Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In an exploratory study of a general population of 209 young children (M = 12.9 yr. old), 59% of those with migraine or tension headache (n = 41) reported one or more triggers. More triggers were reported from those with tension headaches than from those with migrainous headaches.
Percept Mot Skills 1992 Aug
PMID:Perception of triggers in young nonclinical school students with migrainous headaches and with tension headaches. 152 82

This paper is concerned with the psychophysiology of "muscle-contraction" headaches in a group of Compensation patients suffering from multiple pain problems in addition to headaches. A total of 55 of these patients were divided into 4 groups which received frontalis EMG biofeedback, relaxation training, combined biofeedback-relaxation training, or no treatment. Differences were observed among the 3 experimental treatments and the control group with respect to headache changes, but there were no differences among groups with respect to the changes observed in four underlying physiological responses as a function of time or practice. While the subjects who showed the largest changes in headache characteristics were those who exhibited the largest decreases in frontalis EMG, these were also the subjects whose initial frontalis EMG levels were the highest. It is concluded that, in keeping with a growing literature, the link between frontalis EMG and "muscle-contraction" headaches is a tenuous one and that the changes brought about in headache symptomatology through biofeedback or relaxation training are most likely attributable to a generalization of feelings of mastery over the environment or of self-efficacy brought about in the subjects through apparent success at the task.
Percept Mot Skills 1986 Aug
PMID:Physiological changes after biofeedback and relaxation training for multiple-pain tension-headache patients. 294 69

In a study using metamizole and placebo as equivalents of a strong and a weak stimulus in a signal detection device female headaches patients show better ability to discriminate the two drug stimuli than males, whereas there is no significant effect with respect to response bias.
Percept Mot Skills 1985 Dec
PMID:Sex differences in perceiving analgesic drug effects as measured by subjective pain ratings: a concealed signal detection theory analysis. 408 66

224 (21%) of 1067 persons in a nonclinical population surveyed had one or more head injuries resulting in unconsciousness. They had a total of 306 head injuries with 113 (31%) of them resulting in lasting neurological effects. Both in a pilot project and in the main study, headache was the most commonly reported of an array of symptoms that are essentially a postconcussion syndrome.
Percept Mot Skills 1996 Dec
PMID:Incidence of head injury: lasting effects among college students and working adults in the general population. 901 50

31 subjects viewed an optokinetic rotating drum for 12 min. in one session and self-rotated by walking quickly around a vertical pole with eyes closed while alternately flexing and extending the neck in another session. The self-rotation session contained 6 trials (3 clockwise and 3 counterclockwise rotations). Each trial contained 20 cycles of self-rotations. Self-reported ratings of nausea and symptoms of motion sickness were obtained for each session. The subjects developed symptoms of nausea, sweating, dizziness, headache, drowsiness, and changes in salivation in both drum rotation and self-rotation sessions. However, the subjects reported higher ratings of nausea in the session of optokinetic rotation than in the session of self-rotation around a vertical pole. These results indicated that both optokinetic rotation and self-rotation with eyes closed while alternately flexing and extending the neck are effective means of inducing nausea and motion sickness.
Percept Mot Skills 2001 Aug
PMID:Susceptibility to motion sickness induced by optokinetic rotation and self-rotation by walking around a vertical pole. 1169 97

The possible relationships of migraine to left-handedness and left-eyedness, as well as sex and aura-related differences, were examined. 146 migraine patients (M age=32.1 yr., SD=9.5) and 141 controls (M age=30.0 yr., SD=9.3) participated. Hand preference was assessed by the modified version of the Edinburgh Handedness Inventory. Ocular dominance was measured by means of the near-far alignment test. Migraine diagnoses were made on the basis of criteria provided from the International Headache Society. In the overall sample and in women, left-handedness and left-eyedness were not significantly correlated with migraine. In men, the incidence of left-handedness and left-eyedness were significantly higher in patients than in controls. The presence of aura in patients with migraine was significantly associated with the incidence of left-eyedness and crossed hand-eye dominance, but not handedness, for the total sample and women. These results suggest that there may be a tendency towards anomalous dominance, especially left-eyedness, in migraine patients particularly those with aura.
Percept Mot Skills 2005 Jun
PMID:Handedness, eyedness, and crossed hand-eye dominance in male and female patients with migraine with and without aura: a pilot study. 1615

