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 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a rural area of western Kenya, primary schoolchildren's health seeking behaviour in response to common illnesses was investigated. 57 primary schoolchildren (age 11-17 years, median 13 years) were interviewed weekly about their health status and health seeking activities for 30 weeks. The children each experienced on average 25 illness episodes during this period. Most episodes could be categorised into 4 groups: 'cold', 'headache', 'abdominal complaints' and 'injuries'. One fifth (21%) of the illness episodes were serious enough to keep the children from school. In 28% of them, an adult was consulted, while 72% were not reported to an adult caretaker. Of the episodes without adult involvement, 81% remained untreated, while 19% were treated by the children themselves with either herbal or Western medicines. Of all the medicines taken by the children, two thirds were provided or facilitated by adults (assisted treatment) and one third taken by the children themselves without adult involvement (self-treatment). Among boys, the proportion of illnesses, which were self-treated increased with age from 12% in the youngest age group (< 13 years) to 34% in the oldest (> 14 years). In girls, the proportion of illnesses which were self-treated was consistently lower than among boys and remained constant around 9% for all age groups. The proportion of Western pharmaceuticals used for self-treatment increased with age from 44% in the youngest age group to 63% in the oldest (average 52% Western pharmaceuticals). Again, there were differences between boys and girls: among the youngest age group, boys were twice as likely to use pharmaceuticals than girls (62 versus 32% of the self-treatments, respectively) and in the oldest age group they were nearly three times more likely (75 versus 25%, respectively). These differences in self-treatment practices and choice of medicines between girls and boys may reflect the higher income potential of boys, who can earn money by fishing. Pharmaceuticals were generally preferred for the treatment of headache and fevers, or colds, while herbal remedies were the preferred choice for the treatment of abdominal complaints and wounds. The most commonly used pharmaceuticals were antimalarials (mainly chloroquine), painkillers and antipyretics (mainly aspirin and paracetamol), which were stocked in most small shops in the village at low prices and readily sold to children. Throughout primary school age Kenyan children are growing into a pluralistic medical practice, integrating Western pharmaceuticals into the local herbal medical system, and gradually become autonomous agents in their health care.
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PMID:Children and medicines: self-treatment of common illnesses among Luo schoolchildren in western Kenya. 1079 31

This article examines gendered work-health relationships among female factory workers in Rio Tinto, a textile factory town in Brazil. The author draws on her own and her parents' experiences as factory workers and as residents of Rio Tinto. In addition, she gathered research during 1982-86 and 1988-93, interviewing 30 female and 12 male workers. Findings from 1924-58 and 1959-91 indicate that the family structure and work process were interlinked. Self-images are construed to be the intersection of social relations of sex and class, psychopathology, and the concept of work positions. Gendered relations are a social construction, and awareness of these relations is based on a hierarchy and form of power based on a gendered division of labor. Gendered relations arise out of a specific historical context. Social practices reflect the relationship between sexual division of labor and gendered social relations, their modalities, shape, and periodization. The work-health relationship is expressed in the gendered technical organization of work, the gendered socialization of work, and domestic labor. The period of 1917-58 reflects the capitalist influences. When women became wage earners, their management of household tasks was changed. Men took over the heavy tasks, and women performed tasks that required skill and patience. Work-related health impacts, such as deformed knees or severed fingers, and accidents varied with the task. Women adapted to work conditions. During the 1940s, female workers refused to join the collective protests of men for better wages and conditions. The dream of progress faded by 1964. After 1959, new gendered relations of production and reproduction emerged. Labor laws were passed; new machines were introduced. During 1965-70, the health issues were headaches, irritability, and anxiety. 1970-91 brought a hollowness of spirit and the search for an explanation for the violence they had experienced.
Fem Psychol 1996
PMID:Gender relations, the gendered division of labour and health: the case of the women factory workers of Rio Tinto, northeast Brazil, 1924-91. 1229 20

Sitamaquine (WR6026) is an 8-aminoquinoline in development for the oral treatment of visceral leishmaniasis (VL). This was an open-label, dose-increasing study to determine the dose-response and safety profile for sitamaquine in Kenyan patients with VL caused by Leishmania donovani. Patients (mean age 15.9 [range = 5-47] years) received sitamaquine daily for 28 days at one of four doses: 1.75 (n = 12), 2.0 (n = 61), 2.5 (n = 12), or 3.0 (n = 12) mg/kg/day. The primary efficacy outcome was cure (absence of parasites on splenic aspirate) in the intent-to-treat population at day 180. Cure was achieved in 79 (83%) of 95 patients overall, and in 11 (92%) of 12, 49 (80%) of 61, 9 (82%) of 11, and 10 (91%) of 11 patients at sitamaquine doses of 1.75, 2.0, 2.5, or 3.0 mg/kg/day, respectively. The most frequent adverse events during active treatment were abdominal pain (12 [12%] of 97) and headache (11 [11%] of 97), and one patient in each of the 2.5 mg/kg/day and 3.0 mg/kg/day dose groups had a severe renal adverse event. The effects of sitamaquine on the kidney need further investigation. Sitamaquine was efficacious and generally well tolerated in Kenyan patients with VL.
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PMID:A phase II dose-increasing study of sitamaquine for the treatment of visceral leishmaniasis in Kenya. 1628 96

"Hierba santa," a Peruvian herbal medicine, is used to alleviate many symptoms, including headache, hemorrhoids, fever, and rheumatism. Several Cestrum species are said to be the origin of hierba santa. Three lots of hierba santa: Cestrum auriculatum (herb 1 and herb 2) and C. hediundinum (herb 3), which were purchased from Peruvian markets at Cuzco (Andes area) and Equitos (Amazon area), respectively, were examined for their pharmacological activities and active components. Herbs 1-3 showed anti-inflammatory and analgesic activities in the in vivo writhing inhibition test in mouse and inhibited prostaglandin E(1)-, E(2)-, or ACh-induced contractions of guinea pig ileum in the Magnus method. Activity-based separation of each extract yielded cestrumines A and B, cestrusides A and B, a mixture of (+)- and (-)-pinoresinol glucosides, nicotiflorin, rutin, sinapoyl glucose, ursolic acid, beta-sitosteryl glucoside, and 2-sec-butyl-4,6-dihydroxyphenyl-beta-D: -glucopyranoside. Among them, cestrumine A and cestrusides A and B are new compounds. All three lots of hierba santa do not contain exactly the same active components.
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PMID:Anti-inflammatory and analgesic components from "hierba santa," a traditional medicine in Peru. 1906 16