasm of these young people and their potential, they have the greatest difficulties in finding work. This seems regrettable from the human as well as the socio-economic point of view. They propose that the law should be changed as, indeed, should the spirit of the law, so that; a subject with heart disease should no longer be considered as incapable of useful work, and that each person should be assessed according to his potential. They envisage the setting up of medico-administrative cardiological centres. Thus, in addition to the purely medical cardiological consultation, three additional persons would add their expertise: a social worker, an industrial medicine inspector, and an employment officer. These centres could be instituted easily, without making the existing system too unworkable.
Arch Mal Coeur Vaiss 1976 Jun
PMID:[Problems posed by professional rehabilitation of cardiac patients]. 13 48

The authors report a case of carcinoid heart disease secondary to a tumour of the small bowel with liver metastases. There were severe lesions of the endocardium on the right side of the heart, with gross pulmonary and tricuspid incompetence. The left side of the heart did not escape but the fibrous plaques were limited to the papillary muscle of the mitral valve, and had no effect upon the haemodynamics. The pathogenesis of the strange cardiac lesion may be partly explained in terms of the toxicity to the endothelium of bradykinin. In spite of the serious nature of the valvular damage is it right to consider surgical correction, bearing in mind the fact that the prognosis of carcinoid syndrome is still very poor despite treatment?
Arch Mal Coeur Vaiss 1977 Nov
PMID:[Carcinoid heart disease secondary to a tumor of the small intestine. Apropos of a case with associated tricuspid and pulmonary insufficiency]. 14 56

The authors report the study of 259 cases of congenital heart disease observed at Abidjan between 1969-1976. The average age of the patients was 7-8 years ranging from the newborn to 41 years. The principal malformations encountered in their order of frequency were: ventricular septal defect 38.6 p. 100, atrial septal defect 13.8 p. 100, Fallot's tetralogy 8.8 p. 100, pulmonary stenosis 8.1 100, patent ductus arteriosus 7.7 p. 100, atrioventricular canal 7.7 p. 100, transposition of the great arteries 3.8 p. 100, coarctation of the aorta 2.3 p. 100. There were associated malformations in 31 cases. 42 patients were catheterised at Abidjan, 28 were operated, 12 at Abidjan. These statistics are compared to those already reported of congenital heart disease in tropical and western countries. There is little difference in the distribution of the various cardiac malformations. Two congenital malformations appear to be less frequent in the Tropics: coarctation of the aorta and aortic stenosis.
Arch Mal Coeur Vaiss 1979 Mar
PMID:[Congenital cardiopathies in a tropical environment. Study of 259 cases seen at Abidjan from 1969-1976]. 22 23


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