It was hypothesized that subjects with medical symptoms would show more signs of stress in projective drawings. A Stress Load Index, including five signs of stress in drawings, was evaluated. A questionnaire with an instruction to draw "a person in the rain" was sent to a cohort of 195 subjects, and the drawings were analysed blindly for eight stress items. Men had a higher index than women (p < .05) and drew clouds more often (p < .05). Drawing of clouds was associated with headache (adjOR = 4.28; 95% CI 1.75; 11.68). Drawing of puddles was associated with ocular symptoms (adjOR = 3.22; 95% CI 1.38, 7.50), facial dermal symptoms (adjOR= 2.94; 95% CI 1.28, 6.81), and tiredness (adjOR = 2.44; 95% CI 1.05, 5.67). Drawing of long rain strokes was associated with nasal symptoms (adjOR = 2.28; 95% CI 1.05, 2.06) and headache (adjOR = 3.20; 95% CI 1.28, 8.05). Age and stress load were predictors of sick building syndrome symptoms (p < .05). In conclusion, a nonverbal projective drawing test detected sex differences which represent directions opposite to those with verbal methods. These need empirical assessment.
Percept Mot Skills 2007 Feb
PMID:Projective drawings for assessing stress among subjects with medical symptoms compatible with sick building syndrome, and validation of a modified version of the Stress Load Index from the Drawing Personality Profile: a pilot study. 1745 Sep 71

773 children (359 girls, 414 boys) of two age groups, 10 years and 14 years, completed a questionnaire about subjective experiences of home and school. Children who reported getting along well with their parents and finding it easy to communicate with them also reported being more satisfied with themselves, enjoying school more, feeling less lonely, being less bullied by others, and also bullying others less. Boys reported bullying more than girls and more satisfaction with themselves than girls. Girls reported enjoying school more, feeling lonelier, sometimes having trouble falling asleep, and having headaches more often than boys. Girls at age 14 reported experiencing a prominent increase in headaches and parental complaints about their eating habits.
Percept Mot Skills 2007 Jun
PMID:Relationship between home and school adjustment: children's experiences at ages 10 and 14. 1768 53

Objective: To investigate the clinical features and imaging characteristics of mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS).Methods: Seventeen patients with MELAS diagnosed in the Affiliated Hospital of Xuzhou Medical University from July 2014 to August 2018 were enrolled in this study and their clinical manifestations, imaging and histopathological features were retrospectively analysed. We also discussed and summarised the related literature.Results: All of the 12 patients had seizures; stroke-like episodes in 12 cases; audio-visual impairment in 12 cases; headache in six cases; dysplasia in four cases; mental retardation in three cases; ataxia in two cases. On cranial magnetic resonance (MR) scans, the most common manifestations were in temporal-occipital-parietal lobe, cortical or subcortical areas as well as frontal lobe, thalamus, and basal ganglia showing long or equal T1 signals, long T2 signals, and hyperintense or iso-intense diffusion-weighted imaging (DWI) signals accompanied by ventricular enlargement and brain atrophy. MR spectroscopy showed that lactic acid peaks could be found in lesion sites, normal brain tissues, and cerebrospinal fluid. Muscle biopsy and genetic testing are the gold standard for diagnosing MELAS, muscle biopsy revealed COX-negative muscle fibres and SDH-stained red ragged fibres (RRF) under the sarcolemma. Mutations of mtDNA A3243G locus were common on gene testing. Improvement of mitochondrial function was observed after symptomatic and supportive treatment.Conclusion: MELAS should be considered for patients with epileptic seizures, headache, stroke-like episodes, extraocular palsy, cognitive decline and other clinical manifestations with the lesion located in the temporal-occipital-parietal lobe regardless of the distribution of blood vessels, and further examinations including muscle biopsy and gene testing should be performed to confirm the diagnosis.
Somatosens Mot Res 2020 03
PMID:An analysis of the clinical and imaging features of mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). 3200 May 57