Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 25 patients with angiographically proven coronary heart disease and in 15 patients without heart disease, gated cardiac blood pool scintigraphy was done with 15 mCi 99mTc-HSA in LAO projection. Scintigraphic data were collected in list mode by means of a gamma camera connected to a computer system (Siemens 330). A cumulative scintigram scintigram sequence with a time resolution of 100, 50 and 25 frames/sec was constructed using several hundred heart cycles of equal duration. After background correction volume curves of the left ventricle with a time resolution of 25, 50 and 100 Hz were obtained and the following parameters of these curves were compaired: ejection fraction, maximum ejection rate and maximum filling rate. It could be demonstrated that smoothing by sliding average requires a time resolution of at least 50 Hz, whereas in volume curves smoothed by Fourier-Analysis a time resolution of only 25 Hz is necessary. However, using a time resolution of 25 Hz, the course of the volume curve can not always be clearly demonstrated, so that time resolution of 50 Hz combined with Fourier-Analysis for the gated cardiac blood pool scintigraphy is preferred.
 ...
PMID:[Time resolution of scintigraphically determined left ventricular volume curves (author's transl)]. 53 Aug 43