Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018681 (
headache
)
56,091
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We enrolled 118 chemonaive cancer patients (pts) to receive OND i.v. dl or
GRA
i.v. dl. Seventy of the 118 pts received moderately emetogenic (ME) chemotherapy (140 cycles), while 48 received highly emetogenic (HE) chemotherapy (93 cycles). Therapeutic success was obtained in 89% (OND) vs 94% (
GRA
) cycles of HE and in 96.8% (OND) vs 95.6% (
GRA
) cycles of ME. The main toxicities were
headache
(24%, OND; 23%,
GRA
); light-headedness (13%, OND; 18%,
GRA
); constipation (11%, OND; 6%,
GRA
). In conclusion, we think that OND and
GRA
are effective and the two drugs are equally active and toxic.
...
PMID:Ondansetron (OND) vs granisetron (GRA) in the control of chemotherapy induced acute emesis. 2159 82
