Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018799 (heart disease)
 34,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Anti-heart antibodies detected by indirect immunofluorescence were found in the blood of persons deceased suddenly of heart failure more often (36,7%) than in those who died of other causes (16,6%). Antibodies were found the most frequently in rheumatic heart failure (50%), in other heart diseases (50%), and in ischemic heart disease (35,5%). In ischemic heart disease there was a high level of antibodies in patients with chronic heart aneurysm (66,6%) as compared with low level in those with acute infarction (16,6%). Obviously, antiheart antibodies often accompany a heart disease without being closely related to the heart failure. A negative result of serological examination does not exclude a heart disease.
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PMID:[Heart antibodies in sudden death]. 712 44

Specific features of acute myocardial infarction (AMI) onset and course, short-term outcome and its causative factors have been analysed for women and men by the data from Register of Acute Myocardial Infarction of the city of Tomsk for 1994-1998 (a total of 3717 cases). It is shown that AMI men die largely of cardiogenic shock (CS), congestive heart disease (CHD) and cardiac arrhythmia. Death of AMI women was caused primarily by CS, CHD and rupture of the myocardium. For women the unfavourable factors for an AMI outcome were the following: an atypical clinical presentation, a symptomless preinfarction period, prior AMI, arterial hypertension, diabetes mellitus, a complicated course, extensive and transmural lesion, acute cardiac aneurysm. For men the additional to these are previous angina and brain stroke. The short-term AMI outcome in women is more unfavourable than in men.
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PMID:[Acute myocardial infarction onset, course and short-term outcome in men and women]. 1181 Nov 3

The aim of the work was to identify risk factors of atrial fibrillation (AF) in 151 patients with metabolic syndrome (MS, IDF 2005); 88 of them presented with the recurrent form of AE 63 had no arrhythmia. Practically all patients suffered from arterial hypertension. The groups were comparable in terms of age, concomitant disorders, AH duration, arterial pressure, and severity of chronic heart failure. Patients with permanent AF, hemodynamically significant heart disease, myocardial infarction with wave Q in the medical history, and cardiac aneurysm were excluded from the study. We evaluated anthropometric parameters, carbohydrate and lipid metabolism, daily albuminuria, results of echoCG, and insulin resistance. Patients with AF had worse anthropometric and metabolic parameters and more pronounced remodeling of myocardium with left ventricular diastolic dysfunction, insulin resistance, endothelial dysfunction, and renal lesions than patients with MS without AF Patients with MS having abdominal obesity and AH over 10 years, marked insulin resistance (IR index higher than 2.77), reduced HDL cholesterol level (below 1.1 mmol/l), left atrial dilation (end diastolic size >43mm), albuminuria >60 mg/d, waist circumference >104 cm were at high risk of AF (prognostically unfavourable arrhythmia). It is concluded that dynamic observation of the above MS and echo-CG parameters, and albuminuria coupled to the adequate correction of insulin resistance, control of AH and dyslipidemia is important for the prevention of cardiac arrhythmia.
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PMID:[Assessment of risk factors of atrial fibrillation in patients with metabolic syndrome]. 2256 46