Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 3810
MRI 2611
She 2032
CSF 899
calcitonin 397
Pol 292
prolactin 292
calcium channel 206
hemoglobin 199
interferon 166
insulin 164
C-reactive protein 163
growth hormone 158
cytokine 155
CD4 141
Mol 139
SARS 139
glial fibrillary acidic protein 137
olfactory 136
5-hydroxytryptamine 131
phosphodiesterase 130
hole 123
substance P 121
renin 109
tap 104
ENT 98
ACTH 95
collagen 93
reserved 93
beta-endorphin 89
vasopressin 87
panhypopituitarism 81
somatostatin 81
tumor necrosis factor 81
cytochrome P450 79
5-HT1B 79
vimentin 78
CGRP 72
CRP 72
Gen 72
ESR 72
neurofibromatosis 71
synaptophysin 71
Calcitonin 70
albumin 69
CO2 68
IgE 68
IL-6 67
axonal 66
alkaline phosphatase 65
FDG 64
TNF 63
IFN 63
ASA 63
fibrinogen 62
chronic renal failure 62
prothrombin 62
alanine aminotransferase 61
MIB 60
GABA 60
FSH 58
CACNA1A 58
Ki-67 58
gut 57
JAMA 57
lymphoid 57
IgA 56
PRL 56
nitric oxide synthase 56
Pseudomonas 53
mast cell 53
ACE 53
ANOVA 52
ICD 51
trip 50
Mil 49
San 49
cyclooxygenase 48
HT3 47
CD34 47
Men 47
HLA 47
white cell 47
interleukin-6 46
ferritin 46
Golgi protein 46
erythropoietin 45
aspartate aminotransferase 44
serotonin receptor 44
CD8 44
lactate dehydrogenase 44
vascular endothelial growth factor 44
5-HT3 receptor 42
Mal 42
strabismus 41
glycoprotein 41
Polymerase 39
ATP 39
asymmetrical 39
granulocyte colony-stimulating factor 38
S100 38
p53 38
5-HT1D 38
Hop 38
ATP1A2 38
granulocyte 38
HDL 38
thyroid hormone 37
REM 37
SBP 36
orexin 36
adrenocorticotropic hormone 36
creatine kinase 36
CYP3A4 36
angiotensin II 36
chorionic gonadotropin 36
protein S 36
interleukin-2 36
CD20 36
non-Hodgkin's lymphoma 35
VIII 35
bradykinin 35
protease inhibitor 34
all-trans 34
polypeptide 34
ADP 34
rheumatoid factor 33
myeloperoxidase 33
cytokeratin 33
thromboplastin 33
tyrosine kinase 33
DBP 33
TMD 33
CAT 33
LHRH 33
GCS 33
CGI 32
BID 32
LDH 32
lipopolysaccharide 32
IL-1 32
CCM1 31
nodal 30
neurofibromatosis type 1 30
interferon-alpha 30
antithrombin III 30
thrombin 29
anonymous 29
ES2 29
c-fos 29
cyclooxygenase-2 29
TNF-alpha 29
COX-2 29
BRAF 29
NMDA receptor 28
NMR 28
T12 28
IMP 28
acetylcholinesterase 28
CCM2 28
more...
