Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of a 9-year-old girl scratched on the right side of her neck by a kitten about one month prior to admission. She was well until three weeks later when she developed enlarged right neck masses, a pustula on the scratch site, right injected conjunctiva, headache, general malaise and fever, thus fulfilling the clinical criteria for CSD. Initially, she was treated by a practicing physician but the manifestations persisted for one week. After admission, leukocytosis and a mildly elevated erythrocyte sedimentary rate were noted. The serum IgG titer to Bartonella henselae was performed by means of indirect fluorescent antibody (IFA) test at the National Institute of Preventive Medicine. The serum titer of anti-B, henselae Ig G was 1:256 and greater (> or = 1:256). The positive serum titer(negative titer being < 1:64) to B, henselae, the organism thought to be responsible for CSD, also supports this diagnosis. She was treated with a 7-day course of intravenous gentamicin and the fever subsided within 24 hours. Following this, she improved clinically and was discharged one week later. One month after discharge, she remained well with no palpable neck masses.
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PMID:Cat scratch disease in a child. 915 70

Acupuncture is known as the effective tool for headache, but the mechanism of the effect is unknown. We already revealed the acupuncture effect in the clinical team of headache center in Keio University Hospital. Therefore, we tried to establish the animal model for elucidation of mechanism of acupuncture effect in the pathophysiology of headache. Resent study, we reveal the threshold-reduction of the genesis of the cortical spreading depression (CSD; thought as the trigger of migraine attack) during the trigeminal nerve stimulation. This result suggests that, the somatosensory stimulation may influence the occurrence and severity of the pathogenesis of migraine. Furthermore, we assume that our result may lead to the underlying mechanism of acupuncture effect.
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PMID:[Acupuncture; as a valuable tool for headache]. 2319 97