Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Infective endocarditis (IE) is a lethal complication inpatients with congenital heart disease. We report a case of percutaneous implanted pulmonary valve IE in a 49-year-old female. She underwent a previous surgery for tetralogy of Fallot with transannular patching of the right ventricular outflow tractat the age of 18 years. Echocardiography showed chronic moderate to severe pulmonary regurgitation with right heart enlargement. She underwent transcatheter pulmonary valve implantation with a 26 mm Venus-P valve (Venus Medtech, Shanghai, China) in order to release pulmonary insufficiency. Two months after implantation, she presented with recurrent chills and febrile for one week, and percutaneous implanted pulmonary valve IE was diagnosed. According to the antibiotic susceptibility test, she was given penicillin and gentamycin. At 12 months follow-up, TTE showed vegetation completely disappeared and the valve functioned normally. The patient recovered uneventfully without any complications like recurrent IE.
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PMID:Infective Endocarditis in a Patient with Transcatheter Pulmonary Valve Implantation. 3125 31

Almost 90% of children with congenital heart disease now reach adulthood due to the improved results of cardiac surgery and medical treatment. Among them, one of particular problems is pulmonary valve regurgitation after tetralogy of Fallot repair. About 20 years ago (1996), the mortality of tetralogy of Fallot has already been relatively good at about 5%, but now it is further reduced to about 2%. For this reason, it is conceivable that more and more adult patients with tetralogy of Fallot will increase in the future. Pulmonary valve regurgitation is often caused by the use of transannular patch repair. Surgical indications for pulmonary valve regurgitation include those with decreased exercise tolerance, right ventricular dysfunction, advanced right ventricular enlargement. We examined treatment strategies, valve selection and catheter valve implantation.
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PMID:[Surgical Management of the Patients with Tetralogy of Fallot; Long-term after Initial Repair]. 3126 10

Patients with congenital heart disease that involves reconstruction of the right ventricular outflow tract must frequently undergo interventions derived from the limited useful life of the surgical canals, which leads to the development of right ventricular dysfunction due to changes in the ventricular geometry and predisposition to lethal arrhythmias, with the consequent risk of reinterventions. The percutaneous pulmonary valvular implant is a new therapeutic alternative, less invasive, compared to surgery, for selected patients. A review of the available literature is made and the initial experience of percutaneous pulmonary valve implantation in a Colombian center of high complexity for the treatment of cardiovascular diseases is described, in two patients with aortic homograft dysfunction in a pulmonary position with double valvular lesion, in which the percutaneous pulmonary valve implant was a successful strategy. Patients with congenital heart disease were chosen, with dysfunctional surgical conduits with stenosis or significant pulmonary insufficiency, with dysfunction and right ventricular dilatation. The standard technique for the implantation of the Melody pulmonary valve was used, without complications during the procedure or one year of follow-up. Percutaneous implantation of the pulmonary valve is a great advance in the management of patients with congenital heart diseases, with favorable results in the short and medium term, allowing the restoration of ventricular function with minimal risk, compared to surgical replacement in selected patients.
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PMID:Percutaneous pulmonary valve implant: Two Colombian case reports. 3295 60


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