Disease
migraine 8998
tumor 3033
hypertension 2890
depression 2124
stroke 1948
cancer 1381
subarachnoid hemorrhage 1154
meningitis 1089
rash 1044
epilepsy 986
hydrocephalus 983
diplopia 946
hemiparesis 860
confusion 816
encephalopathy 800
chronic pain 710
coma 655
vasculitis 606
encephalitis 559
diabetes 541
thrombocytopenia 530
tension headache 516
fits 509
meningioma 492
HIV 483
Horton 468
influenza 449
anemia 443
sinusitis 442
metastases 442
asthma 423
giant cell arteritis 413
Headache Disorders 401
pruritus 391
systemic lupus erythematosus 381
infectious diseases 375
cold 364
pituitary adenoma 357
pneumonia 354
multiple sclerosis 334
blindness 334
fibromyalgia 331
pheochromocytoma 328
AIDS 321
trigeminal neuralgia 319
ischemia 309
obesity 303
prolapse 301
brain tumor 299
neuropathy 298
carcinoma 291
lymphadenopathy 289
arthritis 284
meningoencephalitis 279
lymphoma 278
dementia 278
tuberculosis 271
Posterior 270
cognitive impairment 268
malaria 265
amenorrhea 265
aseptic meningitis 259
dengue 259
virus infection 253
arteriovenous malformation 251
common migraine 243
meninges 232
immunodeficiency 228
xerostomia 225
aphasia 225
nystagmus 224
hypopituitarism 223
diabetes insipidus 223
Pseudotumor cerebri 220
glioma 214
major depressive disorder 214
proptosis 211
sleep disturbances 210
sleep disorders 209
preeclampsia 209
dyspepsia 208
eclampsia 208
cerebral infarction 207
rheumatoid arthritis 207
psychosis 207
adenoma 205
schwannoma 205
adenocarcinoma 203
raised intracranial pressure 202
hemiplegic migraine 200
breast cancer 200
heart failure 199
renal failure 199
dysphagia 198
brain abscess 194
astrocytoma 194
essential hypertension 193
West 188
myocardial infarction 187
lupus 185
Pituitary 183
hemangioma 182
bacterial meningitis 182
SARS 180
hallucinations 180
vascular disease 176
facial palsy 173
disorientation 172
transient ischemic attack 170
proteinuria 170
leukopenia 169
neutropenia 168
rhinitis 166
claudication 165
leukemia 165
sepsis 163
anxiety disorders 162
Cryptococcus neoformans 160
rare disease 160
mental illness 158
leukoencephalopathy 156
pachymeningitis 156
acne 153
neurological disease 153
vascular headache 151
abortion 149
cryptococcal meningitis 149
Horner's syndrome 148
renal disease 146
melanoma 146
moyamoya 145
Infection 144
sepsis 143
hypothyroidism 140
craniopharyngioma 140
peripheral neuropathy 140
pituitary tumor 139
hepatitis 138
mountain sickness 135
scotoma 135
osteoarthritis 134
menstrual migraine 134
hyperprolactinemia 134
lupus 134
cerebral ischemia 133
urticaria 133
herpes simplex 131
conjunctivitis 128
irritable bowel syndrome 128
sleep apnea 127
paraganglioma 127
fungal infection 127
coronary artery disease 127
pneumocephalus 127
cardiovascular disease 125
incontinence 124
galactorrhea 124
dysplasia 123
pulmonary edema 122
heart disease 121
more...
Symptom
headache 56091
pain 10057
nausea 4831
vomiting 4132
dizziness 2924
seizures 2841
fatigue 2476
diarrhea 1434
weakness 1325
myalgia 1148
abdominal pain 1142
cough 1050
sleepiness 1010
vertigo 998
anesthesia 948
facial pain 858
nausea and vomiting 800
insomnia 779
arthralgia 719
back pain 703
Ill 694
ataxia 679
neck pain 661
chills 567
flushing 567
photophobia 554
anorexia 538
tinnitus 536
dyspnea 520
blurred vision 485
discomfort 471
discomfort 456
numbness 441
analgesia 440
paresthesia 431
constipation 416
chest pain 387
lethargy 352
sore throat 334
tremor 329
agitation 318
asthenia 311
neck stiffness 310
rhinorrhea 303
paresis 297
ophthalmoplegia 289
angina 272
low back pain 259
syncope 256
dysarthria 245
neuralgia 237
hemiplegia 231
erythema 225
