Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In recent years a number of new preparations from the group of antiserotonin agents (including cyproheptadine and carbazochrome) as well as beta-adrenergic blocking agents (propranolol) and clonidine have been introduced for prevention of migraine and similar headaches. The efficiency of these drugs was studied in a group of 9 selected cases--adolescents with severe migraine refractory to other methods of treatment. In 7 cases the improvement was noted. The results were compared with own observations on larger groups of adults and data from literature. Too small number of observed patients made impossible definite conclusions. It seems, however that in selected cases the use of these drugs in headaches of adolescents is useful.
Neurol Neurochir Pol
PMID:[New anti-migraine drugs used in the treatment of children and adolescents]. 2 1

The pathogenesis of cluster headache remains unexplained and the immunological mechanisms have not been studied in this disease. Suspecting a possible allergic character of headache attacks it was decided to determine the haemolytic activity of the complement system and the levels of its C3 and C4 components. The investigations were carried out in 11 patients with cluster headache and in 10 patients with neurotic symptoms who served as controls. It was found that the levels of complement and its C4 fraction were not different in both groups but the level of C3 fraction showed a statistically significant difference. The authors discuss the obtained results and postulate continuation of investigations.
Neurol Neurochir Pol
PMID:[Levels of complement and its various fractions in the blood of patients with Horton's headache. Preliminary report]. 9 67

The authors present their observations on treatment with Noveril of nocturnal enuresis in 49 children aged from 6 to 16 years. The drug is a derivative of dibenzodiazepine belonging to the group of thymoleptic agents with an action similar to that of imipramine. Noveril was given in doses from 20 to 100 mg daily during 3 to 9 weeks. In the final evaluation of the drug the frequency of enuresis before, during and after treatment was taken into account. In 25 cases an improvement was observed, usually in psychogenic nocturnal enuresis. Side effects included oral dryness, headaches and dizziness, and sleep disturbances observed in 4 cases. The tolerance of the drug was good. Noveril has a favourable effect in children with nocturnal enuresis, particularly of psychogenic origin.
Neurol Neurochir Pol
PMID:[Treatment of enuresis with Noveril]. 24 45

The aim of this work was to study digestive tract function by means of xylose test in patients with attacks of headaches. The investigations were carried out in 14 patients with migraine, 10 with Horton's headache and 1 patient with both these conditions. In patients with migraine or Horton's headache the xylose test was normal in 65% of cases, in the remaining 35% (8 patients, 4 in each group) xylose elimination was abnormal, because it was below 30%. The authors discuss the factors which could influence the abnormal results of xylose test in these patients, since they had no signs of other diseases than the mentioned headaches.
Neurol Neurochir Pol
PMID:[Xylose test in patients with attacks of headaches (migraine, Horton's headache)]. 48 87

The authors report a 49-year-old man in whom continuous left-sided headaches increasing recently in intensity suggested presence of brain tumour. Sudden clinical deterioration on the 7th day of hospital observation was supposed to be due to brain-stem herniation. On autopsy a thrombus was found filling the basilar artery and the proximal parts of the posterior cerebral arteries with foci of softening in the right hemisphere, brain stem and left cerebellar hemisphere. The authors suppose that headaches were of vascular origin.
Neurol Neurochir Pol
PMID:[Basilar artery thrombosis with atypical course]. 59 9

The author analysed from the standpoint of familial history of headaches 89 cases of headaches treated at a neurological outpatient clinic in a period of 3 years. In 14 cases migraine was diagnosed, in 31 cases vasomotor headaches, in 16 post-traumatic headaches, in 7 psychogenic headaches, in 5 cases sinusitis, in 4 intracranial hypertension, in 12 cases the aetiology was unclear. In cases of vasomotor headaches in 90% of cases strong headaches were present in close relatives of the patients while in other groups the familial factor was infrequent.
Neurol Neurochir Pol
PMID:[Role of familial factor in vasomotor headache in children]. 60 Mar 46

