Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The peripheral arterial occlusive disease (PAOD) of the lower extremities caused by atherosclerosis is usually associated with the one in the coronary and cerebral arteries. Life expectancy of patients having PAOD is shorter for about 10 years and most of these patients die from a heart disease or insult. Arterial occlusive Such a multi-segment disease is also associated with the poorer general cardiovascular health condition and higher morbidity and mortality than in the case of a localized one-segment disease. Numerous studies have shown that the etiology of a disease in the changes in the legs usually develop at several levels within the arteries, but it is possible to localize them only in one limited region in the vessel. When stenosis is found on several places, the blood flow in the lower extremities is often very compromised, and ischaemia of the legs may become an important clinical problem. lower extremities may vary depending on the anatomic site of me lesion. Aorto-iliac disease seems to develop in younger patients who smoke, whereas a more distal lesion in the infrapopliteal arteries is primarily found in diabetic patients.
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PMID:[Anatomic distribution of peripheral atherosclerosis and its correlation with lipid disorders]. 1970 21