nasal congestion 210
shortness of breath 169
anosmia 155
meningism 154
otalgia 149
spasm 142
pallor 129
memory loss 126
consciousness disturbance 114
lightheadedness 113
nasal discharge 113
orofacial pain 112
dystonia 107
sneezing 105
acute pain 105
snoring 105
overweight 104
dental pain 102
eye pain 102
polyuria 100
tingling 99
respiratory distress 98
ENT 98
tonic-clonic seizure 97
splenomegaly 95
cerebellar ataxia 91
cancer pain 91
decreased appetite 89
bone pain 88
hepatomegaly 86
collapse 86
hot flushes 86
abdominal discomfort 85
Hemicrania 83
shoulder pain 83
stomach pain 79
spasticity 77
rigors 77
hoarseness 73
polydipsia 72
epigastric pain 72
pelvic pain 68
hepatosplenomegaly 67
paraparesis 66
night sweats 64
myoclonus 63
bloating 62
leg pain 61
cyanosis 60
abdominal cramps 60
fever of unknown origin 59
excessive sweating 59
hemoptysis 59
giddiness 59
giddiness 59
muscle cramps 54
chest tightness 51
forgetfulness 50
wheezing 49
limb pain 49
lassitude 48
throat irritation 48
hypercapnia 48
oliguria 46
ataxic gait 46
enuresis 45
exhaustion 45
mastalgia 45
apathy 44
loss of taste 44
Wind 44
heartburn 43
dysesthesia 43
chorea 42
jaw pain 40
irregular bleeding 40
hot flashes 38
hangover 38
body pain 37
postnasal drip 36
hypothermia 36
torticollis 34
menopausal symptoms 33
arm pain 32
dysuria 32
thinning 32
tachypnea 31
colic 30
Tenderness 30
hypersomnia 29
generalized pain 28
dry skin 28
distraction 28
partial seizure 27
dry eye 27
Thunderclap headache 26
hunger 26
Kernig's sign 25
incoordination 25
sinus headache 24
rales 24
prostration 24
functional recovery 24
personality change 23
hypertonia 23
hypotonia 22
skin irritation 22
more...
Drug
CSF 910
caffeine 309
nitroglycerin 228
Cardiovasc 189
Dermatol 177
ENT 141
Norplant 108
ampicillin 83
EE2 71
Norplant 68
Indomethacin 57
Asthma 53
Almotriptan 42
MAP 41
Histamine 39
Rizatriptan 39
Metrizamide 38
Monit 34
Spectrum 31
Leaf 29
Dihydroergotamine 29
Levonorgestrel 28
lysine 28
Prednisolone 28
Viagra 27
G-CSF 27
Photofrin 26
CTA 25
Botox 24
Doxycycline 24
Eletriptan 24
Depo-Provera 24
Triad 23
Tacrolimus 23
CTX 23
Viagra 23
IL-2 22
Ranitidine 21
Modafinil 20
Iohexol 20
Felodipine 20
Gabapentin 20
Portal 19
Cilostazol 19
Fluconazole 19
Nephron 19
Zomig 19
Almotriptan 19
HCG 19
Methylprednisolone 18
Domperidone 17
Vardenafil 17
Bevacizumab 17
CIA 16
Fluorescein 16
Infliximab 16
Infliximab 16
Dial 16
Isradipine 16
Frontal 16
Nephron 15
Dakar 15
Iloprost 15
Spectrum 15
CFS 15
Fluorescein 14
PTH 14
Growth hormone 14
Prednisone 14
DDAVP 14
Xanthium 14
Acyclovir 14
Clonidine 14
lactose 14
DDAVP 14
Rituximab 14
BOTOX 14
IFN-gamma 14
ascorbate 14
Frovatriptan 13
DPA 13
vitamin E 13
Sumatriptan succinate 13
Duloxetine 12
Sumatran 12
Growth hormone 12
OTC 11
Iopamidol 11
Enprofylline 11
Pregabalin 11
AZT 11
Coral 11
Check 11
BoNT/A 11
Sandostatin 11
Tianma 11
OTC 11
Theophylline 11
Sandostatin 11
AZT 11
ACT 10
Bayer 10
Diphenhydramine 10
Imatinib 10
Zonisamide 10
Anagrelide 10
Sodium valproate 10
niacin 10
Ketoconazole 9
DBS 9
Roflumilast 9
Alliance 9
AmBisome 9
Camp 9
Treprostinil 9
Pizotifen 9
Phenytoin 9
Atenolol 9
Clopidogrel 9
Roflumilast 9
Escitalopram 9
Moclobemide 8
Estrogens 8
Amoxicillin 8
ADR 8
Navoban 8
TAC 8
Azithromycin 8
Ketorolac 8
PCB 8
Navoban 8
Conray 8
Mirtazapine 8
Butalbital 7
uPA 7
ROC 7
Valsartan 7
Rufinamide 7
MgSO4 7
TMS 7
Naproxen sodium 7
Cimetidine 7
Cimetidine 7
Ofloxacin 7
Omeprazole 7
Itraconazole 7
Levosimendan 7
Fulvestrant 7
Fentanyl 7
Aliskiren 7
Encore 7
IFN-beta 7
Omalizumab 7
Riboflavin 7
Molsidomine 6
Coumadin 6
Biltricide 6
THF 6
Triad 6
Tegaserod 6
more...
