Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The article makes a comparative estimation of the efficiency between the benzodiazepine pharmacological group (selenium, diazepam) and adaptogens of the plant origin (Extractum Leuzeae carthamoidis fluidum) for correction of sleeping disorders in seamen during cruise. The application of elenium and diazepam have caused the unpleasant subjective sensations, such as psychoemotional retardation, sluggishness, apathism and headaches. After application of Extractum Leuzeae there were no side effects like a drug hang-over; the health status, functional state and job performance of seamen were improved. Having taken Extractum Leuzeae the seamen had the normalization of sleeping in 5-7 days.
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PMID:[A trial of the pharmacological correction of sleep disorders in sailors during a cruise]. 135 5

A massive expansion of mountain tourism and the practice of sports at altitude (mountaineering, skiing, cycling, hang-gliding, parapente, etc) has been observed in the last decades. This emphasis on new forms of sports and recreation represented as a social phenomenon is accompanied by an increase in the mountain associated-disorders and related-accidents. These include headache, lassitude, pain, difficulty in breathing, rapid heartbeat, and in the worst of the cases loss of consciousness, always possible, manifest by poor judgement, fatigue, etc, and death. However, medical studies are rare, mainly because the molecular mechanisms of tissue damage induced by oxygen free radicals are still poorly understood. Therefore, the goals of the present report are: 1) to summarize the main adaptations of the body at high altitude, introducing the concepts of altitude sickness and oxygen free radicals and their relation; 2) to propose a mechanism of action of oxygen free radicals in the development of this pathology, with special attention in hypoxia and related mechanisms; 3) to suggest a role for antioxidants in the therapy of altitude-related disorders.
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PMID:Role of oxygen free radicals in altitude-related disorders. 802 27