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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

"Cardiomyopathy", a term formerly used for heart muscle disease of unknown aetiology, is at present applied to all myocardial diseases other than coronary-heart disease. This definition includes many different forms of metabolic disorders of heart muscle. Four manifestations of metabolic myocardial disease, differing in their aetiology and pathogenesis are distinguished: (1) "transport" myocardosis, (2) "arthrocytotic" myocardosis, (3) myocardia, and (4) idiopathic cardiomyopathy. They are differentiated by combined morphological and quantitative mineral examination. "Transport" myocardosis is the most common form and its particular aetiology can be further specified. Cause of death in patients with metabolic disorders often remains undiscovered even at autopsy. Combination of histological and quantitative mineral analysis of myocardium can further define the particular form.
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PMID:[Myocardosis - myocardia - cardiomyopathy (author's transl)]. 94 24

Changes of the mineral concentrations of the heart muscle can point at disturbances of myocardial metabolism. Disturbances of heart muscle with functional loss and without coronary or inflammatory heart disease are called myocardosis, especially cardioplegic myocardosis after open-heart surgery with extracorporal bypass. 30 dogs were examined in three groups varying the method of induced cardiac arrest: 1. ischemic cardiac arrest by clamping the ascending aorta, 2. functional cardiac arrest by electrically induced fibrillation and 3. ischemic cardiac arrest and in addition injection of a Mg-aspartate-procain-solution. Sodium, potassium, magnesium, calcium, copper and zinc were analyzed by atomic absorption spectrophotometry. Specimens from the left and right ventricular wall were examined before and after extracorporal circulation. After a recovery period for one hour the dogs were killed and specimens from the right and left ventricular wall and from the basis and apex of the interventricular septum were taken and reduced to ashes with mineral acids. In all animals changes of the mineral content were most marked after the recovery period. In all forms of cardiac arrest mineral metabolism showed monotone reactions: water content increased, potassium and magnesium decreased. Variations of mineral concentrations were more expressed in the right ventricular wall than in the left. Animals with cardiac arrest by electrically induced fibrillation indicated the smallest deviations from the basic values. The comparison of the values of dogs with sufficient circulation at the end of the experiments and those dogs with medicamentally or mechanically supported circulation at this time showed a more increased water content and simultaneously a decrease of all cations in the group with supported circulation. The decrease of the osmolality of the cations seems to be the metabolic answer to the increased cardioplegic damage of heart muscle.
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PMID:[Myocardial electrolytes in "cardioplegic" myocardosis (author's transl)]. 122 Jun 68

The cardiovascular effects of the ingestion of ethyl alcohol are determined by the amount consumed and time factors as well as the nutritional status of the individual. Acute alcoholism produces various cardiac manifestations that are related primarily to the concentration of alcohol in the blood. Chronic alcoholism is associated with three identifiable cardiovascular syndromes that have been designated alcoholic myocardosis, nutritional heart disease and beriberi heart disease. Differentiation is indicated because of their respective distinguishing diagnostic features and prognostic implications. The therapeutic effects of alcohol in coronary artery disease are apparently attributable to cerebral responses rather than demonstrable increase in coronary blood flow.
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PMID:The heart and alcohol. 1330 84