Enzyme
phosphodiesterase 130
alanine aminotransferase 118
renin 109
ERK 108
ACE 102
aspartate aminotransferase 73
monoamine oxidase 67
creatine kinase 66
alkaline phosphatase 65
acetylcholinesterase 62
lactate dehydrogenase 57
focal adhesion kinase 52
peroxidase 49
reverse transcriptase 48
cholinesterase 47
catalase 47
mitogen-activated protein kinase 45
CYP3A4 36
APC 36
thromboplastin 35
botulinum neurotoxin 30
gamma-glutamyl transpeptidase 30
thrombin 29
AST 26
adenylate cyclase 25
superoxide dismutase 25
carbonic anhydrase 23
calcineurin 23
ATPase 21
NO synthase 20
PDE 18
methylenetetrahydrofolate reductase 18
tissue plasminogen activator 18
methylenetetrahydrofolate reductase 18
asparaginase 17
enolase 15
RNA polymerase 15
aldehyde dehydrogenase 15
urokinase-type plasminogen activator 15
beta-lactamase 14
succinate dehydrogenase 14
trypsin 14
alcohol dehydrogenase 14
guanylate cyclase 14
CD10 13
lipase 13
adenosine deaminase 12
NOS 12
adenosine deaminase 12
protein kinase 12
ornithine transcarbamylase 12
glutathione peroxidase 11
P-glycoprotein 11
GCA 11
proteasome 11
transcriptase 11
thyroid peroxidase 10
plasmin 10
diamine oxidase 10
caspase-1 10
CAD 9
angiotensin-converting enzyme 2 9
CAD 9
neuraminidase 9
lysozyme 9
CAD 9
ADH 9
BMT 8
protein kinase C 8
indoleamine 2,3-dioxygenase 8
aldehyde dehydrogenase 8
caspase-3 8
ACS 8
MEK 8
PARP 7
tryptophan hydroxylase 7
MDP 7
tryptase 7
DNA polymerase 7
aldehyde dehydrogenase 6
topoisomerase 6
aldehyde dehydrogenase 6
aldehyde dehydrogenase 6
luciferase 6
xanthine oxidase 6
alpha-galactosidase 6
MTD 6
prostate-specific antigen 6
topoisomerase 6
complex I 5
urease 5
AOR 5
CDH 5
kallikrein 5
CD13 5
BAL 5
3-hydroxy-3-methylglutaryl coenzyme A reductase 5
cytochrome oxidase 5
transglutaminase 5
PTA 5
ceruloplasmin 5
isocitrate dehydrogenase 5
isocitrate dehydrogenase 5
glutathione S-transferase 5
urease 5
GABA transaminase 5
21-hydroxylase 5
UDP-glucuronosyltransferase 4
MAP 4
ECH 4
PCP 4
tyrosine hydroxylase 4
MIP 4
PMT 4
BMA 4
citrate synthase 4
monoacylglycerol lipase 4
MAT 4
CPT 4
MAT 4
CPT 4
CPT 4
endonuclease 4
lactase 4
HSD 3
acid phosphatase 3
NADPH oxidase 3
choline acetyltransferase 3
PAM 3
beta-glucuronidase 3
glutaryl-CoA dehydrogenase 3
paraoxonase 3
dopamine beta-hydroxylase 3
phenylalanine hydroxylase 3
NADPH-diaphorase 3
VOR 3
elastase 3
neutrophil elastase 3
phospholipase A2 3
histidine decarboxylase 3
glutathione reductase 3
mevalonate kinase 3
PAL 3
caspase-8 3
caspase-9 3
AMP-activated protein kinase 3
NADPH oxidase 3
furin 3
MMP-3 3
Lod 3
granzyme B 3
GAR 2
NQO1 2
CEP 2
prostate-specific membrane antigen 2
pepsin 2
DAT 2
succinic dehydrogenase 2
SOR 2
hyaluronidase 2
more...