In a 11-year-old girl with urinary tract infection symptoms and signs of Henoch-Schoenlein syndrome developed with neurological complications in the form of headaches, vomiting slightly marked signs of pyramidal tract and cerebellar damage and severe psychomotor temporal-lobe seizures. These very violent neurological manifestations disappeared completely after control of infection. The authors point out that prognosis in Henoch-Schoenlein syndrome even with such severe neurological complications is good.
Neurol Neurochir Pol
PMID:[Case of Henoch-Schoenlein purpura with neurological complications]. 67 27

In a group of 281 cases of subarachnoid haemorrhages including 105 cases of intracranial aneurysms confirmed on autopsy or by angiography the authors analyse the symptoms preceding subarachnoid haemorrhage and suggesting presence of aneurysm. The most frequent symptom suggesting presence of intracranial aneurysm were headaches, especially associated with other symptoms such as dizziness, nausea, paraesthesiae of extremities, visual disturbances. A careful analysis of these symptoms and early radiological examination may help in establishing the diagnosis of aneurysm before its rupture.
Neurol Neurochir Pol
PMID:[Symptoms preceding rupture of subarachnoid aneurysms: an analysis]. 68 25

The authors report the results of treatment with a modification of acupuncture associated with chemical stimulation in 144 patients with painful radicular syndromes and headaches. In 57 cases sciatic pains were present, in 21 cases shoulder pains, in 20 migraine and in 46 vasomotor headaches. Permanent disappearance of pain, that is disappearance of pain during the procedure and lack of recurrence within several successive days, was obtained in about 40% of cases of radicular syndromes and in 62% of cases of headaches, early disappearance of pain for 3 to 48 hours after the procedure was obtained in 14% of radicular syndromes and nearly 26% headaches, while improvement, that is reduction of pain intensity, was achieved in 29.5% of radicular pains and 3% of headaches, while in 15.3% of cases of radicular syndromes and 9% of cases of headaches no improvement was observed. Both vasomotor headaches and neuralgias belong to the group of nervous system diseases in which pain is the basic and sole symptom, while treatment includes its removal. In these cases acupuncture is a valuable analgesic method. The presently reported results agree with those in the literature on the use of classical acupuncture and its modifications. It is worth stressing that insertion of needles into the traditional points used in classical acupuncture is without any greater importance was shown by the presently reported experiences (various points were used in the same case) as well as by the reports of other authors. The modification of acupuncture with addition of chemical stimulation has been tried by the authors for 4 years. A weak stimulus resulting from insertion of the needle and irritation of the nerve endings with concentrated sodium chloride acts similarly as mechanical or electrical irritation. The method is simple and completely safe.
Neurol Neurochir Pol
PMID:[Modified acupuncture in the treatment of pain]. 68 27

In 50 patients with headaches and 50 with radicular pains pain sensitivity and pain tolerance as well as personality traits (Eysenck and Cattell questionnaire) were determined and a modification of acupuncture (with additional chemical stimulation) was used for treatment. The results of treatment were compared with personality traits. Differences were found in the personality traits between patients with paroxysmal headaches and patients with radicular pains. No statistically significant correlation was found, on the other hand, between the results of treatment and personality traits. The obtained results were best in the group of patients with paroxysmal headaches (permanent analgesic effect obtained in 70% of cases). The results of treatment obtained in the group of patients with continuous headaches and with radicular pains were similar. In patients with a lower threshold of pain sensitivity a higher proportion of permanent disappearance of pain was observed after treatment, and this observation may be useful for establishing indications to this therapy. Lack of any influence of personality traits on the result of this modified acupuncture may suggest that the basic analgesic action of these procedure is at lower levels of the nervous system and that it causes blockade of inflow of pain stimuli.
Neurol Neurochir Pol
PMID:[Type of pain, personality traits and effectiveness of modified acupuncture]. 68 28


1 2 3 4 5 6 7 8 9 10 Next >>