Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hereditary palmoplantar keratoderma (1) has been found to be associated with syndromes such as corneal defects, (2) periodontosis, carcinoma of esophagus but not so much with congenital heart disease. A case of Tylosis with pulmonary stenosis is reported. Very many hereditary disorders characterised by diffuse or focal thickening of the palms and soles have been described. Tylosis is determined by an autosomal dominant gene and presents with slight thickening of palms and soles first evident in early infancy and fully described by the sixth month. There have been no congenital anomalies associated with tylosis in the literature.
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PMID:Congenital heart disease in tylosis: case report. 178 10