Compound
Dec 3888
Clin 3860
His 626
water 561
oxygen 534
sodium 509
calcium 495
glucose 481
DNA 370
nitric oxide 350
5-HT 323
caffeine 310
creatinine 242
acetate 226
Cardiol 202
CO2 201
potassium 188
Estrogen 163
Sumatriptan 157
glutamate 132
DSM 121
ASA 117
noradrenaline 116
A 42 115
ethanol 112
iron 108
urea 104
ACTH 96
nitrate 94
prostacyclin 84
nitrogen 82
Isoproterenol 79
phosphate 79
salt 78
DTPA 77
arginine 71
Calcitonin 71
sulfate 71
TSH 70
Topiramate 70
aldosterone 65
TNF 63
GABA 63
GABA 60
retinoic acid 60
Nitroglycerin 59
Indomethacin 57
MCA 56
MCA 56
6-12 54
carbonate 54
APAP 54
mercury 52
iodine 51
formaldehyde 50
Zolmitriptan 49
tryptophan 49
glycerol 46
Nifedipine 46
methanol 46
A 71 46
Sildenafil 45
ADP 45
Propranolol 45
Valproic acid 44
formaldehyde 44
Verapamil 43
acetic acid 42
tryptophan 42
Propranolol 42
tryptophan 41
tryptophan 41
Pac 40
Histamine 39
ANCA 39
Ondansetron 39
ATP 39
tyrosine 38
Optimal 38
vitamin D 38
Verapamil 37
GMP 37
gamma-aminobutyric acid 37
cGMP 36
Methotrexate 36
Acetazolamide 36
copper 36
galactose 36
ADP 34
ADP 34
phosphorus 34
DBP 33
CAT 33
Estrogen 33
CAT 33
DBP 33
CAT 33
MAP 33
bromide 33
Lamotrigine 32
Amitriptyline 32
Ergotamine 31
ammonia 31
methionine 31
Lithium 31
lysine 30
leucine 30
Granisetron 30
PEG 29
TRH 29
NMDA 29
FK506 29
toluene 28
Dexamethasone 28
IMP 28
A 3 27
Prednisolone 26
Ibuprofen 26
homocysteine 26
HCl 26
Capsaicin 25
cAMP 25
Amphotericin B 25
titanium 24
S-adenosylhomocysteine 24
SAH 24
GPT 24
Thyroid 24
Cereb 24
Nimodipine 24
zinc 24
CTX 23
PGE2 23
Mg2+ 23
Doxycycline 23
T10 23
Cyclosporine 23
TBI 23
Warfarin 23
PAS 23
Praziquantel 22
Nicardipine 22
nickel 22
prostaglandin E1 22
Bromocriptine 22
DIC 22
Phe 22
CAM 21
coenzyme Q10 21
hydrogen 21
Amlodipine 21
Hemoglobin 21
Botulinum toxin type A 21
ACNU 21
silver 20
Naratriptan 20
PEG 20
aldehyde 20
glutamine 19
Neurotol 19
more...